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Summary of Stock-Based Compensation Recognized (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation $ 903 $ 551 $ 1,732 $ 1,156
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation 284 137 522 252
General and Administrative        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation [1] $ 619 $ 414 $ 1,210 $ 904
[1] Included $0.03 and $0.1 million in modifications related to certain Board member stock options in the three and six months ended June 30, 2019 and for the six months ended June 30, 2018, respectively.