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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2022
Stock-Based Compensation |
Schedule of fair value assumptions | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | March 31, | ​ | March 31,
​ | ​ | 2022 | ​ | 2021
Risk-free interest rate |  | ​ | 1.69% |  | ​ | 0.43%
Expected term (in years) | ​ | ​ | 6.06 | ​ | ​ | 5.93
Expected volatility | ​ | ​ | 79.17% | ​ | ​ | 77.34%
Expected dividend yield |  |  | — | ​ | ​ | —
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Weighted | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Average | ​ | ​ | ​
​ | ​ | ​ | ​ | Average | ​ | Remaining | ​ | ​ | ​
​ | ​ | Number of | ​ | Exercise | ​ | Contractual | ​ | Aggregate
​ | ​ | Shares | ​ | Price | ​ | Term | ​ | Intrinsic Value
​ | ​ | ​ | ​ | ​ | ​ | (in years) | ​ | (in thousands)
Outstanding as of December 31, 2021 |  | 5,768,028 |  | $ | 15.99 |  | 8.82 |  | $ | 11,365
Granted | ​ | 2,663,650 | ​ | ​ | 7.07 | ​ | ​ | ​ | ​ | —
Exercised(1) | ​ | (22,744) | ​ | ​ | 4.02 | ​ | — | ​ | ​ | —
Forfeited | ​ | (40,581) | ​ | ​ | 22.39 | ​ | — | ​ | ​ | —
Outstanding as of March 31, 2022(2) | ​ | 8,368,353 | ​ | $ | 13.16 | ​ | 8.76 | ​ | $ | 1,031
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Options vested and exercisable as of March 31, 2022 | ​ | 2,138,539 | ​ | $ | 13.44 | ​ | 8.29 | ​ | $ | 710
Options expected to vest as of March 31, 2022 | ​ | 6,229,814 | ​ | $ | 13.06 | ​ | 8.92 | ​ | $ | 321
​
(1) | Exercised amount includes vesting of early exercised options.
(2) | Balance as of March 31, 2022 includes 39,609 unvested early exercised stock options.
Summary of restricted stock activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Number of Shares | ​ | Grant Date Fair Value
Unvested restricted stock as of December 31, 2021 |  | ​ | 493,185 |  | $ | 2.40
Granted | ​ | ​ | — | ​ | ​ | —
Vested | ​ | ​ | (49,318) | ​ | ​ | 2.40
Forfeited | ​ | ​ | — | ​ | ​ | —
Unvested restricted stock as of March 31, 2022 |  | ​ | 443,867 | ​ | $ | 2.40
Schedule of stock-based compensation expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended March 31,
​ | ​ | 2022 | ​ | 2021
Research and development |  | $ | 3,067 |  | $ | 1,734
General and administrative |  |  | 1,898 | ​ | ​ | 1,474
Total |  | $ | 4,965 | ​ | $ | 3,208

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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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