<SEC-DOCUMENT>0001193125-21-297901.txt : 20211013
<SEC-HEADER>0001193125-21-297901.hdr.sgml : 20211013
<ACCEPTANCE-DATETIME>20211013165256
ACCESSION NUMBER:		0001193125-21-297901
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		15
CONFORMED PERIOD OF REPORT:	20211007
ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20211013
DATE AS OF CHANGE:		20211013

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CATALYST BIOSCIENCES, INC.
		CENTRAL INDEX KEY:			0001124105
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				562020050
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51173
		FILM NUMBER:		211321733

	BUSINESS ADDRESS:	
		STREET 1:		611 GATEWAY BLVD., SUITE 710
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		650-871-0761

	MAIL ADDRESS:	
		STREET 1:		611 GATEWAY BLVD., SUITE 710
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGACEPT INC
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>d230267d8k.htm
<DESCRIPTION>8-K
<TEXT>
<XBRL>
<?xml version="1.0" encoding="utf-8" ?>
<html xmlns:dei="http://xbrl.sec.gov/dei/2020-01-31" xmlns:us-types="http://fasb.org/us-types/2020-01-31" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:cbio="http://www.catalystbiosciences.com/20211007" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:utr="http://www.xbrl.org/2009/utr" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:ix="http://www.xbrl.org/2013/inlineXBRL" xmlns:ixt="http://www.xbrl.org/inlineXBRL/transformation/2015-02-26" xmlns:ixt-sec="http://www.sec.gov/inlineXBRL/transformation/2015-08-31" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns="http://www.w3.org/1999/xhtml">
<head>
<title>8-K</title>
<meta http-equiv="Content-Type" content="text/html" />
</head>
   <body><div style="display:none"> <ix:header> <ix:hidden> <ix:nonNumeric name="dei:AmendmentFlag" contextRef="duration_2021-10-07_to_2021-10-07">false</ix:nonNumeric> <ix:nonNumeric id="Hidden_dei_EntityCentralIndexKey" name="dei:EntityCentralIndexKey" contextRef="duration_2021-10-07_to_2021-10-07">0001124105</ix:nonNumeric> </ix:hidden> <ix:references> <link:schemaRef xlink:type="simple" xlink:href="cbio-20211007.xsd" xlink:arcrole="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:link="http://www.xbrl.org/2003/linkbase"></link:schemaRef> </ix:references> <ix:resources> <xbrli:context id="duration_2021-10-07_to_2021-10-07"> <xbrli:entity> <xbrli:identifier scheme="http://www.sec.gov/CIK">0001124105</xbrli:identifier> </xbrli:entity> <xbrli:period> <xbrli:startDate>2021-10-07</xbrli:startDate> <xbrli:endDate>2021-10-07</xbrli:endDate> </xbrli:period> </xbrli:context> </ix:resources> </ix:header> </div> <div style="text-align:center"> <div style="width:8.5in;text-align:left;margin-left: auto;margin-right: auto"> <p style="line-height:1.0pt;margin-top:0pt;margin-bottom:0pt;border-bottom:1px solid #000000">&#160;</p> <p style="line-height:3.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1px solid #000000">&#160;</p> <p style="margin-top:4pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman;font-weight:bold;text-align:center">UNITED STATES</p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman;font-weight:bold;text-align:center">SECURITIES AND EXCHANGE COMMISSION</p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman;font-weight:bold;text-align:center">Washington, D.C. 20549</p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <div style="text-align:center"> <p style="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%;text-align:center;margin-left: auto;margin-right: auto">&#160;</p></div> <p style="margin-top:10pt; margin-bottom:0pt; font-size:18pt; font-family:Times New Roman;font-weight:bold;text-align:center">FORM <ix:nonNumeric name="dei:DocumentType" contextRef="duration_2021-10-07_to_2021-10-07">8-K</ix:nonNumeric></p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <div style="text-align:center"> <p style="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%;text-align:center;margin-left: auto;margin-right: auto">&#160;</p></div> <p style="margin-top:10pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman;font-weight:bold;text-align:center">CURRENT REPORT</p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman;font-weight:bold;text-align:center">Pursuant to Section 13 or 15(d)</p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman;font-weight:bold;text-align:center">of the Securities Exchange Act of 1934</p> <p style="margin-top:10pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman;font-weight:bold;text-align:center">Date of Report (Date of earliest event reported): <ix:nonNumeric name="dei:DocumentPeriodEndDate" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt:datemonthdayyearen">October 7, 2021</ix:nonNumeric></p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <div style="text-align:center"> <p style="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%;text-align:center;margin-left: auto;margin-right: auto">&#160;</p></div> <p style="margin-top:10pt; margin-bottom:0pt; font-size:24pt; font-family:Times New Roman;font-weight:bold;text-align:center"><ix:nonNumeric name="dei:EntityRegistrantName" contextRef="duration_2021-10-07_to_2021-10-07">CATALYST BIOSCIENCES, INC.</ix:nonNumeric></p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:center">(Exact name of registrant as specified in its charter)</p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <div style="text-align:center"> <p style="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%;text-align:center;margin-left: auto;margin-right: auto">&#160;</p></div> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table cellspacing="0" cellpadding="0" style="border-collapse:collapse; font-family:Times New Roman; font-size:10pt;width:100%;border:0;margin:0 auto">
<tr>
<td style="width:34%"></td>
<td style="vertical-align:bottom"></td>
<td style="width:32%"></td>
<td style="vertical-align:bottom;width:1%"></td>
<td style="width:32%"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:EntityIncorporationStateCountryCode" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:stateprovnameen">Delaware</ix:nonNumeric></span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:EntityFileNumber" contextRef="duration_2021-10-07_to_2021-10-07">000-51173</ix:nonNumeric></span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:EntityTaxIdentificationNumber" contextRef="duration_2021-10-07_to_2021-10-07">56-2020050</ix:nonNumeric></span></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:8pt">
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold">(State or other jurisdiction<br />of incorporation)</span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold">(Commission<br />File Number)</span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold">(IRS Employer<br />Identification No.)</span></td></tr></table> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:center"><ix:nonNumeric name="dei:EntityAddressAddressLine1" contextRef="duration_2021-10-07_to_2021-10-07">611 Gateway Blvd</ix:nonNumeric>, <ix:nonNumeric name="dei:EntityAddressAddressLine2" contextRef="duration_2021-10-07_to_2021-10-07">Suite 710</ix:nonNumeric>, <ix:nonNumeric name="dei:EntityAddressCityOrTown" contextRef="duration_2021-10-07_to_2021-10-07">South San Francisco</ix:nonNumeric>, <ix:nonNumeric name="dei:EntityAddressStateOrProvince" contextRef="duration_2021-10-07_to_2021-10-07">CA</ix:nonNumeric> <ix:nonNumeric name="dei:EntityAddressPostalZipCode" contextRef="duration_2021-10-07_to_2021-10-07">94080</ix:nonNumeric></p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">(Address of principal executive offices)</p> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:center"><ix:nonNumeric name="dei:CityAreaCode" contextRef="duration_2021-10-07_to_2021-10-07">(650)</ix:nonNumeric> <ix:nonNumeric name="dei:LocalPhoneNumber" contextRef="duration_2021-10-07_to_2021-10-07">871-0761</ix:nonNumeric></p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">(Registrant&#8217;s telephone number, including area code)</p> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:center">Not Applicable</p> <p style="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;text-align:center">(<span style="font-weight:bold">Former name or former address, if changed since last report.)</span></p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <div style="text-align:center"> <p style="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%;text-align:center;margin-left: auto;margin-right: auto">&#160;</p></div> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Check the appropriate box below if the Form <span style="white-space:nowrap">8-K</span> filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:</p> <p style="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table style="border-collapse:collapse; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:4%">&#160;</td>
<td style="width:5%;vertical-align:top"><ix:nonNumeric name="dei:WrittenCommunications" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></td>
<td style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;text-align:left">Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)</p></td></tr></table> <p style="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table style="border-collapse:collapse; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:4%">&#160;</td>
<td style="width:5%;vertical-align:top"><ix:nonNumeric name="dei:SolicitingMaterial" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></td>
<td style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;text-align:left">Soliciting material pursuant to Rule <span style="white-space:nowrap">14a-12</span> under the Exchange Act (17 CFR <span style="white-space:nowrap">240.14a-12)</span></p></td></tr></table> <p style="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table style="border-collapse:collapse; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:4%">&#160;</td>
<td style="width:5%;vertical-align:top"><ix:nonNumeric name="dei:PreCommencementTenderOffer" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></td>
<td style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;text-align:left"><span style="white-space:nowrap">Pre-commencement</span> communications pursuant to Rule <span style="white-space:nowrap">14d-2(b)</span> under the Exchange Act (17 CFR <span style="white-space:nowrap">240.14d-2(b))</span></p></td></tr></table> <p style="font-size:6pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table style="border-collapse:collapse; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:4%">&#160;</td>
<td style="width:5%;vertical-align:top"><ix:nonNumeric name="dei:PreCommencementIssuerTenderOffer" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></td>
<td style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;text-align:left"><span style="white-space:nowrap">Pre-commencement</span> communications pursuant to Rule <span style="white-space:nowrap">13e-4(c)</span> under the Exchange Act (17 CFR <span style="white-space:nowrap">240.13e-4(c))</span></p></td></tr></table> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Securities registered pursuant to Section&#160;12(b) of the Act:</p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table cellspacing="0" cellpadding="0" style="border-collapse:collapse; font-family:Times New Roman; font-size:8pt;width:100%;border:0;margin:0 auto">
<tr>
<td style="width:34%"></td>
<td style="vertical-align:bottom"></td>
<td style="width:32%"></td>
<td style="vertical-align:bottom;width:1%"></td>
<td style="width:32%"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:8pt">
<td style=" text-align: center;margin:auto; border-bottom:1.00pt solid #000000;vertical-align:bottom;white-space:nowrap"> <p style="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">Title of each class</p></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; border-bottom:1.00pt solid #000000;vertical-align:bottom"> <p style="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">Trading<br />Symbol(s)</p></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; border-bottom:1.00pt solid #000000;vertical-align:bottom"> <p style="margin-top:0pt; margin-bottom:1pt; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">Name of each exchange<br />on which registered</p></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:Security12bTitle" contextRef="duration_2021-10-07_to_2021-10-07">Common Stock</ix:nonNumeric></span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:TradingSymbol" contextRef="duration_2021-10-07_to_2021-10-07">CBIO</ix:nonNumeric></span></td>
<td style="vertical-align:bottom">&#160;</td>
<td style=" text-align: center;margin:auto; vertical-align:top"><span style="font-weight:bold"><ix:nonNumeric name="dei:SecurityExchangeName" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:exchnameen">Nasdaq</ix:nonNumeric></span></td></tr></table> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (&#167;&#160;230.405 of this chapter) or Rule <span style="white-space:nowrap">12b-2</span> of the Securities Exchange Act of 1934 (&#167; <span style="white-space:nowrap">240.12b-2</span> of this chapter).</p> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Emerging growth company <ix:nonNumeric name="dei:EntityEmergingGrowthCompany" contextRef="duration_2021-10-07_to_2021-10-07" format="ixt-sec:boolballotbox">&#9744;</ix:nonNumeric></p> <p style="margin-top:10pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section&#160;13(a) of the Exchange Act. &#9744;</p> <p style="font-size:10pt;margin-top:0pt;margin-bottom:0pt">&#160;</p> <p style="line-height:1.0pt;margin-top:0pt;margin-bottom:0pt;border-bottom:1px solid #000000">&#160;</p> <p style="line-height:3.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1px solid #000000">&#160;</p></div></div>

<p style="margin-top:1em; margin-bottom:0em; page-break-before:always"> </p>
<hr style="color:#999999;height:3px;width:100%" />

<div style="text-align:center"><div style="width:8.5in;text-align:left;margin-left: auto;margin-right: auto">

<table style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:11%;vertical-align:top" align="left"><span style="font-weight:bold">Item&#160;5.02</span></td>
<td align="left" style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:left">Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. </p></td></tr></table> <p style="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">On October&#160;7, 2021, Clinton Musil, Chief Financial Officer of Catalyst Biosciences, Inc. (the &#8220;Company&#8221;), notified the Company of his decision to resign for personal reasons. Mr.&#160;Musil&#8217;s resignation will be effective October&#160;29, 2021 (the &#8220;Effective Date&#8221;). The Company will initiate a search to identify a new Chief Financial Officer, and Mr.&#160;Musil will provide consulting services to the Company following the Effective Date. </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">On October&#160;13, 2021, the Company and Mr.&#160;Musil entered into a consulting agreement (the &#8220;Consulting Agreement&#8221;) pursuant to which Mr.&#160;Musil agreed to serve as a consultant to the Company following the Effective Date. </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Seline Miller, the Company&#8217;s Controller, was promoted to Senior Vice President, Finance and will serve as the Company&#8217;s interim Chief Financial Officer and interim Principal Accounting Officer. Mrs.&#160;Miller, age 52, joined the Company in March 2021 as Controller. Mrs.&#160;Miller served as the Chief Accounting Officer of Rezolute, Inc. from March 2019 until August 2019. From September 2019 to March 2021, Mrs.&#160;Miller provided consulting services to various biotechnology companies including Rezolute, Inc. From 2017 to 2019, Mrs.&#160;Miller was Vice President of Accounting and Corporate Controller at Textainer Group Holding. Prior to that, from 2015 to 2017, Mrs.&#160;Miller was Corporate Controller at Athoc, which was acquired by Blackberry. In 1990, Mrs.&#160;Miller started her career as a financial auditor within Price Waterhouse, now PricewaterhouseCoopers (PwC). Mrs.&#160;Miller, a member of the American Institute of Certified Public Accountants, obtained her Certified Public Accounting license in 1993 and earned her B.S. in Accounting from the University of Southern California. </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">In connection with Mrs.&#160;Miller&#8217;s promotion to Senior Vice President, Finance, and appointment as interim Chief Financial Officer and interim Principal Accounting Officer, Mrs.&#160;Miller will receive an increase in annual base compensation from $250,000 to $300,000 and a bonus target of 30% increased from 25%. </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">There are no family relationships between Mrs.&#160;Miller and any director or executive officer of the Company, and Mrs.&#160;Miller is not a party to any transaction required to be disclosed pursuant to Item 404(a) of Regulation <span style="white-space:nowrap">S-K.</span> There are no arrangements or understandings between Mrs.&#160;Miller and any other persons pursuant to which Mrs.&#160;Miller was appointed as the Company&#8217;s interim Principal Accounting Officer. </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">The above description of the Consulting Agreement is qualified in its entirety by reference to the full text of the Consulting Agreement, a copy of which is filed as Exhibit 10.1 to this Current Report on Form <span style="white-space:nowrap">8-K.</span> A copy of the press release issued by the Company is attached hereto as Exhibit 99.1 and incorporated by reference. </p> <p style="font-size:18pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt;border:0;width:100%" cellpadding="0" cellspacing="0">
<tr style="page-break-inside:avoid">
<td style="width:11%;vertical-align:top" align="left"><span style="font-weight:bold">Item&#160;9.01</span></td>
<td align="left" style="vertical-align:top"> <p style=" margin-top:0pt ; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:left">Financial Statements and Exhibits. </p></td></tr></table> <p style="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">(d)&#160;Exhibits </p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table cellspacing="0" cellpadding="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt;width:100%;border:0;margin:0 auto">


<tr>

<td></td>

<td style="vertical-align:bottom;width:4%"></td>
<td style="width:93%"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:8pt">
<td style="vertical-align:bottom;white-space:nowrap" align="center"> <p style=" margin-top:0pt ; margin-bottom:0pt; border-bottom:1.00pt solid #000000; display:inline-block; font-size:8pt; font-family:Times New Roman;font-weight:bold;text-align:center">Exhibit<br />No.</p></td>
<td style="vertical-align:bottom">&#160;&#160;</td>
<td style="vertical-align:bottom;white-space:nowrap"> <p style=" margin-top:0pt ; margin-bottom:0pt; border-bottom:1.00pt solid #000000; display:table-cell; font-size:8pt; font-family:Times New Roman;font-weight:bold">Description</p></td></tr>


<tr style="font-size:1pt">
<td style="height:6pt"></td>
<td style="height:6pt" colspan="2"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top;white-space:nowrap">10.1</td>
<td style="vertical-align:bottom">&#160;&#160;</td>
<td style="vertical-align:top"><a href="d230267dex101.htm">Consulting Agreement between Catalyst Biosciences, Inc. and Clinton Musil dated October&#160;13, 2021. </a></td></tr>
<tr style="font-size:1pt">
<td style="height:6pt"></td>
<td style="height:6pt" colspan="2"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top;white-space:nowrap">99.1</td>
<td style="vertical-align:bottom">&#160;&#160;</td>
<td style="vertical-align:top"><a href="d230267dex991.htm">Press release issued by Catalyst Biosciences, Inc. dated October&#160;13, 2021. </a></td></tr>
<tr style="font-size:1pt">
<td style="height:6pt"></td>
<td style="height:6pt" colspan="2"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top;white-space:nowrap">104</td>
<td style="vertical-align:bottom">&#160;&#160;</td>
<td style="vertical-align:top">Cover Page Interactive Data File (formatted as Inline XBRL).</td></tr>
</table>
</div></div>



<p style="margin-top:1em; margin-bottom:0em; page-break-before:always"> </p>
<hr style="color:#999999;height:3px;width:100%" />

<div style="text-align:center"><div style="width:8.5in;text-align:left;margin-left: auto;margin-right: auto">
 <p style="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman;font-weight:bold;text-align:center">SIGNATURES </p> <p style="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. </p> <p style="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&#160;</p>
<table cellspacing="0" cellpadding="0" style="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt;width:100%;border:0">


<tr>

<td style="width:47%"></td>

<td style="vertical-align:bottom;width:1%"></td>
<td style="width:4%"></td>

<td style="vertical-align:bottom"></td>
<td></td>

<td style="vertical-align:bottom;width:1%"></td>
<td style="width:46%"></td></tr>


<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom;white-space:nowrap"><span style="font-weight:bold">CATALYST BIOSCIENCES, INC.</span></td></tr>
<tr style="font-size:1pt">
<td style="height:12pt"></td>
<td style="height:12pt" colspan="2"></td>
<td style="height:12pt" colspan="2"></td>
<td style="height:12pt" colspan="2"></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top">Date: October&#160;13, 2021</td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom;white-space:nowrap"> <p style="margin-top:0pt; margin-bottom:1pt; border-bottom:1px solid #000000; font-size:10pt; font-family:Times New Roman">/s/ Nassim Usman, Ph.D.</p></td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom;white-space:nowrap">Nassim Usman, Ph.D.</td></tr>
<tr style="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<td style="vertical-align:top"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom"></td>
<td style="vertical-align:bottom">&#160;</td>
<td style="vertical-align:bottom;white-space:nowrap">President and Chief Executive Officer</td></tr>
</table>
</div></div>

</body></html>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>d230267dex101.htm
<DESCRIPTION>EX-10.1
<TEXT>
<HTML><HEAD>
<TITLE>EX-10.1</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="right"><B>Exhibit 10.1 </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>CATALYST BIOSCIENCES, INC. </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>CONSULTING AGREEMENT </B></P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">This
Consulting Agreement (this &#147;<U>Agreement</U>&#148;) is entered into as of 13&nbsp;October 2021 to be effective upon the date of termination of your employment (the &#147;<U>Effective Date</U>&#148;) between Catalyst Biosciences, Inc., a
Delaware corporation (&#147;<U>Company</U>&#148;), and Clinton Musil (&#147;<U>Consultant</U>&#148;). Company desires to retain Consultant to perform certain consulting activities as described below, and Consultant desires to serve as a consultant
to Company and perform such activities under the terms of this Agreement. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">NOW, THEREFORE, Consultant and Company agree as follows: </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>1.&nbsp;&nbsp;&nbsp;&nbsp;<U>SERVICES AND COMPENSATION</U> </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(a)&nbsp;&nbsp;&nbsp;&nbsp;Consultant agrees to act as a consultant to Company with respect to such matters and projects as are mutually
agreed from time to time by and between Consultant and Company, and to perform the services described on <U>Exhibit A</U> hereto (collectively, the &#147;<U>Services</U>&#148;). </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(b)&nbsp;&nbsp;&nbsp;&nbsp;Company agrees to pay Consultant the compensation set forth in <U>Exhibit</U><U></U><U>&nbsp;A</U> hereto for the
performance of the Services. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>2.&nbsp;&nbsp;&nbsp;&nbsp;<U>CONFIDENTIALITY</U> </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(a)&nbsp;&nbsp;&nbsp;&nbsp;&#147;<U>Confidential Information</U>&#148; means any proprietary information, technical data, trade secrets or <FONT
STYLE="white-space:nowrap">know-how,</FONT> including, but not limited to, research and product plans, products, services, markets, developments, inventions, processes, formulas, technology, marketing, finances or other business information
disclosed to Consultant by Company either directly or indirectly in writing, orally or otherwise. Confidential Information also includes all Inventions (as defined below) and any other information or materials generated in connection with the
Services. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(b)&nbsp;&nbsp;&nbsp;&nbsp;Consultant shall not, during or subsequent to the term of this Agreement, use any Confidential
Information for any purpose whatsoever other than the performance of the Services on behalf of Company, or disclose Confidential Information to any third party. Consultant agrees that Confidential Information shall remain the sole property of
Company. Consultant further agrees to take all reasonable precautions to prevent any unauthorized disclosure or use of Confidential Information. Notwithstanding the above, Consultant&#146;s obligation under this Section&nbsp;2(b) relating to
Confidential Information shall not apply to information which (i)&nbsp;is known to Consultant at the time of disclosure to Consultant by Company as evidenced by written records of Consultant, (ii)&nbsp;has become publicly known and made generally
available through no wrongful act of Consultant, or (iii)&nbsp;has been rightfully received by Consultant from a third party authorized to make such disclosure. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(c)&nbsp;&nbsp;&nbsp;&nbsp;Consultant agrees that Consultant will not, during the term of this Agreement, improperly use or disclose to
Company any proprietary information or trade secrets of any former or current employer or other person or entity to which Consultant has a duty to keep in confidence such information and that Consultant will not bring onto the premises of Company
any unpublished document or proprietary information belonging to such employer, person or entity unless consented to in writing by the same. Consultant will indemnify Company and hold it harmless from and against all claims, liabilities, damages and
expenses, including reasonable attorneys&#146; fees and costs of suit, arising out of or in connection with any violation or claimed violation by Company of such third party&#146;s rights resulting in whole or in part from Company&#146;s use of the
work product of Consultant under this Agreement. </P>
</DIV></Center>


<p style="margin-top:1em; margin-bottom:0em; page-break-before:always">
<HR SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(d)&nbsp;&nbsp;&nbsp;&nbsp;Consultant recognizes that Company has received and in the future
will receive from third parties their confidential or proprietary information subject to a duty on Company&#146;s part to maintain the confidentiality of such information and to use it only for certain limited purposes. Consultant agrees that
Consultant owes Company and such third parties, during the term of this Agreement and thereafter, a duty to hold all such confidential or proprietary information in the strictest confidence and not to disclose it to any person, firm or corporation
or to use it except as necessary in carrying out the Services for Company consistent with Company&#146;s agreement with such third party. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(e)&nbsp;&nbsp;&nbsp;&nbsp;Upon the termination of this Agreement, or upon Company&#146;s earlier request, Consultant will deliver to Company
all Confidential Information and Company&#146;s property relating thereto and all tangible embodiments thereof, in Consultant&#146;s possession or control. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(f)&nbsp;&nbsp;&nbsp;&nbsp;DTSA Notice. Consultant acknowledges receipt of the following notice pursuant to 18 U.S.C. &#167; 1833(b)(1)
(Defend Trade Secrets Act): </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">An individual shall not be held criminally or civilly liable under any federal or state trade secret law for
the disclosure of a trade secret that is made in confidence to a federal, state, or local government official or to an attorney solely for the purpose of reporting or investigating a suspected violation of law. An individual shall not be held
criminally or civilly liable under any federal or state trade secret law for the disclosure of a trade secret that is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal. An individual who
files a lawsuit for retaliation by an employer for reporting a suspected violation of law may disclose the trade secret to the attorney of the individual and use the trade secret information in the court proceeding, if the individual files any
document containing the trade secret under seal; and does not disclose the trade secret, except pursuant to court order. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>3.&nbsp;&nbsp;&nbsp;&nbsp;<U>OWNERSHIP</U> </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(a)&nbsp;&nbsp;&nbsp;&nbsp;Consultant hereby irrevocably assigns to Company all right, title and interest in and to any information
(including, without limitation, business plans and/or business information), technology, <FONT STYLE="white-space:nowrap">know-how,</FONT> materials, notes, records, designs, ideas, inventions, improvements, devices, developments, discoveries,
compositions, trade secrets, processes, methods and/or techniques, whether or not patentable or copyrightable, that are conceived, reduced to practice or made by Consultant alone or jointly with others in the course of performing the Services or
through the use of Confidential Information (collectively, &#147;<U>Inventions</U>&#148;). </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(b)&nbsp;&nbsp;&nbsp;&nbsp;Consultant agrees
to sign, execute and acknowledge or cause to be signed, executed and acknowledged without cost, but at the expense of Company, any and all documents and to perform such acts as may be necessary, useful or convenient for the purposes of perfecting
the foregoing assignments and obtaining, enforcing and defending intellectual property rights in any and all countries with respect to Inventions. It is understood and agreed that Company or Company&#146;s designee shall have the sole right, but not
the obligation, to prepare, file, prosecute and maintain patent applications and patents worldwide with respect to Inventions. </P>
 <p STYLE="margin-top:0pt;margin-bottom:0pt ; font-size:8pt">&nbsp;</P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">-2- </P>

</DIV></Center>


<p style="margin-top:1em; margin-bottom:0em; page-break-before:always">
<HR SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(c)&nbsp;&nbsp;&nbsp;&nbsp;Upon the termination of this Agreement, or upon Company&#146;s
earlier requests, Consultant will deliver to Company all property relating to, and all tangible embodiments of, Inventions in Consultant&#146;s possession or control. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(d)&nbsp;&nbsp;&nbsp;&nbsp;Consultant agrees that if, in the course of performing the Services, Consultant incorporates into any Invention
developed hereunder any invention, improvement, development concept, discovery or other proprietary subject matter owned by Consultant or in which Consultant has an interest (&#147;<U>Item</U>&#148;), Consultant will inform Company in writing
thereof, and Company is hereby granted and shall have a <FONT STYLE="white-space:nowrap">non-exclusive,</FONT> royalty-free, perpetual, irrevocable, worldwide license to make, have made, modify, reproduce, display, use and sell such Item as part of
or in connection with the exploitation of such Invention. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(e)&nbsp;&nbsp;&nbsp;&nbsp;Consultant agrees that if Company is unable because
of Consultant&#146;s unavailability, mental or physical incapacity, or for any other reason, to secure Consultant&#146;s signature to apply for or to pursue any application or registration for any intellectual property rights covering any Invention,
then Consultant hereby irrevocably designates and appoints Company and its duly authorized officers and agents as Consultant&#146;s agent and <FONT STYLE="white-space:nowrap"><FONT STYLE="white-space:nowrap">attorney-in-fact,</FONT></FONT> to act
for and in Consultant&#146;s behalf to execute and file any such applications and to do all other lawfully permitted acts to further the prosecution and issuance of such intellectual property rights thereon with the same legal force and effect as if
executed by Consultant. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>4.</B>&nbsp;&nbsp;&nbsp;&nbsp;<B><U>REPORTS</U></B>. Consultant agrees, from time to time during the term of this Agreement,
to keep Company advised as to Consultant&#146;s progress in performing the Services and, as reasonably requested by Company, prepare written reports with respect thereto. It is understood that the time required in the preparation of such written
reports shall be considered time devoted to the performance of the Services by Consultant. All such reports prepared by Consultant shall be the sole property of Company. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>5.&nbsp;&nbsp;&nbsp;&nbsp;<U>TERM AND TERMINATION</U> </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(a)&nbsp;&nbsp;&nbsp;&nbsp;This Agreement will commence on the Effective Date and will continue until the earlier of 31&nbsp;December 2021, or
termination as provided below. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(b)&nbsp;&nbsp;&nbsp;&nbsp;Either party may terminate this Agreement upon prior written notice thereof to
the other party. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(c)&nbsp;&nbsp;&nbsp;&nbsp;Either party may terminate this Agreement upon material breach by the other party provided
that the <FONT STYLE="white-space:nowrap">non-breaching</FONT> party shall provide written notice of such breach and an opportunity to cure such breach (if curable) for a period of thirty (30)&nbsp;days. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">(d)&nbsp;&nbsp;&nbsp;&nbsp;Upon termination of this Agreement, all rights and duties of the parties hereunder shall cease except: </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:9%; font-size:10pt; font-family:Times New Roman">(i)&nbsp;&nbsp;&nbsp;&nbsp;Company shall be obliged to pay, within thirty (30)&nbsp;days after receipt of Consultant&#146;s final statement,
all amounts owing to Consultant for unpaid Services completed by Consultant and related expenses, if any, in accordance with the provisions of Section&nbsp;1 hereof, and </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; text-indent:9%; font-size:10pt; font-family:Times New Roman">(ii)&nbsp;&nbsp;&nbsp;&nbsp;Sections&nbsp;2, 3, 5(d), 6, 7 and 9 shall survive termination of this Agreement. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>6.</B>&nbsp;&nbsp;&nbsp;&nbsp;<B><U>INDEPENDENT CONTRACTOR</U></B>. Nothing in this Agreement shall in any way be construed to constitute Consultant as an
agent, employee or representative of Company, but Consultant shall perform the Services as an independent contractor. Consultant acknowledges and agrees that Consultant is obligated to report as income all compensation received by Consultant
pursuant to this Agreement. </P>
 <p STYLE="margin-top:0pt;margin-bottom:0pt ; font-size:8pt">&nbsp;</P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">-3- </P>

</DIV></Center>


<p style="margin-top:1em; margin-bottom:0em; page-break-before:always">
<HR SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>7.</B>&nbsp;&nbsp;&nbsp;&nbsp;<B><U>ARBITRATION AND EQUITABLE RELIEF</U></B>. Company and Consultant
agree that any dispute or controversy arising out of, in relation to, or in connection with this Agreement, or the making, interpretation, construction, performance or breach hereof, shall be finally settled by binding arbitration in San Francisco,
California under the then current rules of the American Arbitration Association by one (1)&nbsp;arbitrator appointed in accordance with such rules. The arbitrator may grant injunctive or other relief in such dispute or controversy. The decision of
the arbitrator shall be final, conclusive and binding on the parties to the arbitration. Judgment may be entered on the arbitrator&#146;s decision in any court of competent jurisdiction. The parties agree that, any provision of applicable law
notwithstanding, they will not request, and the arbitrator shall have no authority to award, punitive or exemplary damages against either party. The costs of the arbitration, including administrative and arbitrator&#146;s fees, shall be shared
equally by the parties. Each party shall bear the cost of its own attorneys&#146; fees and expert witness fees. </P>
 <p STYLE="margin-top:0pt;margin-bottom:0pt ; font-size:8pt">&nbsp;</P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">-4- </P>

</DIV></Center>


<p style="margin-top:1em; margin-bottom:0em; page-break-before:always">
<HR SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>8.</B>&nbsp;&nbsp;&nbsp;&nbsp;<B><U>CONFLICTING OBLIGATIONS</U></B>. Consultant hereby certifies that he
or she has no outstanding agreement or obligation that is in conflict with any of the provisions of this Agreement, or that would preclude Consultant from complying with the provisions hereof, and further certifies that Consultant will not enter
into any such conflicting agreement during the term of this Agreement. Subject to written waivers that may be provided by the Company upon request, which shall not be unreasonably withheld, Consultant agrees that, during the term of this Agreement,
Consultant will not directly or indirectly (i)&nbsp;provide any services in the Field of Interest to any other business or commercial entity, (ii)&nbsp;provide any services for any company that is competitive with the Company and shall list in
<U>Exhibit B</U> hereto any other companies for whom Consultant is providing services (&#147;<U>Outside Companies</U>&#148;), or (iii)&nbsp;participate in the formation of any business or commercial entity in the Field of Interest or otherwise
competitive with the Company. The &#147;Field of Interest&#148; means the research, development, manufacturing or commercialization of human Factor VIIa or Factor IX products, or varients thereof, or of complement-related products or product
candidates that would compete with products or product candidates that the Company has in development as of the date of the Effective Date. Without limiting the foregoing, Consultant agrees to use his or her best efforts (A)&nbsp;to segregate
Consultant&#146;s Services performed under this Agreement from Consultant&#146;s work done for the Outside Companies so as to minimize any questions of disclosure of, or rights under, any inventions, (B)&nbsp;to notify the CEO of the Company if at
any time the Consultant believes that such questions may result from his or her performance under this Agreement and (C)&nbsp;to assist the Company in fairly resolving any questions in this regard which may arise. The Services performed hereunder
will not be conducted on time that is required to be devoted to any other third party. The Consultant shall not use the funding, resources and facilities of any other third party, without the prior written consent of the Company, to perform Services
hereunder and shall not perform the Services hereunder in any manner that would give any third party rights or access to the product of such Services. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>9.</B>&nbsp;&nbsp;&nbsp;&nbsp;<B><U>GENERAL</U></B>. This Agreement (together with the Exhibits hereto) is the sole agreement and understanding between
Company and Consultant concerning the subject matter hereof, and it supersedes all prior agreements and understandings with respect to such matter. Any required notice shall be given in writing by customary means with receipt confirmed at the
address of each party set forth below, or to such other address as either party may substitute by written notice to the other. Consultant shall not subcontract any portion of Consultant&#146;s duties under this Agreement without the prior written
consent of Company. Neither this Agreement nor any right hereunder or interest herein may be assigned or transferred by Consultant without the express written consent of Company. Company may assign this Agreement to any entity that succeeds to
substantially all of the business or assets of Company. This Agreement shall be governed by the laws of the State of California, without reference to its conflicts of law principles. This Agreement may only be amended or modified by a writing signed
by both parties. Waiver of any term or provision of this Agreement or forbearance to enforce any term or provision by either party shall not constitute a waiver as to any subsequent breach or failure of the same term or provision or a waiver of any
other term or provision of this Agreement. In the event that any provision of this Agreement becomes or is declared by a court of competent jurisdiction to be illegal, unenforceable or void, this Agreement shall continue in full force and effect
without said provision, provided that no such severability shall be effective if it materially changes the economic benefit of this Agreement to either Company or Consultant. </P>
 <p STYLE="margin-top:0pt;margin-bottom:0pt ; font-size:8pt">&nbsp;</P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">-5- </P>

</DIV></Center>


<p style="margin-top:1em; margin-bottom:0em; page-break-before:always">
<HR SIZE="3" style="COLOR:#999999" WIDTH="100%" ALIGN="CENTER">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; text-indent:4%; font-size:10pt; font-family:Times New Roman">IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the Effective
Date. </P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:10pt">


<TR>

<TD WIDTH="9%"></TD>

<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="41%"></TD>

<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="4%"></TD>

<TD VALIGN="bottom"></TD>
<TD></TD>

<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="42%"></TD></TR>


<TR STYLE="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top" COLSPAN="3"><B>CATALYST BIOSCIENCES, INC.</B></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD COLSPAN="3" VALIGN="top"></TD></TR>
<TR STYLE="font-size:1pt">
<TD HEIGHT="16"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD>
<TD HEIGHT="16" COLSPAN="2"></TD></TR>
<TR STYLE="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top">By:</TD>
<TD VALIGN="bottom" STYLE=" BORDER-BOTTOM:1px solid #000000">&nbsp;</TD>
<TD VALIGN="top" STYLE="BORDER-BOTTOM:1px solid #000000">/s/ Nassim Usman, Ph.D.</TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom" STYLE=" BORDER-BOTTOM:1px solid #000000">&nbsp;</TD>
<TD VALIGN="top" STYLE="BORDER-BOTTOM:1px solid #000000">/s/ Clinton Musil</TD></TR>
<TR STYLE="font-size:1pt">
<TD HEIGHT="5"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD></TR>
<TR STYLE="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top">Print&nbsp;Name:</TD>
<TD VALIGN="bottom" STYLE=" BORDER-BOTTOM:1px solid #000000">&nbsp;</TD>
<TD VALIGN="top" STYLE="BORDER-BOTTOM:1px solid #000000">Nassim Usman, Ph.D.</TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom" STYLE=" BORDER-BOTTOM:1px solid #000000">&nbsp;</TD>
<TD VALIGN="top" STYLE="BORDER-BOTTOM:1px solid #000000">Clinton Musil</TD></TR>
<TR STYLE="font-size:1pt">
<TD HEIGHT="5"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD>
<TD HEIGHT="5" COLSPAN="2"></TD></TR>
<TR STYLE="page-break-inside:avoid ; font-family:Times New Roman; font-size:10pt">
<TD VALIGN="top">Title:</TD>
<TD VALIGN="bottom" STYLE=" BORDER-BOTTOM:1px solid #000000">&nbsp;</TD>
<TD VALIGN="top" STYLE="BORDER-BOTTOM:1px solid #000000">President&nbsp;&amp; CEO</TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top"></TD></TR>
</TABLE> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">C<SMALL>ATALYST</SMALL> B<SMALL>IOSCIENCES</SMALL>, I<SMALL>NC</SMALL>. </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center">C<SMALL>ONSULTING</SMALL> A<SMALL>GREEMENT</SMALL> </P>
</DIV></Center>

</BODY></HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>3
<FILENAME>d230267dex991.htm
<DESCRIPTION>EX-99.1
<TEXT>
<HTML><HEAD>
<TITLE>EX-99.1</TITLE>
</HEAD>
 <BODY BGCOLOR="WHITE">

<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="right"><B>Exhibit 99.1 </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<P STYLE="margin-top:0pt;margin-bottom:0pt">


<IMG SRC="g230267g56b93.jpg" ALT="LOGO">
 </P> <P STYLE="margin-top:24pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>Catalyst Biosciences Announces Chief Financial Officer Transition </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>SOUTH SAN FRANCISCO, Calif. &#150; October</B><B></B><B>&nbsp;13, 2021</B> &#150; Catalyst Biosciences, Inc. (NASDAQ: CBIO) today announced that its chief
financial officer,&nbsp;Clinton Musil, has resigned for personal reasons effective October&nbsp;29, 2021. Seline Miller, the Company&#146;s controller, has been promoted to senior vice president, finance and will serve as interim chief financial and
principal accounting officer while the Company initiates a search for a successor. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">&#147;I would like to thank Clinton for his many contributions as a
member of our executive leadership team as we advance several programs in our Protease Medicines platform,&#148; said Nassim Usman, Ph.D., chief executive officer of Catalyst. &#147;We wish Clinton the best in his next endeavor.&#148; </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Mr.&nbsp;Musil added, &#147;I am proud to have been part of advancing Catalyst&#146;s Protease Medicines programs and I look forward to following the
Company&#146;s progress in the years ahead. I&#146;d like to say thank you to all my fellow employees for their hard work and dedication to the Company&#146;s mission.&#148; </P>
<P STYLE="margin-top:18pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>About Catalyst Biosciences, the Protease Medicines company </B></P>
<P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Catalyst is a research and clinical development biopharmaceutical company focused on addressing unmet medical needs in rare disorders of the complement and
coagulation systems. Our protease engineering platform has generated two late-stage clinical programs, including MarzAA, a subcutaneously (SQ) administered next-generation engineered coagulation Factor VIIa (FVIIa) for the treatment of episodic
bleeding in subjects with rare bleeding disorders. Our complement pipeline includes a preclinical <FONT STYLE="white-space:nowrap">C3-degrader</FONT> program licensed to Biogen for dry <FONT STYLE="white-space:nowrap">age-related</FONT> macular
degeneration, an improved complement factor I protease for SQ replacement therapy in patients with CFI deficiency and proteases from our ProTUNE<SUP STYLE="font-size:85%; vertical-align:top">&#153;</SUP>
<FONT STYLE="white-space:nowrap">C3b-C4b</FONT> degrader and ImmunoTUNE<SUP STYLE="font-size:85%; vertical-align:top">&#153;</SUP> <FONT STYLE="white-space:nowrap">C3a-C5a</FONT> degrader platforms designed to target specific disorders of the
complement or inflammatory pathways as well as other complement programs in development. </P> <P STYLE="margin-top:18pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>Forward-Looking Statements </B></P>
<P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">This press release contains forward-looking statements that involve substantial risks and uncertainties. Forward-looking statements include, without
limitation, statements about the product candidates of&nbsp;Catalyst Biosciences, Inc.&nbsp;(the &#147;Company&#148;) and the benefits of its protease engineering platform. Actual results or events could differ materially from the plans, intentions,
expectations and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially, including, but not limited to, the risk that clinical trials and <FONT
STYLE="white-space:nowrap">pre-clinical</FONT> studies may be delayed as a result of <FONT STYLE="white-space:nowrap">COVID-19,</FONT> competitive products and other factors, that clinical trials may not have satisfactory outcomes, that the
Company&#146;s complement degraders are not yet in human clinical trials and will require additional manufacturing validation and <FONT STYLE="white-space:nowrap">pre-clinical</FONT> testing before entering human clinical trials, that the Company
may need to raise additional capital, and other risks described in the &#147;Risk Factors&#148; section of the Company&#146;s Annual Report on Form <FONT STYLE="white-space:nowrap">10-K</FONT> filed with the&nbsp;Securities and Exchange
Commission&nbsp;(the &#147;SEC&#148;) on March&nbsp;4, 2021, the Quarterly Report on Form <FONT STYLE="white-space:nowrap">10-Q</FONT> filed with the SEC on&nbsp;August 5, 2021, and in other filings filed from time to time with the&nbsp;SEC. The
Company does not assume any obligation to update any forward-looking statements, except as required by law. </P> <P STYLE="margin-top:18pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>Contact: </B></P>
<P STYLE="margin-top:6pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Ana Kapor </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Catalyst Biosciences, Inc. </P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><U>investors@catbio.com </U></P>
</DIV></Center>

</BODY></HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.SCH
<SEQUENCE>4
<FILENAME>cbio-20211007.xsd
<DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA
<TEXT>
<XBRL>
<?xml version="1.0" encoding="us-ascii"?>
<!-- DFIN - https://www.dfinsolutions.com/ -->
<!-- CTU Version: Release master Build:20210621.2 -->
<!-- Creation date: 10/14/2021 12:14:52 AM Eastern Time -->
<!-- Copyright (c) 2021 Donnelley Financial Solutions, Inc. All Rights Reserved. -->
<xsd:schema
  xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric"
  xmlns:num="http://www.xbrl.org/dtr/type/numeric"
  xmlns:us-types="http://fasb.org/us-types/2020-01-31"
  xmlns:cbio="http://www.catalystbiosciences.com/20211007"
  xmlns:dei="http://xbrl.sec.gov/dei/2020-01-31"
  xmlns:xbrli="http://www.xbrl.org/2003/instance"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:xlink="http://www.w3.org/1999/xlink"
  xmlns:xbrldt="http://xbrl.org/2005/xbrldt"

  attributeFormDefault="unqualified"
  elementFormDefault="qualified"
  targetNamespace="http://www.catalystbiosciences.com/20211007"
  xmlns:xsd="http://www.w3.org/2001/XMLSchema">
    <xsd:import schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" namespace="http://www.xbrl.org/2003/instance" />
    <xsd:import schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" namespace="http://www.xbrl.org/2003/linkbase" />
    <xsd:import schemaLocation="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd" namespace="http://xbrl.sec.gov/dei/2020-01-31" />
    <xsd:import schemaLocation="http://www.xbrl.org/dtr/type/numeric-2009-12-16.xsd" namespace="http://www.xbrl.org/dtr/type/numeric" />
    <xsd:import schemaLocation="http://www.xbrl.org/dtr/type/nonNumeric-2009-12-16.xsd" namespace="http://www.xbrl.org/dtr/type/non-numeric" />

    <xsd:import schemaLocation="https://xbrl.sec.gov/naics/2017/naics-2017-01-31.xsd" namespace="http://xbrl.sec.gov/naics/2017-01-31" />
    <xsd:import schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd" namespace="http://xbrl.org/2005/xbrldt" />
  <xsd:annotation>
    <xsd:appinfo>
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="cbio-20211007_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:title="Label Links, all" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="cbio-20211007_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:title="Presentation Links, all" xlink:type="simple" />
      <link:roleType roleURI="http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation" id="Role_DocumentDocumentAndEntityInformation">
        <link:definition>100000 - Document - Document and Entity Information</link:definition>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xsd:appinfo>
  </xsd:annotation>
</xsd:schema>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.LAB
<SEQUENCE>5
<FILENAME>cbio-20211007_lab.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="us-ascii" standalone="yes"?>
<!-- DFIN - https://www.dfinsolutions.com/ -->
<!-- CTU Version: Release master Build:20210621.2 -->
<!-- Creation date: 10/14/2021 12:14:52 AM Eastern Time -->
<!-- Copyright (c) 2021 Donnelley Financial Solutions, Inc. All Rights Reserved. -->
<link:linkbase
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:xlink="http://www.w3.org/1999/xlink"
  xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
  xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:labelLink xlink:role="http://www.xbrl.org/2003/role/link" xlink:type="extended">
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CoverAbstract" xlink:type="locator" xlink:label="dei_CoverAbstract" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CoverAbstract" xlink:to="dei_CoverAbstract_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_CoverAbstract_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Cover [Abstract]</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_CoverAbstract_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Cover [Abstract]</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag" xlink:type="locator" xlink:label="dei_AmendmentFlag" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_AmendmentFlag" xlink:to="dei_AmendmentFlag_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_AmendmentFlag_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Amendment Flag</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_AmendmentFlag_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Amendment Flag</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey" xlink:type="locator" xlink:label="dei_EntityCentralIndexKey" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityCentralIndexKey" xlink:to="dei_EntityCentralIndexKey_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Central Index Key</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityCentralIndexKey_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Central Index Key</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType" xlink:type="locator" xlink:label="dei_DocumentType" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentType" xlink:to="dei_DocumentType_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_DocumentType_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Document Type</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_DocumentType_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Type</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate" xlink:type="locator" xlink:label="dei_DocumentPeriodEndDate" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_DocumentPeriodEndDate" xlink:to="dei_DocumentPeriodEndDate_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Document Period End Date</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_DocumentPeriodEndDate_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Document Period End Date</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName" xlink:type="locator" xlink:label="dei_EntityRegistrantName" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityRegistrantName" xlink:to="dei_EntityRegistrantName_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityRegistrantName_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Registrant Name</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityRegistrantName_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Registrant Name</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:type="locator" xlink:label="dei_EntityIncorporationStateCountryCode" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityIncorporationStateCountryCode" xlink:to="dei_EntityIncorporationStateCountryCode_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Incorporation State Country Code</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityIncorporationStateCountryCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Incorporation State Country Code</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber" xlink:type="locator" xlink:label="dei_EntityFileNumber" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityFileNumber" xlink:to="dei_EntityFileNumber_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityFileNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity File Number</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityFileNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity File Number</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:type="locator" xlink:label="dei_EntityTaxIdentificationNumber" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityTaxIdentificationNumber" xlink:to="dei_EntityTaxIdentificationNumber_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Tax Identification Number</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityTaxIdentificationNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Tax Identification Number</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1" xlink:type="locator" xlink:label="dei_EntityAddressAddressLine1" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine1" xlink:to="dei_EntityAddressAddressLine1_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressAddressLine1_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, Address Line One</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressAddressLine1_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, Address Line One</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine2" xlink:type="locator" xlink:label="dei_EntityAddressAddressLine2" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressAddressLine2" xlink:to="dei_EntityAddressAddressLine2_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressAddressLine2_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, Address Line Two</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressAddressLine2_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, Address Line Two</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown" xlink:type="locator" xlink:label="dei_EntityAddressCityOrTown" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressCityOrTown" xlink:to="dei_EntityAddressCityOrTown_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressCityOrTown_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, City or Town</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressCityOrTown_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, City or Town</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:type="locator" xlink:label="dei_EntityAddressStateOrProvince" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressStateOrProvince" xlink:to="dei_EntityAddressStateOrProvince_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressStateOrProvince_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, State or Province</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressStateOrProvince_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, State or Province</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:type="locator" xlink:label="dei_EntityAddressPostalZipCode" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityAddressPostalZipCode" xlink:to="dei_EntityAddressPostalZipCode_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressPostalZipCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Address, Postal Zip Code</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityAddressPostalZipCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Address, Postal Zip Code</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode" xlink:type="locator" xlink:label="dei_CityAreaCode" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_CityAreaCode" xlink:to="dei_CityAreaCode_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_CityAreaCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">City Area Code</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_CityAreaCode_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">City Area Code</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber" xlink:type="locator" xlink:label="dei_LocalPhoneNumber" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_LocalPhoneNumber" xlink:to="dei_LocalPhoneNumber_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_LocalPhoneNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Local Phone Number</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_LocalPhoneNumber_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Local Phone Number</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications" xlink:type="locator" xlink:label="dei_WrittenCommunications" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_WrittenCommunications" xlink:to="dei_WrittenCommunications_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_WrittenCommunications_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Written Communications</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_WrittenCommunications_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Written Communications</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial" xlink:type="locator" xlink:label="dei_SolicitingMaterial" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SolicitingMaterial" xlink:to="dei_SolicitingMaterial_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_SolicitingMaterial_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Soliciting Material</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_SolicitingMaterial_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Soliciting Material</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer" xlink:type="locator" xlink:label="dei_PreCommencementTenderOffer" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementTenderOffer" xlink:to="dei_PreCommencementTenderOffer_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_PreCommencementTenderOffer_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Pre Commencement Tender Offer</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_PreCommencementTenderOffer_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Pre Commencement Tender Offer</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:type="locator" xlink:label="dei_PreCommencementIssuerTenderOffer" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_PreCommencementIssuerTenderOffer" xlink:to="dei_PreCommencementIssuerTenderOffer_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_PreCommencementIssuerTenderOffer_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Pre Commencement Issuer Tender Offer</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_PreCommencementIssuerTenderOffer_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Pre Commencement Issuer Tender Offer</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle" xlink:type="locator" xlink:label="dei_Security12bTitle" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_Security12bTitle" xlink:to="dei_Security12bTitle_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_Security12bTitle_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Security 12b Title</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_Security12bTitle_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Security 12b Title</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol" xlink:type="locator" xlink:label="dei_TradingSymbol" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_TradingSymbol" xlink:to="dei_TradingSymbol_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_TradingSymbol_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Trading Symbol</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_TradingSymbol_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Trading Symbol</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName" xlink:type="locator" xlink:label="dei_SecurityExchangeName" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_SecurityExchangeName" xlink:to="dei_SecurityExchangeName_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_SecurityExchangeName_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Security Exchange Name</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_SecurityExchangeName_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Security Exchange Name</link:label>
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:type="locator" xlink:label="dei_EntityEmergingGrowthCompany" />
    <link:labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="dei_EntityEmergingGrowthCompany" xlink:to="dei_EntityEmergingGrowthCompany_lbl" />
    <link:label xml:lang="en-US" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label">Entity Emerging Growth Company</link:label>
    <link:label xml:lang="en-US" xlink:label="dei_EntityEmergingGrowthCompany_lbl" xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel">Entity Emerging Growth Company</link:label>
  </link:labelLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.PRE
<SEQUENCE>6
<FILENAME>cbio-20211007_pre.xml
<DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE
<TEXT>
<XBRL>
<?xml version="1.0" encoding="us-ascii" standalone="yes"?>
<!-- DFIN - https://www.dfinsolutions.com/ -->
<!-- CTU Version: Release master Build:20210621.2 -->
<!-- Creation date: 10/14/2021 12:14:52 AM Eastern Time -->
<!-- Copyright (c) 2021 Donnelley Financial Solutions, Inc. All Rights Reserved. -->
<link:linkbase
    xmlns:link="http://www.xbrl.org/2003/linkbase"
    xmlns:xlink="http://www.w3.org/1999/xlink"
    xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xmlns:xbrldt="http://xbrl.org/2005/xbrldt"
    xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation" xlink:href="cbio-20211007.xsd#Role_DocumentDocumentAndEntityInformation" xlink:type="simple" />
  <link:presentationLink xlink:type="extended" xlink:role="http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation">
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CoverAbstract" xlink:type="locator" xlink:label="dei_CoverAbstract" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag" xlink:type="locator" xlink:label="dei_AmendmentFlag" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_AmendmentFlag" order="22.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey" xlink:type="locator" xlink:label="dei_EntityCentralIndexKey" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityCentralIndexKey" order="23.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType" xlink:type="locator" xlink:label="dei_DocumentType" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_DocumentType" order="25.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate" xlink:type="locator" xlink:label="dei_DocumentPeriodEndDate" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_DocumentPeriodEndDate" order="26.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName" xlink:type="locator" xlink:label="dei_EntityRegistrantName" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityRegistrantName" order="27.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode" xlink:type="locator" xlink:label="dei_EntityIncorporationStateCountryCode" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityIncorporationStateCountryCode" order="28.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber" xlink:type="locator" xlink:label="dei_EntityFileNumber" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityFileNumber" order="29.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber" xlink:type="locator" xlink:label="dei_EntityTaxIdentificationNumber" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityTaxIdentificationNumber" order="30.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1" xlink:type="locator" xlink:label="dei_EntityAddressAddressLine1" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityAddressAddressLine1" order="31.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine2" xlink:type="locator" xlink:label="dei_EntityAddressAddressLine2" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityAddressAddressLine2" order="32.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown" xlink:type="locator" xlink:label="dei_EntityAddressCityOrTown" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityAddressCityOrTown" order="33.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince" xlink:type="locator" xlink:label="dei_EntityAddressStateOrProvince" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityAddressStateOrProvince" order="34.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode" xlink:type="locator" xlink:label="dei_EntityAddressPostalZipCode" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityAddressPostalZipCode" order="35.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode" xlink:type="locator" xlink:label="dei_CityAreaCode" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_CityAreaCode" order="36.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber" xlink:type="locator" xlink:label="dei_LocalPhoneNumber" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_LocalPhoneNumber" order="37.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_WrittenCommunications" xlink:type="locator" xlink:label="dei_WrittenCommunications" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_WrittenCommunications" order="38.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SolicitingMaterial" xlink:type="locator" xlink:label="dei_SolicitingMaterial" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_SolicitingMaterial" order="39.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementTenderOffer" xlink:type="locator" xlink:label="dei_PreCommencementTenderOffer" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_PreCommencementTenderOffer" order="40.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_PreCommencementIssuerTenderOffer" xlink:type="locator" xlink:label="dei_PreCommencementIssuerTenderOffer" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_PreCommencementIssuerTenderOffer" order="41.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle" xlink:type="locator" xlink:label="dei_Security12bTitle" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_Security12bTitle" order="42.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol" xlink:type="locator" xlink:label="dei_TradingSymbol" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_TradingSymbol" order="43.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_SecurityExchangeName" xlink:type="locator" xlink:label="dei_SecurityExchangeName" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_SecurityExchangeName" order="44.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:type="locator" xlink:label="dei_EntityEmergingGrowthCompany" />
    <link:presentationArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="dei_CoverAbstract" xlink:to="dei_EntityEmergingGrowthCompany" order="45.001" priority="2" use="optional" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" />
  </link:presentationLink>
</link:linkbase>
</XBRL>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g230267g56b93.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 g230267g56b93.jpg
M_]C_X  02D9)1@ ! 0$ 2 !(  #_X0!:17AI9@  34T *@    @ !0,!  4
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M 0$! 0$!         0(#! 4&!P@)"@O_Q "U$0 " 0($! ,$!P4$!  ! G<
M 0(#$00%(3$&$D%1!V%Q$R(R@0@40I&AL<$)(S-2\!5B<M$*%B0TX27Q%Q@9
M&B8G*"DJ-38W.#DZ0T1%1D=(24I35%565UA96F-D969G:&EJ<W1U=G=X>7J"
M@X2%AH>(B8J2DY25EI>8F9JBHZ2EIJ>HJ:JRL[2UMK>XN;K"P\3%QL?(R<K2
MT]35UM?8V=KBX^3EYN?HZ>KR\_3U]O?X^?K_V@ , P$  A$#$0 _ /?Z***
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M_$Z1L_\ PD-O\H)Q]A7_ !INF?\ $K\8:CIQX@OE%[ ,<;^D@^I//TKH9_\
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MVUQ&/NM=6YW@>Y!Y^IJ:PT"9=234]5OFOKR,$0C8$CA!Z[5]?>@#=KFO ?\
MR*T?_7:7_P!#-=+67X>TEM$TE;)YA*5=FW!<=3F@#3) !). .IKG=2O3=3;5
M)\M> /7WK9O()KA/+20(AZ^IK/\ [#;_ )[#\J\[&JO4]RG'0Z\,Z</>D]3#
MN)TMH&ED/RK^I]*R]/T:^\0733L/+A)YD(X'L/6NM'AF"69)+R5IE0Y6-1M7
M\>YK;1$C14C4*BC 51@"M,'A?8QYI?$R<17]H[+8J:;I5KI4 BMTY(^9S]YO
MK7.^*='\MSJ$"_*Q_>@=CZ_C_GK77TV2-)8VCD4,C## ]Q6F+PT<12<'\O46
M&Q$J%137S/)I(UEC*,.#6++$T,A1NH_6NNUG2WTN^:/DQ-\T;>H_QK%O+?SX
M\J/G7I[^U?&SA*G-PENC[/"UXM*2>C.M^'^J>=9RZ;(WS0GS(_\ =/4?@?YU
MVE>,:)J+:3J]O=C.U&PX]5/!'Y5[,CK(BNA#*PR".XKZ?*L1[2CR/>/Y=#YW
M.\+[+$>T6TM?GU%HHHKU#QCEI]7\07/B/4--TJ+3?+LQ&2USO!.]<_P_C1/J
M_B/1XOM>K6-C/9J1YK63MOC'KANM9ZZJ^E^.]>*:;>WOF);Y%K&&VX3OR/6C
M7O$L][8'3CI=WIR7A\E[J_CV1QJ>O3//Y4 ;^N:T^G:?9W=H(Y5N+B.,%LXV
MMGD5)KFMKI$<,<4#7-[<MLM[=3@N>Y)[ =S61XKMTM/#^D6T9)2&\MXU)[@
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#/__9

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>8
<FILENAME>d230267d8k_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version="1.0" encoding="utf-8"?>
<xbrl
  xmlns="http://www.xbrl.org/2003/instance"
  xmlns:dei="http://xbrl.sec.gov/dei/2020-01-31"
  xmlns:link="http://www.xbrl.org/2003/linkbase"
  xmlns:xlink="http://www.w3.org/1999/xlink">
    <link:schemaRef xlink:href="cbio-20211007.xsd" xlink:type="simple"/>
    <context id="duration_2021-10-07_to_2021-10-07">
        <entity>
            <identifier scheme="http://www.sec.gov/CIK">0001124105</identifier>
        </entity>
        <period>
            <startDate>2021-10-07</startDate>
            <endDate>2021-10-07</endDate>
        </period>
    </context>
    <dei:AmendmentFlag contextRef="duration_2021-10-07_to_2021-10-07">false</dei:AmendmentFlag>
    <dei:EntityCentralIndexKey
      contextRef="duration_2021-10-07_to_2021-10-07"
      id="Hidden_dei_EntityCentralIndexKey">0001124105</dei:EntityCentralIndexKey>
    <dei:DocumentType contextRef="duration_2021-10-07_to_2021-10-07">8-K</dei:DocumentType>
    <dei:DocumentPeriodEndDate contextRef="duration_2021-10-07_to_2021-10-07">2021-10-07</dei:DocumentPeriodEndDate>
    <dei:EntityRegistrantName contextRef="duration_2021-10-07_to_2021-10-07">CATALYST BIOSCIENCES, INC.</dei:EntityRegistrantName>
    <dei:EntityIncorporationStateCountryCode contextRef="duration_2021-10-07_to_2021-10-07">DE</dei:EntityIncorporationStateCountryCode>
    <dei:EntityFileNumber contextRef="duration_2021-10-07_to_2021-10-07">000-51173</dei:EntityFileNumber>
    <dei:EntityTaxIdentificationNumber contextRef="duration_2021-10-07_to_2021-10-07">56-2020050</dei:EntityTaxIdentificationNumber>
    <dei:EntityAddressAddressLine1 contextRef="duration_2021-10-07_to_2021-10-07">611 Gateway Blvd</dei:EntityAddressAddressLine1>
    <dei:EntityAddressAddressLine2 contextRef="duration_2021-10-07_to_2021-10-07">Suite 710</dei:EntityAddressAddressLine2>
    <dei:EntityAddressCityOrTown contextRef="duration_2021-10-07_to_2021-10-07">South San Francisco</dei:EntityAddressCityOrTown>
    <dei:EntityAddressStateOrProvince contextRef="duration_2021-10-07_to_2021-10-07">CA</dei:EntityAddressStateOrProvince>
    <dei:EntityAddressPostalZipCode contextRef="duration_2021-10-07_to_2021-10-07">94080</dei:EntityAddressPostalZipCode>
    <dei:CityAreaCode contextRef="duration_2021-10-07_to_2021-10-07">(650)</dei:CityAreaCode>
    <dei:LocalPhoneNumber contextRef="duration_2021-10-07_to_2021-10-07">871-0761</dei:LocalPhoneNumber>
    <dei:WrittenCommunications contextRef="duration_2021-10-07_to_2021-10-07">false</dei:WrittenCommunications>
    <dei:SolicitingMaterial contextRef="duration_2021-10-07_to_2021-10-07">false</dei:SolicitingMaterial>
    <dei:PreCommencementTenderOffer contextRef="duration_2021-10-07_to_2021-10-07">false</dei:PreCommencementTenderOffer>
    <dei:PreCommencementIssuerTenderOffer contextRef="duration_2021-10-07_to_2021-10-07">false</dei:PreCommencementIssuerTenderOffer>
    <dei:Security12bTitle contextRef="duration_2021-10-07_to_2021-10-07">Common Stock</dei:Security12bTitle>
    <dei:TradingSymbol contextRef="duration_2021-10-07_to_2021-10-07">CBIO</dei:TradingSymbol>
    <dei:SecurityExchangeName contextRef="duration_2021-10-07_to_2021-10-07">NASDAQ</dei:SecurityExchangeName>
    <dei:EntityEmergingGrowthCompany contextRef="duration_2021-10-07_to_2021-10-07">false</dei:EntityEmergingGrowthCompany>
</xbrl>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>9
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<html>
<head>
<title></title>
<link rel="stylesheet" type="text/css" href="report.css">
<script type="text/javascript" src="Show.js">/* Do Not Remove This Comment */</script><script type="text/javascript">
							function toggleNextSibling (e) {
							if (e.nextSibling.style.display=='none') {
							e.nextSibling.style.display='block';
							} else { e.nextSibling.style.display='none'; }
							}</script>
</head>
<body>
<span style="display: none;">v3.21.2</span><table class="report" border="0" cellspacing="2" id="idm140117220001736">
<tr>
<th class="tl" colspan="1" rowspan="1"><div style="width: 200px;"><strong>Document and Entity Information<br></strong></div></th>
<th class="th"><div>Oct. 07, 2021</div></th>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_CoverAbstract', window );"><strong>Cover [Abstract]</strong></a></td>
<td class="text">&#160;<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_AmendmentFlag', window );">Amendment Flag</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityCentralIndexKey', window );">Entity Central Index Key</a></td>
<td class="text">0001124105<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentType', window );">Document Type</a></td>
<td class="text">8-K<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_DocumentPeriodEndDate', window );">Document Period End Date</a></td>
<td class="text">Oct.  07,  2021<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityRegistrantName', window );">Entity Registrant Name</a></td>
<td class="text">CATALYST BIOSCIENCES, INC.<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityIncorporationStateCountryCode', window );">Entity Incorporation State Country Code</a></td>
<td class="text">DE<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityFileNumber', window );">Entity File Number</a></td>
<td class="text">000-51173<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityTaxIdentificationNumber', window );">Entity Tax Identification Number</a></td>
<td class="text">56-2020050<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressAddressLine1', window );">Entity Address, Address Line One</a></td>
<td class="text">611 Gateway Blvd<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressAddressLine2', window );">Entity Address, Address Line Two</a></td>
<td class="text">Suite 710<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressCityOrTown', window );">Entity Address, City or Town</a></td>
<td class="text">South San Francisco<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressStateOrProvince', window );">Entity Address, State or Province</a></td>
<td class="text">CA<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityAddressPostalZipCode', window );">Entity Address, Postal Zip Code</a></td>
<td class="text">94080<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_CityAreaCode', window );">City Area Code</a></td>
<td class="text">(650)<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_LocalPhoneNumber', window );">Local Phone Number</a></td>
<td class="text">871-0761<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_WrittenCommunications', window );">Written Communications</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SolicitingMaterial', window );">Soliciting Material</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_PreCommencementTenderOffer', window );">Pre Commencement Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_PreCommencementIssuerTenderOffer', window );">Pre Commencement Issuer Tender Offer</a></td>
<td class="text">false<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_Security12bTitle', window );">Security 12b Title</a></td>
<td class="text">Common Stock<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_TradingSymbol', window );">Trading Symbol</a></td>
<td class="text">CBIO<span></span>
</td>
</tr>
<tr class="re">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_SecurityExchangeName', window );">Security Exchange Name</a></td>
<td class="text">NASDAQ<span></span>
</td>
</tr>
<tr class="ro">
<td class="pl " style="border-bottom: 0px;" valign="top"><a class="a" href="javascript:void(0);" onclick="top.Show.showAR( this, 'defref_dei_EntityEmergingGrowthCompany', window );">Entity Emerging Growth Company</a></td>
<td class="text">false<span></span>
</td>
</tr>
</table>
<div style="display: none;">
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_AmendmentFlag">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_AmendmentFlag</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CityAreaCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Area code of city</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CityAreaCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_CoverAbstract">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Cover page.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_CoverAbstract</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:stringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentPeriodEndDate">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The end date of the period reflected on the cover page if a periodic report. For all other reports and registration statements containing historical data, it is the date up through which that historical data is presented.  If there is no historical data in the report, use the filing date. The format of the date is YYYY-MM-DD.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentPeriodEndDate</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:dateItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_DocumentType">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_DocumentType</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:submissionTypeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine1">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Address Line 1 such as Attn, Building Name, Street Name</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine1</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressAddressLine2">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Address Line 2 such as Street or Suite number</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressAddressLine2</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressCityOrTown">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the City or Town</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressCityOrTown</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressPostalZipCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Code for the postal or zip code</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressPostalZipCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityAddressStateOrProvince">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the state or province.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityAddressStateOrProvince</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:stateOrProvinceItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityCentralIndexKey">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityCentralIndexKey</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:centralIndexKeyItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityEmergingGrowthCompany">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Indicate if registrant meets the emerging growth company criteria.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityEmergingGrowthCompany</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityFileNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityFileNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:fileNumberItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityIncorporationStateCountryCode">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Two-character EDGAR code representing the state or country of incorporation.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityIncorporationStateCountryCode</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarStateCountryItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityRegistrantName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityRegistrantName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_EntityTaxIdentificationNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Regulation 12B<br> -Number 240<br> -Section 12<br> -Subsection b-2<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_EntityTaxIdentificationNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:employerIdItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_LocalPhoneNumber">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Local phone number for entity.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_LocalPhoneNumber</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:normalizedStringItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementIssuerTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 13e<br> -Subsection 4c<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementIssuerTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_PreCommencementTenderOffer">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 14d<br> -Subsection 2b<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_PreCommencementTenderOffer</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_Security12bTitle">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Title of a 12(b) registered security.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection b<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_Security12bTitle</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:securityTitleItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SecurityExchangeName">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Name of the Exchange on which a security is registered.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Number 240<br> -Section 12<br> -Subsection d1-1<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SecurityExchangeName</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:edgarExchangeCodeItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_SolicitingMaterial">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Exchange Act<br> -Section 14a<br> -Number 240<br> -Subsection 12<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_SolicitingMaterial</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_TradingSymbol">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Trading symbol of an instrument as listed on an exchange.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>No definition available.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_TradingSymbol</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>dei:tradingSymbolItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
<table border="0" cellpadding="0" cellspacing="0" class="authRefData" style="display: none;" id="defref_dei_WrittenCommunications">
<tr><td class="hide"><a style="color: white;" href="javascript:void(0);" onclick="top.Show.hideAR();">X</a></td></tr>
<tr><td><div class="body" style="padding: 2px;">
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">- Definition</a><div><p>Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.</p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ References</a><div style="display: none;"><p>Reference 1: http://www.xbrl.org/2003/role/presentationRef<br> -Publisher SEC<br> -Name Securities Act<br> -Number 230<br> -Section 425<br></p></div>
<a href="javascript:void(0);" onclick="top.Show.toggleNext( this );">+ Details</a><div style="display: none;"><table border="0" cellpadding="0" cellspacing="0">
<tr>
<td><strong> Name:</strong></td>
<td style="white-space:nowrap;">dei_WrittenCommunications</td>
</tr>
<tr>
<td style="padding-right: 4px;white-space:nowrap;"><strong> Namespace Prefix:</strong></td>
<td>dei_</td>
</tr>
<tr>
<td><strong> Data Type:</strong></td>
<td>xbrli:booleanItemType</td>
</tr>
<tr>
<td><strong> Balance Type:</strong></td>
<td>na</td>
</tr>
<tr>
<td><strong> Period Type:</strong></td>
<td>duration</td>
</tr>
</table></div>
</div></td></tr>
</table>
</div>
</body>
</html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EXCEL
<SEQUENCE>10
<FILENAME>Financial_Report.xlsx
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 Financial_Report.xlsx
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M=]W3CHG&K=!X#;[Q3X?#KHG&J]!TZVDF)_VN:Z3I%FA"1N/K>A(5M>5 TR
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M!Z.:60F]A%9JGZJ'-#ZH'C(*!?&Y'C[E>G@*-Y;&O%"N@GL!_]':-\*K^(+
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MU4#E/]O4#6CV#30<D05>,9FV-J/D3@H\W/[O#;#"Q([A[8N_ 5!+ P04
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MZJX#/%\H9=\;[BA<_B=C^!]02P,$%     @ FX9-4Y^@&_"Q @  X@P   T
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M':5_'<?VD-/IKV,BM'I;Z/EQ:%0*CMQC)8QQ8K3^-8+)#^Q^ %!+ P04
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MOS^QO-9.&G_FB^$_7G\!4$L! A0#%     @ FX9-4P=!36*!    L0   !
M             ( !     &1O8U!R;W!S+V%P<"YX;6Q02P$"% ,4    " ";
MADU3.,$QS>\    K @  $0              @ &O    9&]C4')O<',O8V]R
M92YX;6Q02P$"% ,4    " ";ADU3F5R<(Q &  "<)P  $P
M@ '- 0  >&PO=&AE;64O=&AE;64Q+GAM;%!+ 0(4 Q0    ( )N&35.#<LX_
M2 0  -40   8              " @0X(  !X;"]W;W)K<VAE971S+W-H965T
M,2YX;6Q02P$"% ,4    " ";ADU3GZ ;\+$"  #B#   #0
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:+GAM;%!+!08     "0 ) #X"  #L$P     !

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>11
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
// Edgar(tm) Renderer was created by staff of the U.S. Securities and Exchange Commission.  Data and content created by government employees within the scope of their employment are not subject to domestic copyright protection. 17 U.S.C. 105.
var Show={};Show.LastAR=null,Show.showAR=function(a,r,w){if(Show.LastAR)Show.hideAR();var e=a;while(e&&e.nodeName!='TABLE')e=e.nextSibling;if(!e||e.nodeName!='TABLE'){var ref=((window)?w.document:document).getElementById(r);if(ref){e=ref.cloneNode(!0);
e.removeAttribute('id');a.parentNode.appendChild(e)}}
if(e)e.style.display='block';Show.LastAR=e};Show.hideAR=function(){Show.LastAR.style.display='none'};Show.toggleNext=function(a){var e=a;while(e.nodeName!='DIV')e=e.nextSibling;if(!e.style){}else if(!e.style.display){}else{var d,p_;if(e.style.display=='none'){d='block';p='-'}else{d='none';p='+'}
e.style.display=d;if(a.textContent){a.textContent=p+a.textContent.substring(1)}else{a.innerText=p+a.innerText.substring(1)}}}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>12
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
/* Updated 2009-11-04 */
/* v2.2.0.24 */

/* DefRef Styles */
..report table.authRefData{
	background-color: #def;
	border: 2px solid #2F4497;
	font-size: 1em;
	position: absolute;
}

..report table.authRefData a {
	display: block;
	font-weight: bold;
}

..report table.authRefData p {
	margin-top: 0px;
}

..report table.authRefData .hide {
	background-color: #2F4497;
	padding: 1px 3px 0px 0px;
	text-align: right;
}

..report table.authRefData .hide a:hover {
	background-color: #2F4497;
}

..report table.authRefData .body {
	height: 150px;
	overflow: auto;
	width: 400px;
}

..report table.authRefData table{
	font-size: 1em;
}

/* Report Styles */
..pl a, .pl a:visited {
	color: black;
	text-decoration: none;
}

/* table */
..report {
	background-color: white;
	border: 2px solid #acf;
	clear: both;
	color: black;
	font: normal 8pt Helvetica, Arial, san-serif;
	margin-bottom: 2em;
}

..report hr {
	border: 1px solid #acf;
}

/* Top labels */
..report th {
	background-color: #acf;
	color: black;
	font-weight: bold;
	text-align: center;
}

..report th.void	{
	background-color: transparent;
	color: #000000;
	font: bold 10pt Helvetica, Arial, san-serif;
	text-align: left;
}

..report .pl {
	text-align: left;
	vertical-align: top;
	white-space: normal;
	width: 200px;
	white-space: normal; /* word-wrap: break-word; */
}

..report td.pl a.a {
	cursor: pointer;
	display: block;
	width: 200px;
	overflow: hidden;
}

..report td.pl div.a {
	width: 200px;
}

..report td.pl a:hover {
	background-color: #ffc;
}

/* Header rows... */
..report tr.rh {
	background-color: #acf;
	color: black;
	font-weight: bold;
}

/* Calendars... */
..report .rc {
	background-color: #f0f0f0;
}

/* Even rows... */
..report .re, .report .reu {
	background-color: #def;
}

..report .reu td {
	border-bottom: 1px solid black;
}

/* Odd rows... */
..report .ro, .report .rou {
	background-color: white;
}

..report .rou td {
	border-bottom: 1px solid black;
}

..report .rou table td, .report .reu table td {
	border-bottom: 0px solid black;
}

/* styles for footnote marker */
..report .fn {
	white-space: nowrap;
}

/* styles for numeric types */
..report .num, .report .nump {
	text-align: right;
	white-space: nowrap;
}

..report .nump {
	padding-left: 2em;
}

..report .nump {
	padding: 0px 0.4em 0px 2em;
}

/* styles for text types */
..report .text {
	text-align: left;
	white-space: normal;
}

..report .text .big {
	margin-bottom: 1em;
	width: 17em;
}

..report .text .more {
	display: none;
}

..report .text .note {
	font-style: italic;
	font-weight: bold;
}

..report .text .small {
	width: 10em;
}

..report sup {
	font-style: italic;
}

..report .outerFootnotes {
	font-size: 1em;
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>13
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
<XML>
<?xml version='1.0' encoding='utf-8'?>
<FilingSummary>
  <Version>3.21.2</Version>
  <ProcessingTime/>
  <ReportFormat>html</ReportFormat>
  <ContextCount>1</ContextCount>
  <ElementCount>96</ElementCount>
  <EntityCount>1</EntityCount>
  <FootnotesReported>false</FootnotesReported>
  <SegmentCount>0</SegmentCount>
  <ScenarioCount>0</ScenarioCount>
  <TuplesReported>false</TuplesReported>
  <UnitCount>0</UnitCount>
  <MyReports>
    <Report instance="d230267d8k.htm">
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <HtmlFileName>R1.htm</HtmlFileName>
      <LongName>100000 - Document - Document and Entity Information</LongName>
      <ReportType>Sheet</ReportType>
      <Role>http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation</Role>
      <ShortName>Document and Entity Information</ShortName>
      <MenuCategory>Cover</MenuCategory>
      <Position>1</Position>
    </Report>
    <Report>
      <IsDefault>false</IsDefault>
      <HasEmbeddedReports>false</HasEmbeddedReports>
      <LongName>All Reports</LongName>
      <ReportType>Book</ReportType>
      <ShortName>All Reports</ShortName>
    </Report>
  </MyReports>
  <InputFiles>
    <File doctype="8-K" original="d230267d8k.htm">d230267d8k.htm</File>
    <File>cbio-20211007.xsd</File>
    <File>cbio-20211007_lab.xml</File>
    <File>cbio-20211007_pre.xml</File>
    <File>d230267dex101.htm</File>
    <File>d230267dex991.htm</File>
  </InputFiles>
  <SupplementalFiles/>
  <BaseTaxonomies>
    <BaseTaxonomy>http://xbrl.sec.gov/dei/2020-01-31</BaseTaxonomy>
  </BaseTaxonomies>
  <HasPresentationLinkbase>true</HasPresentationLinkbase>
  <HasCalculationLinkbase>false</HasCalculationLinkbase>
</FilingSummary>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>JSON
<SEQUENCE>15
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
{
 "instance": {
  "d230267d8k.htm": {
   "axisCustom": 0,
   "axisStandard": 0,
   "contextCount": 1,
   "dts": {
    "inline": {
     "local": [
      "d230267d8k.htm"
     ]
    },
    "labelLink": {
     "local": [
      "cbio-20211007_lab.xml"
     ]
    },
    "presentationLink": {
     "local": [
      "cbio-20211007_pre.xml"
     ]
    },
    "schema": {
     "local": [
      "cbio-20211007.xsd"
     ],
     "remote": [
      "http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xl-2003-12-31.xsd",
      "http://www.xbrl.org/2003/xlink-2003-12-31.xsd",
      "https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd",
      "http://www.xbrl.org/2005/xbrldt-2005.xsd",
      "http://www.xbrl.org/dtr/type/nonNumeric-2009-12-16.xsd",
      "http://www.xbrl.org/dtr/type/numeric-2009-12-16.xsd",
      "https://xbrl.sec.gov/naics/2017/naics-2017-01-31.xsd",
      "http://www.xbrl.org/lrr/role/deprecated-2009-12-16.xsd"
     ]
    }
   },
   "elementCount": 24,
   "entityCount": 1,
   "hidden": {
    "http://xbrl.sec.gov/dei/2020-01-31": 2,
    "total": 2
   },
   "keyCustom": 0,
   "keyStandard": 96,
   "memberCustom": 0,
   "memberStandard": 0,
   "nsprefix": "cbio",
   "nsuri": "http://www.catalystbiosciences.com/20211007",
   "report": {
    "R1": {
     "firstAnchor": {
      "ancestors": [
       "p",
       "div",
       "div",
       "body",
       "html"
      ],
      "baseRef": "d230267d8k.htm",
      "contextRef": "duration_2021-10-07_to_2021-10-07",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     },
     "groupType": "document",
     "isDefault": "true",
     "longName": "100000 - Document - Document and Entity Information",
     "role": "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation",
     "shortName": "Document and Entity Information",
     "subGroupType": "",
     "uniqueAnchor": {
      "ancestors": [
       "p",
       "div",
       "div",
       "body",
       "html"
      ],
      "baseRef": "d230267d8k.htm",
      "contextRef": "duration_2021-10-07_to_2021-10-07",
      "decimals": null,
      "first": true,
      "lang": "en-US",
      "name": "dei:DocumentType",
      "reportCount": 1,
      "unique": true,
      "unitRef": null,
      "xsiNil": "false"
     }
    }
   },
   "segmentCount": 0,
   "tag": {
    "dei_AmendmentFlag": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.",
        "label": "Amendment Flag",
        "terseLabel": "Amendment Flag"
       }
      }
     },
     "localname": "AmendmentFlag",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_CityAreaCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Area code of city",
        "label": "City Area Code",
        "terseLabel": "City Area Code"
       }
      }
     },
     "localname": "CityAreaCode",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_CoverAbstract": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Cover page.",
        "label": "Cover [Abstract]",
        "terseLabel": "Cover [Abstract]"
       }
      }
     },
     "localname": "CoverAbstract",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "xbrltype": "stringItemType"
    },
    "dei_DocumentPeriodEndDate": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The end date of the period reflected on the cover page if a periodic report. For all other reports and registration statements containing historical data, it is the date up through which that historical data is presented.  If there is no historical data in the report, use the filing date. The format of the date is YYYY-MM-DD.",
        "label": "Document Period End Date",
        "terseLabel": "Document Period End Date"
       }
      }
     },
     "localname": "DocumentPeriodEndDate",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "dateItemType"
    },
    "dei_DocumentType": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.",
        "label": "Document Type",
        "terseLabel": "Document Type"
       }
      }
     },
     "localname": "DocumentType",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "submissionTypeItemType"
    },
    "dei_EntityAddressAddressLine1": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 1 such as Attn, Building Name, Street Name",
        "label": "Entity Address, Address Line One",
        "terseLabel": "Entity Address, Address Line One"
       }
      }
     },
     "localname": "EntityAddressAddressLine1",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressAddressLine2": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Address Line 2 such as Street or Suite number",
        "label": "Entity Address, Address Line Two",
        "terseLabel": "Entity Address, Address Line Two"
       }
      }
     },
     "localname": "EntityAddressAddressLine2",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressCityOrTown": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the City or Town",
        "label": "Entity Address, City or Town",
        "terseLabel": "Entity Address, City or Town"
       }
      }
     },
     "localname": "EntityAddressCityOrTown",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressPostalZipCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Code for the postal or zip code",
        "label": "Entity Address, Postal Zip Code",
        "terseLabel": "Entity Address, Postal Zip Code"
       }
      }
     },
     "localname": "EntityAddressPostalZipCode",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityAddressStateOrProvince": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the state or province.",
        "label": "Entity Address, State or Province",
        "terseLabel": "Entity Address, State or Province"
       }
      }
     },
     "localname": "EntityAddressStateOrProvince",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "stateOrProvinceItemType"
    },
    "dei_EntityCentralIndexKey": {
     "auth_ref": [
      "r5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.",
        "label": "Entity Central Index Key",
        "terseLabel": "Entity Central Index Key"
       }
      }
     },
     "localname": "EntityCentralIndexKey",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "centralIndexKeyItemType"
    },
    "dei_EntityEmergingGrowthCompany": {
     "auth_ref": [
      "r5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Indicate if registrant meets the emerging growth company criteria.",
        "label": "Entity Emerging Growth Company",
        "terseLabel": "Entity Emerging Growth Company"
       }
      }
     },
     "localname": "EntityEmergingGrowthCompany",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_EntityFileNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.",
        "label": "Entity File Number",
        "terseLabel": "Entity File Number"
       }
      }
     },
     "localname": "EntityFileNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "fileNumberItemType"
    },
    "dei_EntityIncorporationStateCountryCode": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Two-character EDGAR code representing the state or country of incorporation.",
        "label": "Entity Incorporation State Country Code",
        "terseLabel": "Entity Incorporation State Country Code"
       }
      }
     },
     "localname": "EntityIncorporationStateCountryCode",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "edgarStateCountryItemType"
    },
    "dei_EntityRegistrantName": {
     "auth_ref": [
      "r5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.",
        "label": "Entity Registrant Name",
        "terseLabel": "Entity Registrant Name"
       }
      }
     },
     "localname": "EntityRegistrantName",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_EntityTaxIdentificationNumber": {
     "auth_ref": [
      "r5"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.",
        "label": "Entity Tax Identification Number",
        "terseLabel": "Entity Tax Identification Number"
       }
      }
     },
     "localname": "EntityTaxIdentificationNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "employerIdItemType"
    },
    "dei_LocalPhoneNumber": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Local phone number for entity.",
        "label": "Local Phone Number",
        "terseLabel": "Local Phone Number"
       }
      }
     },
     "localname": "LocalPhoneNumber",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "normalizedStringItemType"
    },
    "dei_PreCommencementIssuerTenderOffer": {
     "auth_ref": [
      "r2"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.",
        "label": "Pre Commencement Issuer Tender Offer",
        "terseLabel": "Pre Commencement Issuer Tender Offer"
       }
      }
     },
     "localname": "PreCommencementIssuerTenderOffer",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_PreCommencementTenderOffer": {
     "auth_ref": [
      "r3"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.",
        "label": "Pre Commencement Tender Offer",
        "terseLabel": "Pre Commencement Tender Offer"
       }
      }
     },
     "localname": "PreCommencementTenderOffer",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_Security12bTitle": {
     "auth_ref": [
      "r0"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Title of a 12(b) registered security.",
        "label": "Security 12b Title",
        "terseLabel": "Security 12b Title"
       }
      }
     },
     "localname": "Security12bTitle",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "securityTitleItemType"
    },
    "dei_SecurityExchangeName": {
     "auth_ref": [
      "r1"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Name of the Exchange on which a security is registered.",
        "label": "Security Exchange Name",
        "terseLabel": "Security Exchange Name"
       }
      }
     },
     "localname": "SecurityExchangeName",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "edgarExchangeCodeItemType"
    },
    "dei_SolicitingMaterial": {
     "auth_ref": [
      "r4"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.",
        "label": "Soliciting Material",
        "terseLabel": "Soliciting Material"
       }
      }
     },
     "localname": "SolicitingMaterial",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    },
    "dei_TradingSymbol": {
     "auth_ref": [],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Trading symbol of an instrument as listed on an exchange.",
        "label": "Trading Symbol",
        "terseLabel": "Trading Symbol"
       }
      }
     },
     "localname": "TradingSymbol",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "tradingSymbolItemType"
    },
    "dei_WrittenCommunications": {
     "auth_ref": [
      "r6"
     ],
     "lang": {
      "en-us": {
       "role": {
        "documentation": "Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.",
        "label": "Written Communications",
        "terseLabel": "Written Communications"
       }
      }
     },
     "localname": "WrittenCommunications",
     "nsuri": "http://xbrl.sec.gov/dei/2020-01-31",
     "presentation": [
      "http://www.catalystbiosciences.com//20211007/taxonomy/role/DocumentDocumentAndEntityInformation"
     ],
     "xbrltype": "booleanItemType"
    }
   },
   "unitCount": 0
  }
 },
 "std_ref": {
  "r0": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b"
  },
  "r1": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "d1-1"
  },
  "r2": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "13e",
   "Subsection": "4c"
  },
  "r3": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "14d",
   "Subsection": "2b"
  },
  "r4": {
   "Name": "Exchange Act",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "14a",
   "Subsection": "12"
  },
  "r5": {
   "Name": "Regulation 12B",
   "Number": "240",
   "Publisher": "SEC",
   "Section": "12",
   "Subsection": "b-2"
  },
  "r6": {
   "Name": "Securities Act",
   "Number": "230",
   "Publisher": "SEC",
   "Section": "425"
  }
 },
 "version": "2.1"
}
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>16
<FILENAME>0001193125-21-297901-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
begin 644 0001193125-21-297901-xbrl.zip
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M<3:BE"9D+ +]Z .V9!38BXGTN7X6D66A[$W$;2OK<(A7];V-PZZ6>'8T-D=
MB,51B$7V;J]8/!@A/X&)T5<O)3.8@TM"S\R2YE*$89>];X]Q.#XA4RO\2W,U
M&"$A,H<[W6_.G,YKXY-K;7SC:,B$5Y74,]-=T64H\;RO\PG.H)EU.;?"&H6[
M)R*KK*G0>DF+8M4JK8$;B[-Q%#9%W$^A;XI/$YI"O<H#!^O-%\2,(*@N5_1Z
MK)<^@"^#&(*<-BY72].A0,:1H[BK0?/^XN=6%I_Z7((X6@--VK:_^N^!UI,?
M'_Q<DP:$P]?)Q5Z+9+E)F.?W1IMRT?(],Z(.>ZO_?ZJ+3YI8+BZHR&S9,(Q
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M0O]EN0&J$EPSK)5-9S8T _ $+UT.@&<[ -ZS&P#/= "\+@; ^W8#,-OPS@8
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ML:L)^V1AS-FFUM':SX7]T.Q&:5\R+2%SS)-VN$PZ)%29L?HF#)];3<]I2E\
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M9WC'.9L4)85E:O?6H[N$^8'R#)0CR(I-7[4X52!K]QC,I4PO$0Z23TMC338
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M[@S"A.'5%\FA?IJMB^YCZ]#ES!,8TMD[E@FT#<[8HQ@*H)A!!)[AGAH"!_2
M1.%.>@P-IDWF; EYWEM4'(#<GY(#$(.4)DV)(E$C5V*2PN(;?P)35**\9;12
MDDA0XS2)R82ZK)D-4 3XY;M0ETMXXO5T#5=]*]%0(%;_N]R$V%.(E(-9@>:L
MLL9D=="PT,#WY:-%?45FPD*#:?*,.<Z%9AH&=Z[(%!9VLB'%& D)S?P$9[>#
MGL@Q4'\(]8K2.F!RP!XR#2H,LFQC#5,-$R.S+:O0+IN\T&1RBT5SCP/'&;K;
MM$I? S'HG5KTUN:B&SGH)A1 $+S:EF>(A&,#QB_#""8O>EON*-*QP?"C2IB!
M_X3KNX/'*L'EE,9"_PH02V*&'!B,!O/-#3H@O9RFD:$0FQ]*9^BJ6D XJ GH
M26Y="[ O2^.OL3>SG7MS/KD>8&0! EC7YQ#A<JPC=,MDOE:%#>(X\XL\2NA%
MM AY*2G+PU_5V_YU_ZR/6;Z??WD&%YX\@4AC__!!M[-_KF<:^#DAN'8M<&T0
M%@^.OG@X/4@H$P'A10GB444X4ZT6&FQ*F!D45LE)A/ @_HFP!62 W3&!3!UA
M&$%1=H&U%A^*JCA8HUIW.U2*\>*]&48!_I/D5$ ?*#:IHTLR]C)/CV<A98E3
MS$K-(0+,$L:&LYD)Q?*1Y#JP1/&MV'/"G!*\ QV9!OM52*( ,T9Y09$C%D?
ML%#.N0:(X!U85E_=P<!NY^_DH/IH!@:4EXW1"59PW\'HF8DYR1/@#(@8O9@
M4V6:LW-&_"0\3ZA.QF?J<QW$33X Z.MV</3<&QH7@)4I6+O%E+ Y+AKAVW8;
M;N,ZS+[Q J1%@UD24;A=%X7UR$-K5K:]VN(=P[0$)-'@1F,\62F:7,=;-'3
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MS._81O2LC"L(,5@"8@IAC($W["#/T[!J%\&R[?ZA> H[/<(MS@%)+TO#\W%
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MT%=&MU=G[>'MANEW?^_?1X1^Y%*_Z0;V0]2B:Y![NYAW\1;7Z_,$CYN]=^/
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=.3DQ+FAT;5!+!08     !@ & '\!   D1      !

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
