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Consolidated Statements of Operations - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Statement [Abstract]    
Contract revenue $ 6 $ 1,018
Type of Revenue [Extensible List] cbio:ContractMember cbio:ContractMember
Operating expenses:    
Research and development $ 21,474 $ 12,847
General and administrative 12,354 9,993
Total operating expenses 33,828 22,840
Loss from operations (33,822) (21,822)
Interest and other income, net 3,767 261
Net loss (30,055) (21,561)
Deemed dividend for convertible preferred stock beneficial conversion feature   (3,951)
Net loss attributable to common stockholders $ (30,055) $ (25,512)
Net loss per share attributable to common stockholders, basic and diluted $ (2.68) $ (7.45)
Shares used to compute net loss per share attributable to common stockholders, basic and diluted 11,213,884 3,423,901