XML 59 R48.htm IDEA: XBRL DOCUMENT
v3.22.2.2

Restructuring - Additional Information (Detail) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
May 31, 2022 USD ($) | Mar. 31, 2022 Employee | Nov. 30, 2021 | Jun. 30, 2022 USD ($) | Jun. 30, 2022 USD ($) | Dec. 31, 2021 USD ($)
Restructuring Cost And Reserve [Line Items] |  |  |  |  |  |
Percent of employees terminated |  |  | 35.00% |  |  |
Severance costs and expenses |  |  |  |  |  | $ 400
Charges related to write off of prepaid manufacturing cost |  |  |  |  |  | 3,800
Restructuring liability |  |  |  |  |  | $ 200
Number of employees terminated | Employee |  | 22 |  |  |  |
Remaining number of full time employees | Employee |  | 5 |  |  |  |
Gain (loss) on disposal |  |  |  | $ 57,245 | $ 57,245 |
Proceeds from the sale of complement portfolio to Vertex |  |  |  |  | 55,000 |
Dren Bio, Inc. and Copia Scientific, LLC |  |  |  |  |  |
Restructuring Cost And Reserve [Line Items] |  |  |  |  |  |
Total consideration for sales agreements |  |  |  | 400 | 400 |
Gain (loss) on disposal |  |  |  | $ (200) |  |
Vertex Pharmaceuticals Incorporated |  |  |  |  |  |
Restructuring Cost And Reserve [Line Items] |  |  |  |  |  |
Gain (loss) on disposal | $ 57,400 |  |  |  |  |
Proceeds from the sale of complement portfolio to Vertex | 60,000 |  |  |  |  |
Upfront payment received | 55,000 |  |  |  |  |
Post closing indemnification obligation | $ 5,000 |  |  |  |  |
Transaction costs |  |  |  |  | 2,600 |
Operating Expense |  |  |  |  |  |
Restructuring Cost And Reserve [Line Items] |  |  |  |  |  |
Severance and other charges |  |  |  |  | $ 1,000 |

X
- Definition Charges related to write off of prepaid manufacturing costs. + References No definition available. + Details
Name: | cbio_ChargesRelatedToWriteOffOfPrepaidManufacturingCost
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Disposal of assets transaction costs. + References No definition available. + Details
Name: | cbio_DisposalOfAssetsTransactionCosts
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Post closing indemnification obligation. + References No definition available. + Details
Name: | cbio_PostClosingIndemnificationObligation
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Remaining number of full time employees. + References No definition available. + Details
Name: | cbio_RemainingNumberOfFullTimeEmployees
Namespace Prefix: | cbio_
Data Type: | xbrli:integerItemType
Balance Type: | na
Period Type: | duration

X
- Definition Restructuring liability. + References No definition available. + Details
Name: | cbio_RestructuringLiability
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Severance and other costs. + References No definition available. + Details
Name: | cbio_SeveranceAndOtherCosts
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Upfront payment received. + References No definition available. + Details
Name: | cbio_UpfrontPaymentReceived
Namespace Prefix: | cbio_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Amount of consideration received or receivable for the disposal of assets and liabilities, including discontinued operation. + References No definition available. + Details
Name: | us-gaap_DisposalGroupIncludingDiscontinuedOperationConsideration
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Definition Amount of gain (loss) on sale or disposal of assets, including but not limited to property plant and equipment, intangible assets and equity in securities of subsidiaries or equity method investee. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 + Details
Name: | us-gaap_GainLossOnDispositionOfAssets1
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition The cash inflow from disposal of asset without physical form usually arising from contractual or other legal rights, excluding goodwill. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3179-108585 + Details
Name: | us-gaap_ProceedsFromSaleOfIntangibleAssets
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The number of positions eliminated during the period as a result of restructuring activities. + References No definition available. + Details
Name: | us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated
Namespace Prefix: | us-gaap_
Data Type: | xbrli:integerItemType
Balance Type: | na
Period Type: | duration

X
- Definition The number of positions eliminated during the period as a percentage of total positions eliminated during the period in connection with the restructuring plan(s). + References No definition available. + Details
Name: | us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | duration

X
- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
Name: | us-gaap_RestructuringCostAndReserveLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Amount of expenses for special or contractual termination benefits provided to current employees involuntarily terminated under a benefit arrangement associated exit or disposal activities pursuant to an authorized plan. Excludes expenses related to one-time termination benefits, a discontinued operation or an asset retirement obligation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 + Details
Name: | us-gaap_SeveranceCosts1
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Details
Name: | us-gaap_BusinessAcquisitionAxis=cbio_DrenBioIncAndCopiaScientificLLCMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_BusinessAcquisitionAxis=cbio_VertexPharmaceuticalsIncorporatedMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_IncomeStatementLocationAxis=us-gaap_OperatingExpenseMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |