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Note 13 - Income Taxe (Tables)

12 Months Ended

Dec. 31, 2024

Notes Tables

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

		December 31,
		2024				2023
Statutory rate			21.0	%			21.0	%
State taxes			7.0	%			7.9	%
Share-based compensation & other nondeductible expenses			-1.1	%			1.5	%
Research credits			5.8	%			7.3	%
Other			-0.7	%			-0.6	%
Change in valuation allowance			-32.0	%			-37.1	%
Total			0.0	%			0.0	%

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		December 31,
		2024				2023
Deferred tax assets		(000's)
Federal net operating loss carryforwards		$	16,775			$	13,760
State net operating loss carryforwards			5,063				3,719
Research and development credits			9,252				6,387
Section 174 Capitalization			22,724				15,525
Share-based compensation			3,922				2,701
Lease liabilities			1,812				474
Capitalized licensing fees			1,375				1,484
Other			494				234
Subtotal			61,417				44,284
Less valuation allowance			(59,521	)			(43,799	)
Deferred tax assets, net of valuation allowance			1,896				485
Deferred tax liabilities
Right-of-use assets			(1,839	)			(485	)
Other			(57	)			—
Net deferred tax assets		$	—			$	—

X

- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

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-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Publisher FASB
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- Definition

Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 55
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-Publisher FASB
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