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Summary of Stock-Based Compensation Expense Recognized (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense $ 713 $ 1,068 $ 2,722 $ 2,707
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense 158 493 921 1,151
General and Administrative        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total stock-based compensation expense [1] $ 555 $ 575 $ 1,801 $ 1,556
[1]

Included in general and administrative for the three and nine months ended September 30, 2021 is stock-based compensation expense related to 15,961 shares and 39,823 shares, respectively, of common stock issued to certain board members in lieu of their cash compensation.