<SEC-DOCUMENT>0001140361-25-000425.txt : 20250107
<SEC-HEADER>0001140361-25-000425.hdr.sgml : 20250107
<ACCEPTANCE-DATETIME>20250107160128
ACCESSION NUMBER:		0001140361-25-000425
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250105
FILED AS OF DATE:		20250107
DATE AS OF CHANGE:		20250107

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Zhang Ping
		CENTRAL INDEX KEY:			0002050176
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51173
		FILM NUMBER:		25514819

	MAIL ADDRESS:	
		STREET 1:		12770 HIGH BLUFF DRIVE
		STREET 2:		SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GYRE THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001124105
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				562020050
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		(619) 949-3681

	MAIL ADDRESS:	
		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CATALYST BIOSCIENCES, INC.
		DATE OF NAME CHANGE:	20150820

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGACEPT INC
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>FORM 3
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    <periodOfReport>2025-01-05</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001124105</issuerCik>
        <issuerName>GYRE THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>GYRE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002050176</rptOwnerCik>
            <rptOwnerName>Zhang Ping</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GYRE THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>12770 HIGH BLUFF DRIVE, SUITE 150</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92130</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
        </reportingOwnerRelationship>
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    <remarks>Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Ruoyu Chen, as attorney-in-fact for Ping Zhang</signatureName>
        <signatureDate>2025-01-07</signatureDate>
    </ownerSignature>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ef20041166_ex24.htm
<DESCRIPTION>EXHIBIT 24
<TEXT>
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  <div style="text-align: right;"> <font style="font-weight: bold;">Exhibit 24</font><br>
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  <div>
    <div><br>
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    <div style="text-align: center; font-weight: bold;">POWER OF ATTORNEY</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">Know all by these presents that the undersigned hereby constitutes and appoints each of Han Ying, Ruoyu Chen, Yang Zheng, Branden Berns, and Ryan Murr, and any of their substitutes, signing singly,
      as the undersigned&#8217;s true and lawful attorney-in-fact to:</div>
    <div>&#160;</div>
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          <td style="width: 18pt; vertical-align: top;">1.</td>
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            <div>prepare, execute in the undersigned&#8217;s name and on the undersigned&#8217;s behalf, and submit to the U.S. Securities and Exchange Commission (the &#8220;SEC&#8221;) a Form ID, including amendments thereto, and any other document necessary or appropriate to
              obtain codes, passwords, and passphrases enabling the undersigned to make electronic filings with the SEC of reports require by the Securities Exchange Act of 1934 or any rule or regulation of the SEC;</div>
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    <div>&#160;</div>
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          <td style="width: 18pt; vertical-align: top;">2.</td>
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            <div>execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as a director, officer and/or ten percent stockholder of Gyre Therapeutics, Inc. (the &#8220;Company&#8221;), Forms 3, 4, and 5 in accordance with Section 16(a) of the
              Securities Exchange Act of 1934 and the rules thereunder;</div>
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    </table>
    <div>&#160;</div>
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          <td style="width: 18pt; vertical-align: top;">3.</td>
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            <div>do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, complete and execute any amendment or amendments thereto, and timely file such form
              with the SEC and any securities exchange or similar authority; and</div>
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    <div>&#160;</div>
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          <td style="width: 18pt; vertical-align: top;">4.</td>
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            <div>take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that
              the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact&#8217;s
              discretion.</div>
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    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the
      exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that each
      such attorney-in-fact, or such attorney-in-fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted.&#160; The undersigned also ratifies hereby any action
      previously taken by each attorney-in-fact that would have been authorized by this power of attorney if it has been in effect at the time such action was taken.&#160; The undersigned acknowledges that each attorney-in-fact, in serving in such capacity at
      the request of the undersigned, is not assuming, nor is the Company assuming, any of the undersigned&#8217;s responsibilities to comply with Section 16 of the Securities Exchange Act of 1934, as amended.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned&#8217;s holdings of and transactions in
      securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to each of the foregoing attorneys-in-fact.</div>
    <div>&#160;</div>
    <div style="text-align: justify;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of January 5, 2025.</div>
    <div>&#160;</div>
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              <div>By:</div>
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            <td style="width: 23%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">/s/ Ping Zhang</td>
            <td style="width: 23.5%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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              <div>Name: Ping Zhang</div>
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