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Note 13 - Income Taxe (Details Textual) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Expense (Benefit) $ 0 $ 0
Deferred Tax Assets, Valuation Allowance 59,521 43,799
Deferred Tax Assets, Capitalized Research and Development Expenses 39,900  
Deferred Tax Assets, Amortized Research and Development Expenses 14,300  
Unrecognized Tax Benefits 0 0
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total 0 $ 0
Domestic Tax Jurisdiction [Member]    
Operating Loss Carryforwards 79,800  
Domestic Tax Jurisdiction [Member] | Research Tax Credit Carryforward [Member]    
Tax Credit Carryforward, Amount 7,300  
State and Local Jurisdiction [Member]    
Operating Loss Carryforwards 80,000  
State and Local Jurisdiction [Member] | Research Tax Credit Carryforward [Member]    
Tax Credit Carryforward, Amount $ 2,400