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v3.25.1

Summary of Significant Accounting Policies and Recent Accounting Pronouncements - Net Loss for the Segment (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2025 | Mar. 31, 2024 | Dec. 31, 2024
Summary of Significant Accounting Policies and Recent Accounting Pronouncements |  |  |
Service revenue - related party | $ 1,926 | $ 697 | $ 697
Cost of service revenue - related party | 1,378 |  |
General and administrative | 6,348 |  | 8,864
Botaretigene Sparoparvovec |  |  | 3,957
AAV-hAQP1 | 4,852 |  | 1,663
AAV-CNGB3 / AAV-CNGA3 |  |  | (1,179)
AAV-GAD | 1,459 |  | 2,170
Other ocular diseases | 1,445 |  | 293
Manufacturing | 17,359 |  | 18,360
Gene Regulation | 2,286 |  | 2,499
Neurodegenerative diseases | 426 |  | 391
Preclinical ocular diseases | 625 |  | 327
Other research and development (1) | (624) |  | 541
Johnson & Johnson Innovative Medicine reimbursement |  |  | (652)
Share-based compensation | 4,887 | 6,960 | 6,960
Depreciation and amortization | 3,081 | 3,275 | 3,275
Total operating expenses | 43,522 | 47,469 | 47,469
Other segment items (2) | 1,615 |  | 26,330
Segment net loss | (39,981) |  | (20,442)
Net Income (Loss) | $ (39,981) | $ (20,442) | $ (20,442)

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