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Collaborations - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 31, 2020
Dec. 31, 2018
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue     $ 2,299,000 $ 893,000 $ 4,898,000 $ 18,917,000
Deferred revenue, recognized         1,600,000  
License            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue       32,000   15,100,000
License | Transfer of Exclusive License and Related Know-How            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue           15,000,000.0
Exclusive License            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue           100,000
Collaboration            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue     2,299,000 861,000 4,898,000 3,817,000
Collaboration | Reimbursable Out-of-Pocket and Personnel Costs Incurred Related to Research Services            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue     $ 2,300,000 $ 900,000 4,900,000 $ 3,800,000
ISU Abxis | Amended and Restated License Agreement            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
Regulatory and development milestone payment   $ 2,500,000     0  
ISU Abxis | Amended and Restated License Agreement | Maximum            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
Milestone payment   19,500,000     0  
Commercial milestone payments   $ 17,000,000.0     0  
Biogen            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
License and collaboration revenue         $ 0  
Biogen | License and Collaboration Agreement (the “Biogen Agreement”)            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
Research services         30 months  
Research services option to extend         12 months  
Biogen | Exclusive License            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
Up-front payments received $ 15,000,000.0          
Biogen | Exclusive License | Maximum            
Revenue Recognition Multiple Deliverable Arrangements [Line Items]            
Development and sales milestone payments $ 340,000,000.0