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Reconciliation of Statutory Federal Income Tax (benefit) Rate to Company's Effective Tax Rate (Detail)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]    
Tax at statutory federal rate (21.00%) (34.00%)
State Tax (benefit)—net of federal benefit (0.03%) (0.00%)
Permanent differences 0.68% 0.60%
R&D credits (0.76%) (1.64%)
Derecognition due to Sec. 382 and 383 limitations (20.16%) 54.08%
Change in valuation allowance 39.33% (52.90%)
Federal tax rate change (0.00%) 33.89%
Other 1.94% (0.03%)