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Acquisition - Additional Information (Detail) (Crescendo Biosciences, Inc., USD $)
 0 Months Ended
Feb. 28, 2014
Business Acquisition [Line Items]  
Total consideration transferred $ 258,950,000
Business acquisition, cash transferred 225,100,000
Elimination of intercompany balances related to accrued interest and term loan 25,900,000
Fair value of purchase option granted 8,000,000
Business acquisition, amount deposited into escrow account 20,000,000
Share-based compensation to Crescendo employees 6,929,000
Control bonuses paid to Crescendo employees $ 5,695,000
Minimum
  
Business Acquisition [Line Items]  
Period of audit completion 12 months
Maximum
  
Business Acquisition [Line Items]  
Period of audit completion 15 months