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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Jan. 01, 2019 | Jan. 01, 2018
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Increase in cash flows from financing activities as compared to previously reported amounts | $ 111,332,000 | $ 21,082,000 |  |
Cumulative adjustment to accumulated deficit |  | 207,000 |  |
Lease practical expedients | true |  |  |
Derivative liability |  | 0 |  |
Reduction to research and development expenses | $ 50,000 | 100,000 |  |
Software |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 3 years |  |  |
Computer equipment |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 3 years |  |  |
Furniture | Minimum |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 3 years |  |  |
Furniture | Maximum |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 7 years |  |  |
Leasehold improvements | Minimum |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 3 years |  |  |
Leasehold improvements | Maximum |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives | 7 years |  |  |
Subsequent Event |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Right of use assets |  |  | $ 2,500,000 |
Lease liabilities |  |  | $ 2,300,000 |
Accumulated Deficit |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Cumulative adjustment to accumulated deficit |  | $ 207,000 |  |
ISU Abxis |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Accounts receivable | $ 10,000 |  |  |
ASU 2016-18 |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Increase in cash flows from financing activities as compared to previously reported amounts | $ 5,300,000 |  |  |
ASU 2014-09 | ISU Abxis | Difference between Revenue Guidance in Effect before and after Topic 606 | Accumulated Deficit |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Cumulative adjustment to accumulated deficit |  |  |  | $ 200,000

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