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v3.25.1

Share-Based Compensation (Tables) | 3 Months Ended
--- | ---
Mar. 31, 2025
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
Schedule of Share Option Activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Weighted- | ​
​ | ​ |  | ​ |  | Weighted- |  | ​ | Average | ​
​ | ​ | ​ | ​ | ​ | Average | ​ | ​ | Remaining | ​
​ | ​ | ​ | Number of | ​ | Exercise | ​ | ​ | Contractual | ​
​ | ​ | ​ | Options | ​ | Price | ​ | ​ | Term (years) | ​
Outstanding at December 31, 2024 | ​ |  | 8,232,587 | ​ | $ | 12.57 |  | ​ | 5.35 | years
Granted | ​ |  | — | ​ | $ | — |  | ​ | ​ | ​
Exercised | ​ |  | (638) | ​ | $ | 5.73 |  | ​ | ​ | ​
Forfeited | ​ |  | (208,960) | ​ | $ | 16.39 |  | ​ | ​ | ​
Outstanding at March 31, 2025 | ​ |  | 8,022,989 | ​ | $ | 12.48 | ​ | ​ | 5.18 | years
Options exercisable at March 31, 2025 | ​ |  | 6,956,612 | ​ | $ | 12.85 | ​ |  | 4.79 | years
Options vested and expected to vest at March 31, 2025 | ​ | ​ | 8,022,989 | ​ | $ | 12.48 | ​ | ​ | 5.18 | years
Aggregate intrinsic value of options outstanding as of March 31, 2025 | ​ | $ | 2,228 | ​ |  |  | ​ |  |  | ​
Aggregate intrinsic value of options exercisable as of March 31, 2025 | ​ | $ | 2,079 | ​ |  |  | ​ |  |  | ​
Schedule of Inputs Used in Determining Fair Value of Share Options | ​
​ | ​ | ​ | ​ | ​
​ |  | 2025 |  | 2024
Risk-free interest rate |  | - |  | 4.04 - 4.17%
Expected volatility |  | - |  | 67%
Expected dividend yield |  | - |  | 0%
Expected term (in years) |  | - |  | 3.6 - 6.1
Schedule of Restricted Share Unit (RSU) Activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ |  | ​ |  | Weighted-
​ | ​ | Number of | ​ | Average
​ | ​ | Restricted | ​ | Grant Date
​ | ​ | Share Units | ​ | Fair Value
Outstanding at December 31, 2024 | ​ |  | 4,252,250 | ​ | $ | 8.91
Granted | ​ |  | — | ​ | $ | —
Vested | ​ | ​ | (862,500) | ​ | $ | 13.70
Forfeited | ​ | ​ | — | ​ | $ | —
Outstanding at March 31, 2025 | ​ |  | 3,389,750 | ​ | $ | 7.69
Schedule of Share-Based Compensation Expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three-Month Periods Ended March 31,
​ |  | 2025 |  | 2024
Research and development | ​ | $ | 2,046 | ​ | $ | 2,875
General and administrative | ​ |  | 2,841 | ​ | ​ | 4,085
Total share-based compensation | ​ | $ | 4,887 | ​ | $ | 6,960
Employee Stock Option |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
Schedule of Share-Based Compensation Expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three-Month Periods Ended March 31,
​ |  | 2025 |  | 2024
Research and development | ​ | $ | 939 | ​ | $ | 1,635
General and administrative | ​ | ​ | 597 | ​ | ​ | 1,053
Total share-based compensation | ​ | $ | 1,536 | ​ | $ | 2,688
Restricted Share Units |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
Schedule of Share-Based Compensation Expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three-Month Periods Ended March 31,
​ |  | 2025 |  | 2024
Research and development | ​ | $ | 1,107 | ​ | $ | 1,240
General and administrative | ​ | ​ | 2,244 | ​ | ​ | 3,032
Total share-based compensation | ​ | $ | 3,351 | ​ | $ | 4,272

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- Definition Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Line items represent financial concepts included in a table. 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