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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:    
Net loss $ (49,375) $ (42,494)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 589 699
Share-based compensation 8,560 6,120
Amortization of premium and discount on marketable securities (1,651) (3,226)
ROU asset amortization 1,164 1,191
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (4,857) 6,762
Accounts payable (1,841) 708
Accrued expenses 3,773 (9,176)
Operating lease liability (1,217) (1,202)
Net cash used in operating activities (44,855) (40,618)
Cash flows from investing activities:    
Purchases of marketable securities (88,158) (155,418)
Proceeds from sale or maturities of marketable securities 134,974 182,413
Purchases of property and equipment (44) (30)
Net cash provided by (used) in investing activities 46,772 26,965
Cash flows from financing activities:    
Proceeds from issuance of common stock 18,113 3,126
Issuance costs from issuance of common stock (543) (94)
Proceeds from exercise of stock options 0 62
Taxes related to the vesting of RSUs 232 159
Net cash provided by financing activities 17,338 2,935
Net change in cash and cash equivalents 19,255 (10,718)
Cash and cash equivalents at beginning of year 24,228 34,946
Cash and cash equivalents at end of year 43,483 24,228
Supplemental disclosure of cash flow information    
Unrealized (gain) loss on marketable securities $ (173) $ (339)