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Stockholders' Equity - Additional Information (Detail) - USD ($) |  |  |  |  |  | 12 Months Ended | 22 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Feb. 15, 2018 | Feb. 13, 2018 | Dec. 22, 2017 | Dec. 20, 2017 | Apr. 12, 2017 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2017 | Dec. 31, 2016 | Mar. 16, 2016
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, value of shares issued under sales agreement |  |  |  |  |  | $ 12,000 | $ 6,000 | $ 6,000 |  |
Net proceeds from sale of common stock | $ 106,800,000 |  | $ 9,700,000 |  | $ 18,600,000 |  | $ 5,336,000 |  |  |
Warrants to purchase common stock |  |  |  |  | 2,070,000 |  |  |  |  |
Warrants exercise price |  |  |  |  | $ 5.50 | $ 155.73 |  |  | $ 145.11 |
Preferred stock, shares issued |  |  |  |  |  | 0 | 3,680 | 3,680 |  |
Preferred stock, shares outstanding |  |  |  |  |  | 0 | 3,680 | 3,680 |  |
Net proceeds allocated to common stock, preferred A stock and warrants |  |  |  |  |  |  | $ 18,563,000 |  |  |
Common stock price, per share |  |  |  |  | $ 5.28 |  |  |  |  |
Proceeds allocated to warrants, net |  |  |  |  | $ 5,000,000 |  |  |  |  |
Number of warrants outstanding |  |  |  |  |  | 10,194 | 1,751,708 | 1,751,708 | 12,039 |
Overallotment Option |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Warrants to purchase common stock |  |  |  |  | 270,000 |  |  |  |  |
April 2017 Underwritten Public Offering |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Number of warrants outstanding |  |  |  |  |  | 0 |  |  |  |
Series A Preferred Stock |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Issuance of stock, shares |  |  |  |  | 13,350 |  |  |  |  |
Conversion of each preferred stock to common stock |  |  |  |  | 200 |  |  |  |  |
Number of shares converted |  |  |  |  |  | 3,680 | 9,670 |  |  |
Preferred stock, shares issued |  |  |  |  |  | 0 |  |  |  |
Preferred stock, shares outstanding |  |  |  |  |  | 0 | 3,680 | 3,680 |  |
Net proceeds allocated to preferred stock |  |  |  |  |  |  | $ 10,100,000 |  |  |
Effective conversion price |  |  |  |  |  |  | $ 3.80 | $ 3.80 |  |
Intrinsic value of preferred stock |  |  |  |  | $ 4,000,000 |  |  |  |  |
Effective percentage of conversion rights |  |  |  |  | 100.00% |  |  |  |  |
Common Stock |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Issuance of stock, shares | 3,382,352 |  | 1,105,263 |  | 1,470,000 |  | 439,880 |  |  |
Conversion of preferred stock to common stock |  |  |  |  |  | 736,000 | 1,934,000 |  |  |
Common stock price, per share | $ 34.00 |  | $ 9.50 |  |  |  |  |  |  |
Firm commitment underwritten public offering shares |  | 2,941,176 |  | 1,105,263 |  |  |  |  |  |
Common Stock | Overallotment Option |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Issuance of stock, shares | 441,176 |  |  |  | 540,000 |  |  |  |  |
Capital on Demand Sales Agreement with Jones Trading Institutional Services LLC |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Issuance of stock, shares |  |  |  |  |  |  |  | 479,681 |  |
Common stock weighted average selling price |  |  |  |  |  |  |  | $ 13.55 |  |
Net proceeds from sale of common stock |  |  |  |  |  |  | $ 5,500,000 | $ 6,300,000 |  |
Commission against additional paid-in capital |  |  |  |  |  |  |  | $ 200,000 |  |
Common stock available for sale |  |  |  |  |  |  | 0 | 0 |  |
Capital on Demand Sales Agreement with Jones Trading Institutional Services LLC | Maximum |  |  |  |  |  |  |  |  |  |
Stockholders Equity Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Common stock, value of shares issued under sales agreement |  |  |  |  |  |  |  |  |  | $ 6,500,000

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