    <SEC-DOCUMENT>0001140361-25-014874-index.html : 20250422
    <SEC-HEADER>0001140361-25-014874.hdr.sgml : 20250422
    <ACCEPTANCE-DATETIME>20250422134413
    ACCESSION NUMBER:		0001140361-25-014874
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20241231
    FILED AS OF DATE:		20250422
    DATE AS OF CHANGE:		20250422
    EFFECTIVENESS DATE:		20250422

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			GYRE THERAPEUTICS, INC.
    		CENTRAL INDEX KEY:			0001124105
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				562020050
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-51173
    		FILM NUMBER:		25856818

    	BUSINESS ADDRESS:
    		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130
    		BUSINESS PHONE:		(619) 949-3681

    	MAIL ADDRESS:
    		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	CATALYST BIOSCIENCES, INC.
    		DATE OF NAME CHANGE:	20150820

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	TARGACEPT INC
    		DATE OF NAME CHANGE:	20000919
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ny20044429x3_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: ny20044429x3_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>