<SEC-DOCUMENT>0001140361-25-032710.txt : 20250826
<SEC-HEADER>0001140361-25-032710.hdr.sgml : 20250826
<ACCEPTANCE-DATETIME>20250826160335
ACCESSION NUMBER:		0001140361-25-032710
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250818
FILED AS OF DATE:		20250826
DATE AS OF CHANGE:		20250826

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Weng Dan
		CENTRAL INDEX KEY:			0002083482
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51173
		FILM NUMBER:		251257554

	MAIL ADDRESS:	
		STREET 1:		12730 HIGH BLUFF DRIVE
		STREET 2:		SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GYRE THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001124105
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				562020050
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		12770 HIGH BLUFF DRIVE
		STREET 2:		SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130
		BUSINESS PHONE:		(858) 567-7770

	MAIL ADDRESS:	
		STREET 1:		12770 HIGH BLUFF DRIVE
		STREET 2:		SUITE 150
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92130

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CATALYST BIOSCIENCES, INC.
		DATE OF NAME CHANGE:	20150820

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TARGACEPT INC
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>FORM 3
<TEXT>
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    <periodOfReport>2025-08-18</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001124105</issuerCik>
        <issuerName>GYRE THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>GYRE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002083482</rptOwnerCik>
            <rptOwnerName>Weng Dan</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GYRE THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>12770 HIGH BLUFF DRIVE, SUITE 150</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92130</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Ruoyu Chen, as attorney-in-fact for Dan Weng</signatureName>
        <signatureDate>2025-08-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ef20054599_ex24.htm
<DESCRIPTION>EXHIBIT 24
<TEXT>
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  <div style="text-align: right; font-size: 10pt; font-weight: bold;">Exhibit 24</div>
  <div style="font-size: 10pt;"><br>
  </div>
  <div style="text-align: center; font-size: 10pt; font-weight: bold;">POWER OF ATTORNEY</div>
  <div style="text-align: center; font-size: 10pt; font-weight: bold;"> <br>
  </div>
  <div style="text-indent: 36pt; font-size: 10pt;">Know all by these presents that the undersigned hereby constitutes and appoints each of Ping Zhang, Ruoyu Chen, Yang Zheng, Branden Berns, and Ryan Murr, and any of their substitutes, signing singly, as
    the undersigned&#8217;s true and lawful attorney-in-fact to:</div>
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            <div style="text-align: left;"><font style="font-size: 10pt;">1.</font></div>
          </td>
          <td style="text-align: left; vertical-align: top; width: auto;">
            <div><font style="font-size: 10pt;">prepare, execute in the undersigned&#8217;s name and on the undersigned&#8217;s behalf, and submit to the U.S. Securities and Exchange Commission (the &#8220;SEC&#8221;) a Form ID, including amendments thereto, and any other
                document necessary or appropriate to obtain codes, passwords, and passphrases enabling the undersigned to make electronic filings with the SEC of reports require by the Securities Exchange Act of 1934 or any rule or regulation of the SEC;</font></div>
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    </font></div>
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    <table cellspacing="0" cellpadding="0" class="DSPFListTable" id="zb3a0126a1f02436daa07aa95ad0cab52" style="font-family: 'Times New Roman'; font-size: 9pt; width: 100%;">

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            <div style="text-align: left;"><font style="font-size: 10pt;">2.</font></div>
          </td>
          <td style="text-align: left; vertical-align: top; width: auto;">
            <div><font style="font-size: 10pt;">execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as a director, officer and/or ten percent stockholder of Gyre Therapeutics, Inc. (the &#8220;Company&#8221;), Forms 3, 4, and 5 in accordance
                with Section 16(a) of the Securities Exchange Act of 1934 and the rules thereunder;</font></div>
          </td>
        </tr>

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  </div>
  <div><font style="font-size: 10pt;"> <br>
    </font></div>
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    <table cellspacing="0" cellpadding="0" class="DSPFListTable" id="z50c7cfdac6a9401680e97e4d1c801232" style="font-family: 'Times New Roman'; font-size: 9pt; width: 100%;">

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            <div style="text-align: left;"><font style="font-size: 10pt;">3.</font></div>
          </td>
          <td style="text-align: left; vertical-align: top; width: auto;">
            <div><font style="font-size: 10pt;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, complete and execute any amendment or amendments
                thereto, and timely file such form with the SEC and any securities exchange or similar authority; and</font></div>
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    </font></div>
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            <div style="text-align: left;"><font style="font-size: 10pt;">4.</font></div>
          </td>
          <td style="text-align: left; vertical-align: top; width: auto;">
            <div><font style="font-size: 10pt;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the
                undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact
                may approve in such attorney-in-fact&#8217;s discretion.</font></div>
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  <div style="text-indent: 36pt; font-size: 10pt;"> <br>
  </div>
  <div style="text-indent: 36pt; font-size: 10pt;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of
    any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that each such
    attorney-in-fact, or such attorney-in-fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted.&#160; The undersigned also ratifies hereby any action previously
    taken by each attorney-in-fact that would have been authorized by this power of attorney if it has been in effect at the time such action was taken.&#160; The undersigned acknowledges that each attorney-in-fact, in serving in such capacity at the request of
    the undersigned, is not assuming, nor is the Company assuming, any of the undersigned&#8217;s responsibilities to comply with Section 16 of the Securities Exchange Act of 1934, as amended.</div>
  <div style="text-indent: 36pt; font-size: 10pt;"> <br>
  </div>
  <div style="text-indent: 36pt; font-size: 10pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned&#8217;s holdings of and transactions in
    securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to each of the foregoing attorneys-in-fact.</div>
  <div style="font-size: 10pt;"> <br>
  </div>
  <div style="font-size: 10pt;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of August 18, 2025.</div>
  <div style="font-size: 10pt;"><br>
  </div>
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        <td style="width: 60%; vertical-align: top; font-size: 10pt; padding-bottom: 2px;">&#160;</td>
        <td style="width: 3%; vertical-align: top; font-size: 10pt; padding-bottom: 2px;">
          <div>By:</div>
        </td>
        <td style="width: 37%; vertical-align: top; font-size: 10pt; border-bottom: 2px solid rgb(0, 0, 0);">
          <div>/s/ Dan Weng</div>
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        <td style="width: 60%; vertical-align: top; font-size: 10pt;">&#160;</td>
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          <div>Name: Dan Weng</div>
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