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Reconciliation of Statutory Federal Income Tax (benefit) Rate to Company's Effective Tax Rate (Detail) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Income Tax Disclosure [Abstract] |  |
Tax at statutory federal rate | (21.00%) | (34.00%)
State Tax (benefit)—net of federal benefit | (0.03%) | (0.00%)
Permanent differences | 0.68% | 0.60%
R&D credits | (0.76%) | (1.64%)
Derecognition due to Sec. 382 and 383 limitations | (20.16%) | 54.08%
Change in valuation allowance | 39.33% | (52.90%)
Federal tax rate change | (0.00%) | 33.89%
Other | 1.94% | (0.03%)

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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 6.I) -URI http://asc.fasb.org/extlink&oid=34349781&loc=d3e330036-122817 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32698-109319 + Details
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