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v3.22.1

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Cash flows from operating activities: |  |
Net loss | $ (23,030) | $ (15,339)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization expense | 84 | 9
Non-cash lease expense | 323 |
Premium amortization and discount accretion on marketable securities, net | 6 | 64
Stock-based compensation expense, including employee stock purchase plan expense | 4,965 | 3,208
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 172 | 291
Other assets | (240) |
Accounts payable | 245 | (327)
Other current liabilities | (113) | 1,010
Operating lease liabilities | (315) |
Net cash used in operating activities | (17,903) | (11,084)
Cash flows from investing activities: |  |
Purchase of equipment | (30) | (420)
Maturities of marketable securities | 148,750 | 1,000
Purchases of marketable securities | (123,153) | (280,164)
Net cash provided by (used in) investing activities | 25,567 | (279,584)
Cash flows from financing activities: |  |
Proceeds from exercise of stock options | 33 |
Net cash provided by financing activities | 33 |
Net increase (decrease) in cash and cash equivalents | 7,697 | (290,668)
Cash and cash equivalents at beginning of period | 13,812 | 338,549
Cash and cash equivalents at end of period | 21,509 | 47,881
Supplemental disclosure of non-cash investing and financing activities: |  |
Reclassification of prepaid expenses and other current liabilities into other assets | 2,014 |
Vesting of early exercised stock options | $ 31 | 31
Purchases of property and equipment included in accounts payable |  | $ 39

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