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Income Taxes - Schedule of Differences Between Statutory Federal Income Tax Rate and Income Taxes Reported in Consolidated Statements of Operations (Detail)	6 Months Ended		12 Months Ended
	Jun. 30, 2018	Dec. 31, 2017	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2016
Income Tax Disclosure [Abstract]
Federal income tax expense at the statutory rate	21.00%	35.00%	28.10%	35.00%	35.00%
State income taxes, net of federal benefit			2.50%	1.70%	2.20%
Research and development credits, net of the federal tax on state credits			(1.80%)	(7.60%)	(1.40%)
Uncertain tax positions, net of federal benefit			2.00%	3.00%	0.60%
Uncertain tax benefits statute expired, net of federal benefit					(4.80%)
Incentive stock option and employee stock purchase plan expense			(1.10%)	2.00%	(0.30%)
Foreign rate differential			(0.80%)	(1.30%)
Change in valuation allowance			0.50%	7.40%	1.40%
Tax Cut and Jobs Act Impact			(27.30%)
Fair value adjustments related to acquisition contingent consideration			(14.70%)
Early adoption of ASU 2016-09			(0.30%)	7.70%	(8.30%)
Acquisition related transaction costs				1.90%
Other, net			0.90%	0.60%	0.50%
Effective income tax rate			(12.00%)	50.40%	24.90%

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Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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