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Condensed Consolidated Statement of Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Convertible Preferred Stock
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Balance at Dec. 31, 2017 $ 30,774   $ 6 $ 204,262   $ (173,494)
Balance (in shares) at Dec. 31, 2017   3,680 6,081,230      
Opening balance adjustment - adoption of ASC 606 at Dec. 31, 2017 207         207
Balance at Dec. 31, 2017 30,981   $ 6 204,262   (173,287)
Stock-based compensation expense 606     606    
Issuance of common stock for secondary public offering, net of issuance costs 106,762   $ 4 106,758    
Issuance of common stock for secondary public offering, net of issuance costs, shares     3,382,352      
Issuance of common stock upon exercise of warrants 9,545   $ 2 9,543    
Issuance of common stock upon exercise of warrants, shares     1,735,419      
Conversion of preferred stock to common stock, shares   (3,680) 736,000      
Issuance of common stock from stock grants and option exercises, shares     59      
Conversion of redeemable convertible notes to common stock, value 3     3    
Conversion of redeemable convertible notes to common stock, shares     21      
Unrealized gain (loss) on available-for-sale securities (4)       $ (4)  
Net loss (5,042)         (5,042)
Balance at Mar. 31, 2018 142,851   $ 12 321,172 (4) (178,329)
Balance (in shares) at Mar. 31, 2018     11,935,081      
Balance at Dec. 31, 2018 119,945   $ 12 323,279 (4) (203,342)
Balance (in shares) at Dec. 31, 2018     11,954,528      
Stock-based compensation expense 829     829    
Issuance of common stock from stock grants and option exercises 106     106    
Issuance of common stock from stock grants and option exercises, shares     19,576      
Unrealized gain (loss) on available-for-sale securities 17       17  
Net loss (15,083)         (15,083)
Balance at Mar. 31, 2019 $ 105,814   $ 12 $ 324,214 $ 13 $ (218,425)
Balance (in shares) at Mar. 31, 2019     11,974,104