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Note 9 - Stock-based Compensation (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

		Year Ended December 31,
		2024				2023
		(000's)
Research and development		$	2,971			$	1,998
General and administrative			5,589				4,122
Total		$	8,560			$	6,120

Nonvested Restricted Stock Shares Activity [Table Text Block]

		Number of Nonvested Options (000's)				Weighted Average Exercise Price Per Share				Weighted Average Remaining Contractual Life (in years)				Aggregate Intrinsic Value (000's)
Outstanding at December 31, 2022			5,378			$	3.89				8.24			$	6,316
Granted			2,803			$	3.69				9.18			$	—
Exercised			(29	)		$	1.75				—			$	35
Forfeited/cancelled			(276	)		$	4.29				—			$	164
Outstanding at December 31, 2023			7,876			$	3.81				8.05			$	11
Granted			6,193			$	1.58				7.10			$	—
Exercised			—			$	—				—			$	—
Forfeited/cancelled			(7	)		$	3.04				—			$	—
Outstanding at December 31, 2024			14,062			$	2.83				6.23			$	579
Vested at December 31, 2024			6,551			$	3.67				5.28			$	49

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Year Ended December 31,
		2024				2023
Expected term (in years)			6.0				6.0
Risk-free rate			3.92	%			3.83	%
Expected volatility			81	%			87	%

Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]

		Shares (000's)				Weighted Average Price Per Share				Weighted Average Fair Value (000's)
Unvested, December 31, 2022			900			$	3.83			$	3,447
Granted			900				3.93				3,537
Vested			(300	)			3.83				(1,149	)
Forfeited or canceled			—				—				—
Unvested, December 31, 2023			1,500			$	3.83			$	5,745
Granted			2,791			$	1.89			$	5,275
Vested			(525	)			3.87				(2,032	)
Forfeited or canceled			—				—				—
Unvested, December 31, 2024			3,766			$	2.41			$	9,076

X

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Tabular disclosure of the changes in outstanding nonvested restricted stock shares.

+ References

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-Section 50
-Subparagraph (c)
-Paragraph 2
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-Topic 718
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