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Related Parties - Additional Information (Detail) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Mosaic | Strategic Research Collaboration to Develop Intravitreal Anti-Complement Factor 3 Products        
Related Party Transaction [Line Items]        
Expenses related to collaboration $ 0.3 $ 0.3 $ 0.7 $ 0.5