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Reconciliation of Consideration Transferred to Total Cash Paid to Acquire Business (Detail) (Crescendo Biosciences, Inc., USD $)
In Thousands, unless otherwise specified
 0 Months Ended
Feb. 28, 2014
Crescendo Biosciences, Inc.
  
Schedule of Business Acquisitions, Cost of Acquired Entity [Line Items]  
Total consideration transferred $ 258,950
Share-based compensation to Crescendo employees 6,929
Change of control payments to Crescendo employees 5,695
Offset: Non-cash fair value purchase option (8,000)
Total cash paid $ 263,574