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Restructuring - Additional Information (Detail)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended
Aug. 21, 2023
USD ($)
Jun. 05, 2023
USD ($)
Mar. 08, 2023
USD ($)
Jan. 12, 2023
USD ($)
Jun. 30, 2023
USD ($)
Mar. 31, 2023
USD ($)
Feb. 28, 2023
USD ($)
May 31, 2022
USD ($)
Mar. 31, 2022
Employee
Nov. 30, 2021
Jun. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Restructuring Cost And Reserve [Line Items]                            
Percent of employees terminated                   35.00%        
Number of Employees terminated | Employee                 22          
Remaining number of full time employees | Employee                 5          
Proceeds from Sale of Intangible Assets                         $ 1,000  
Gain (loss) on disposal                         4,736 $ 57,245
Amount of dividend payment       $ 7,600                    
Contingent Value Rights Agreement                            
Restructuring Cost And Reserve [Line Items]                            
Distribution to CVR holders from asset sale proceeds $ 1,500 $ 3,500       $ 200 $ 200              
Amount of dividend payment $ 1,500 $ 3,500 $ 200   $ 3,500                  
Vertex Pharmaceuticals Incorporated                            
Restructuring Cost And Reserve [Line Items]                            
Proceeds from Sale of Intangible Assets               $ 60,000            
Upfront payment received               55,000            
Post closing indemnification obligation               5,000            
Gain (loss) on disposal               $ 57,400            
Transaction costs                     $ 2,600      
GCBP Asset Purchase Agreement                            
Restructuring Cost And Reserve [Line Items]                            
Proceeds from Sale of Intangible Assets             6,000              
Upfront payment received             1,000              
Post closing indemnification obligation             5,000              
Gain (loss) on disposal             $ 4,700              
Transaction costs                         800  
Dren Bio, Inc. and Copia Scientific, LLC                            
Restructuring Cost And Reserve [Line Items]                            
Total consideration for sales agreements                         $ 400  
Gain (loss) on disposal                           $ (200)
Operating Expense                            
Restructuring Cost And Reserve [Line Items]                            
Restructuring costs                       $ 1,000