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Schedule of Other Accrued Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | ---
Payables And Accruals [Abstract] |  |
Manufacturing | $ 1,381 | $ 2,238
Biogen | 868 |
Pre-clinical | 773 |
Professional and consulting services | 509 | 3,979
Clinical | 361 | 291
Other | 180 | 235
Total other accrued liabilities | $ 4,072 | $ 6,743

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