    <SEC-DOCUMENT>0001140361-25-014780-index.html : 20250421
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    <ACCEPTANCE-DATETIME>20250421172354
    ACCESSION NUMBER:		0001140361-25-014780
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		3
    FILED AS OF DATE:		20250421
    DATE AS OF CHANGE:		20250421

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			GYRE THERAPEUTICS, INC.
    		CENTRAL INDEX KEY:			0001124105
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				562020050
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-51173
    		FILM NUMBER:		25854461

    	BUSINESS ADDRESS:
    		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130
    		BUSINESS PHONE:		(619) 949-3681

    	MAIL ADDRESS:
    		STREET 1:		12770 HIGH BLUFF DRIVE, SUITE 150
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92130

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	CATALYST BIOSCIENCES, INC.
    		DATE OF NAME CHANGE:	20150820

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	TARGACEPT INC
    		DATE OF NAME CHANGE:	20000919
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>ny20044429x2_defa14a.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
    Document 1 - file: ny20044429x2_defa14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>ny20044429x2_nc01.jpg
    <TEXT>
    Document 2 - file: ny20044429x2_nc01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>ny20044429x2_nc02.jpg
    <TEXT>
    Document 3 - file: ny20044429x2_nc02.jpg

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    </SEC-DOCUMENT>