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Stock Based Compensation - Summary of Option Activity Under Company's 2018 Plan (Detail) - $ / shares
 9 Months Ended 12 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Number of Shares Underlying Outstanding Options    
Number of Shares Underlying Outstanding Options, Beginning Balance 2,603,630  
Number of Shares Underlying Outstanding Options, Options granted [1] 10,270,911  
Number of Shares Underlying Outstanding Options, Options forfeited and cancelled [1] (3,920,511)  
Number of Shares Underlying Outstanding Options, Options expired (47,319)  
Number of Shares Underlying Outstanding Options, Ending Balance 8,906,711 2,603,630
Number of Shares Underlying Outstanding Options, Exercisable - September 30, 2022 4,331,100  
Weighted- Average Exercise Price    
Weighted- Average Exercise Price, Beginning Balance $ 7.70  
Weighted- Average Exercise Price, Options granted [1] 1.34  
Weighted- Average Exercise Price, Options forfeited and cancelled [1] 5.16  
Weighted- Average Exercise Price, Options expired 13.27  
Weighted- Average Exercise Price, Ending Balance 1.42 $ 7.70
Weighted- Average Exercise Price, Exercisable - September 30, 2022 $ 2.38  
Weighted-Average Remaining Contractual Term (Years)    
Weighted-Average Remaining Contractual Term (Years), Outstanding Balance 7 years 9 months 10 days 7 years 5 months 15 days
[1] Includes options that were cancelled and re-granted as part of the option modification from the special cash dividend, as further discussed above.