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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Operating Activities    
Net loss $ (56,241) $ (55,178)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 3,627 3,204
Depreciation and amortization 138 146
Changes in operating assets and liabilities:    
Accounts receivable 11,687 (15,000)
Prepaid and other assets (3,043) (490)
Accounts payable 1,652 3,031
Accrued compensation and other accrued liabilities 82 5,599
Operating lease liability and right-of-use asset 67 75
Deferred revenue (13,017) 15,000
Net cash flows used in operating activities (55,048) (43,613)
Investing Activities    
Proceeds from maturities of short-term investments 107,565 157,433
Purchase of short-term and long-term investments (97,635) (129,977)
Purchases of property and equipment (267) (64)
Net cash flows provided by investing activities 9,663 27,392
Financing Activities    
Issuance of common stock for public offering, net of issuance costs 59,941  
Issuance of common stock from ESPP purchase and stock option exercises 435 327
Net cash flows provided by financing activities 60,376 327
Net increase (decrease) in cash and cash equivalents 14,991 (15,894)
Cash and cash equivalents at beginning of the period 15,369 31,263
Cash and cash equivalents at end of the period 30,360 15,369
Supplemental Disclosure of Non-Cash Investing and Financing Activities:    
Right-of-use asset and operating lease liability recorded upon the adoption of ASC 842   $ 2,052
Right-of-use assets obtained in exchange for operating lease liabilities $ 476