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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Convertible Preferred Stock
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Balance at Dec. 31, 2017 $ 30,774   $ 6 $ 204,262   $ (173,494)
Balance (in shares) at Dec. 31, 2017   3,680 6,081,230      
Opening balance adjustment - adoption of ASC 606 at Dec. 31, 2017 207         207
Balance at Dec. 31, 2017 30,981   $ 6 204,262   (173,287)
Stock-based compensation expense 2,606   6,790 2,606    
Issuance of common stock for follow-on offering, net of issuance costs 106,762   $ 4 106,758    
Issuance of common stock for follow-on offering, net of issuance costs, shares     3,382,352      
Issuance of common stock upon exercise of warrants 9,545   $ 2 9,543    
Issuance of common stock upon exercise of warrants, shares     1,735,419      
Conversion of preferred stock to common stock, shares   (3,680) 736,000      
Issuance of common stock from stock grants and option exercises 107     107    
Issuance of common stock from stock grants and option exercises     12,716      
Conversion of redeemable convertible notes to common stock 3     3    
Conversion of redeemable convertible notes to common stock, shares     21      
Unrealized gain (loss) on available-for-sale debt securities (4)       $ (4)  
Net loss (30,055)         (30,055)
Balance at Dec. 31, 2018 119,945   $ 12 323,279 (4) (203,342)
Balance (in shares) at Dec. 31, 2018     11,954,528      
Stock-based compensation expense 3,204   $ 24,235 3,204    
Issuance of common stock from stock grants and option exercises 327     327    
Issuance of common stock from stock grants and option exercises     62,072      
Unrealized gain (loss) on available-for-sale debt securities 38       38  
Net loss (55,178)         (55,178)
Balance at Dec. 31, 2019 $ 68,336   $ 12 $ 326,810 $ 34 $ (258,520)
Balance (in shares) at Dec. 31, 2019     12,040,835