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Related Parties - Additional Information (Detail) - USD ($)
$ in Millions
3 Months Ended
May 08, 2020
Mar. 31, 2021
Jan. 10, 2020
Mosaic      
Related Party Transaction [Line Items]      
Expenses related to collaboration $ 0.8    
Mosaic | Maximum      
Related Party Transaction [Line Items]      
Milestone payments , clinical development events   $ 4.0  
License and Collaboration Agreement (the “Biogen Agreement”)      
Related Party Transaction [Line Items]      
Upfront license fee received from collaboration agreement     $ 15.0