<SEC-DOCUMENT>0000929638-23-000560.txt : 20230214
<SEC-HEADER>0000929638-23-000560.hdr.sgml : 20230214
<ACCEPTANCE-DATETIME>20230214150801
ACCESSION NUMBER:		0000929638-23-000560
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230214
DATE AS OF CHANGE:		20230214
GROUP MEMBERS:		BIHUA CHEN
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE FUND II, LP
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE FUND III, LP
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE GP II, LLC
GROUP MEMBERS:		CORMORANT PRIVATE HEALTHCARE GP III, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Olema Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001750284
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				300409740
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91849
		FILM NUMBER:		23627723

	BUSINESS ADDRESS:	
		STREET 1:		512 2ND STREET, 4TH FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94107
		BUSINESS PHONE:		(415) 651-3316

	MAIL ADDRESS:	
		STREET 1:		512 2ND STREET, 4TH FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94107

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cormorant Asset Management, LP
		CENTRAL INDEX KEY:			0001583977
		IRS NUMBER:				462108927
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		857-702-0388

	MAIL ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cormorant Asset Management, LLC
		DATE OF NAME CHANGE:	20130807
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>schedule13g.htm
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">UNITED STATES</div>
            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</div>
            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Washington, D.C. 20549</div>
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            <div style="text-align: center; font-size: 14pt; font-weight: bold;">SCHEDULE 13G</div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Under the Securities Exchange Act of 1934</div>
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            <div style="text-align: center; font-family: 'Times New Roman';"><font style="font-weight: bold;">(Amendment No. 3)</font>*</div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Olema Pharmaceuticals, Inc.</div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">Common Stock</div>
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            <div style="text-align: center; font-family: 'Times New Roman';">(CUSIP Number)</div>
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            <div style="text-align: center; font-family: 'Times New Roman'; font-weight: bold;">December 31, 2022</div>
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            <div style="text-align: center; font-family: 'Times New Roman';">(Date of Event which Requires Filing of this Statement)</div>
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    <div style="margin-right: 9.35pt; font-family: 'Times New Roman';">Check the appropriate box to designate the rule pursuant to which this Schedule is filed:</div>
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            <div style="font-family: 'Times New Roman';">Rule 13d-1(d)</div>
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    <div>&#160;</div>
    <div><br>
    </div>
    <div>&#160;</div>
    <div><br>
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    <div>&#160;</div>
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    <div>&#160;</div>
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    <div>&#160;</div>
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    <div style="font-family: 'Times New Roman';">___________________________________</div>
    <div style="text-indent: 36pt; font-family: 'Times New Roman';">*&#160; The remainder of this cover page shall be filled out for a reporting person&#8217;s initial filing on this form with respect to the subject class of securities, and for any subsequent
      amendment containing information which would alter the disclosures provided in a prior cover page.</div>
    <div>&#160;</div>
    <div style="text-indent: 45pt; font-family: 'Times New Roman';">The information required in the remainder of this cover page shall not be deemed to be &#8220;filed&#8221; for the purpose of Section&#160;18 of the Securities Exchange Act of 1934 (&#8220;Act&#8221;) or otherwise
      subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, <font style="font-style: italic;">see</font> the Notes).</div>
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              <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
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              <div style="font-family: 'Times New Roman';">68062P106</div>
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              <div style="font-family: 'Times New Roman';">1</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
              <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
            </td>
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            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">2</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
            </td>
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            <td style="width: 6.79%; vertical-align: top;">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top;">
              <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
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            <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
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              <div style="font-family: 'Times New Roman';">3</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">SEC Use Only</div>
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            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">4</div>
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              <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Delaware</div>
            </td>
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          <tr>
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              <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
              <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
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            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
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          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">1,582,000 shares</div>
              <div>&#160;</div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">1,582,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">9</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">1,582,000 shares<br>
                <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">10</div>
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              <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
              <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
            </td>
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          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">11</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">3.91%</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">12</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">PN (Partnership)</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <div> <br>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
      </div>
      <div>
        <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 15%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
              </td>
              <td style="width: 85%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">68062P106</div>
              </td>
            </tr>

        </table>
      </div>
      <div> <br>
      </div>
      <div>
        <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z2fa07e23f36946b9942b71c0eb4afe2d" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">1</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
                <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC</div>
                <div>&#160;</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">2</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top;">&#160;</td>
              <td colspan="2" style="width: 93.01%; vertical-align: top;">
                <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">3</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">SEC Use Only</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">4</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">Delaware</div>
              </td>
            </tr>
            <tr>
              <td colspan="2" rowspan="4" style="width: 17.76%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
                <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
              </td>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">0 shares</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">1,582,000 shares</div>
                <div><font style="font-family: 'Times New Roman';"> </font>&#160;</div>
                <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">0 shares</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">1,582,000 shares</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">9</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">1,582,000 shares</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">10</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
                <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">11</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">3.91%</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">12</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">OO (Limited Liability Company)</div>
              </td>
            </tr>

        </table>
      </div>
      <div> <br>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
      </div>
      <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 15%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
            </td>
            <td style="width: 85%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">68062P106</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div>
      <div>
        <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z0e8b19c17c734830a735e1f14fb156c1" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">1</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
                <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund III, LP</div>
                <div>&#160;</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">2</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top;">&#160;</td>
              <td colspan="2" style="width: 93.01%; vertical-align: top;">
                <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">3</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">SEC Use Only</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">4</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">Delaware</div>
              </td>
            </tr>
            <tr>
              <td colspan="2" rowspan="4" style="width: 17.76%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
                <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
                <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
              </td>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">0 shares</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">500,000 shares</div>
                <div><font style="font-family: 'Times New Roman';"> </font>&#160;</div>
                <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">0 shares</div>
              </td>
            </tr>
            <tr>
              <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">500,000 shares</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">9</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">500,000 shares</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">10</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
                <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">11</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">1.24%</div>
                <div style="font-family: 'Times New Roman';"> <br>
                </div>
                <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
              </td>
            </tr>
            <tr>
              <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">12</div>
              </td>
              <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
                <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
                <div>&#160;</div>
                <div style="font-family: 'Times New Roman';">PN (Partnership)</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
      </div>
      <div>
        <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 15%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
              </td>
              <td style="width: 85%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">68062P106</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zd9fedb483b6743c69dfbb38336590739" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">1</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
              <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP III, LLC</div>
              <div>&#160;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">2</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top;">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top;">
              <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">3</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">SEC Use Only</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">4</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Delaware</div>
            </td>
          </tr>
          <tr>
            <td colspan="2" rowspan="4" style="width: 17.76%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
              <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
            </td>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">500,000 shares</div>
              <div><font style="font-family: 'Times New Roman';"> </font>&#160;</div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">500,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">9</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">500,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">10</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
              <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">11</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">1.24%</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">12</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">OO (Limited Liability Company)</div>
            </td>
          </tr>

      </table>
      <div>
        <div> <br>
        </div>
        <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
          <div style="page-break-after: always;" class="BRPFPageBreak">
            <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
        </div>
        <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 15%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
              </td>
              <td style="width: 85%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">68062P106</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z6834de5193954709ba347598bb511a7c" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">1</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
              <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP</div>
              <div>&#160;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">2</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top;">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top;">
              <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">3</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">SEC Use Only</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">4</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Delaware</div>
            </td>
          </tr>
          <tr>
            <td colspan="2" rowspan="4" style="width: 17.76%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
              <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
            </td>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">9</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares<br>
                <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">10</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
              <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">11</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">5.15%</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">12</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">PN (Partnership)</div>
            </td>
          </tr>

      </table>
      <div>
        <div> <br>
        </div>
        <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
          <div style="page-break-after: always;" class="BRPFPageBreak">
            <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
        </div>
        <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

            <tr>
              <td style="width: 15%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
              </td>
              <td style="width: 85%; vertical-align: top;">
                <div style="font-family: 'Times New Roman';">68062P106</div>
              </td>
            </tr>

        </table>
      </div>
      <div><br>
      </div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z13e0bf66547342ee8f552e1d26ac38d7" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">1</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Names of Reporting Persons.</div>
              <div style="font-family: 'Times New Roman';">I.R.S. Identification Nos. of above persons (entities only)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">Bihua Chen</div>
              <div>&#160;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">2</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Check the Appropriate Box if a Member of a Group (See Instructions)</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top;">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top;">
              <div><font style="font-family: 'Times New Roman';">(a)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[ ]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">&#160;</td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">(b)</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 36pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">[x]</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">3</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">SEC Use Only</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">4</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Citizenship or Place of Organization.</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">United States</div>
            </td>
          </tr>
          <tr>
            <td colspan="2" rowspan="4" style="width: 17.76%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: center; font-family: 'Times New Roman';">Number</div>
              <div style="text-align: center; font-family: 'Times New Roman';">of Shares</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Beneficially</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Owned by</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Each</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Reporting</div>
              <div style="text-align: center; font-family: 'Times New Roman';">Person With</div>
            </td>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">5</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">6</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Voting Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares</div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">7</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Sole Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">0 shares</div>
            </td>
          </tr>
          <tr>
            <td style="width: 82.24%; vertical-align: middle; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div><font style="font-family: 'Times New Roman';">8</font><font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt" class="BRFWTab">&#160;</font><font style="font-family: 'Times New Roman';">Shared Dispositive Power</font></div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="margin-left: 12pt; font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">9</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Aggregate Amount Beneficially Owned by Each Reporting Person</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">2,082,000 shares</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">10</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="text-align: justify; font-family: 'Times New Roman';">Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)</div>
              <div style="text-align: justify; font-family: 'Times New Roman';">&#160;&#160;&#160;&#160;[ ] <font style="color: #000000;">N/A</font></div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">11</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Percent of Class Represented by Amount in Row (9)*</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">5.15%</div>
              <div style="font-family: 'Times New Roman';"> <br>
              </div>
              <div style="font-family: 'Times New Roman';">Refer to Item 4 below.</div>
            </td>
          </tr>
          <tr>
            <td style="width: 6.79%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">12</div>
            </td>
            <td colspan="2" style="width: 93.01%; vertical-align: top; border-top: 1px solid rgb(0, 0, 0); border-bottom: 1px solid rgb(0, 0, 0);">
              <div style="font-family: 'Times New Roman';">Type of Reporting Person (See Instructions)</div>
              <div>&#160;</div>
              <div style="font-family: 'Times New Roman';">IN (Individual)</div>
            </td>
          </tr>

      </table>
    </div>
    <div>
      <div> <br>
      </div>
      <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
        <div style="page-break-after: always;" class="BRPFPageBreak">
          <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
      </div>
      <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 15%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
            </td>
            <td style="width: 85%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">68062P106</div>
            </td>
          </tr>

      </table>
    </div>
    <div><br>
    </div>
    <div style="text-indent: -54pt; margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;1.</div>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z70e6f9967c6a4556a2184d38c1685ae1" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 6.68%; vertical-align: top;">&#160;</td>
          <td style="width: 6.94%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(a)</div>
          </td>
          <td style="width: 86.39%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Name of Issuer</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.68%; vertical-align: top;">&#160;</td>
          <td style="width: 6.94%; vertical-align: top;">&#160;</td>
          <td style="width: 86.39%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Olema Pharmaceuticals, Inc.</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.68%; vertical-align: top;">&#160;</td>
          <td style="width: 6.94%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(b)</div>
          </td>
          <td style="width: 86.39%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Address of Issuer&#8217;s Principal Executive Offices</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.68%; vertical-align: top;">&#160;</td>
          <td style="width: 6.94%; vertical-align: top;">&#160;</td>
          <td style="width: 86.39%; vertical-align: top;">
            <div>&#160;</div>
            <div style="color: #000000; font-family: 'Times New Roman';">512 2nd Street, 4th Floor, San Francisco, CA 94107</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div style="text-indent: -54pt; margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;2.</div>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z8c11af22541f460b9cccb0d306877cf7" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(a)</div>
          </td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Name of Person Filing</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">&#160;</td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund III, LP</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP III, LLC</div>
            <div><font style="font-family: 'Times New Roman';">Cormorant Asset Management, LP<br>
                Bihua Chen<br>
              </font>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(b)</div>
          </td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Address of Principal Business Office or, if none, Residence</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">&#160;</td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">200 Clarendon Street, 52nd Floor</div>
            <div style="font-family: 'Times New Roman';">Boston, MA 02116</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(c)</div>
          </td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Citizenship</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">&#160;</td>
          <td style="width: 86.36%; vertical-align: top;">
            <div>&#160;</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund II, LP - Delaware</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC - Delaware</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare Fund III, LP - Delaware</div>
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP III, LLC - Delaware</div>
            <div style="font-family: 'Times New Roman';">Cormorant Asset Management, LP - Delaware<br>
              Bihua Chen - United States</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(d)</div>
          </td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Title of Class of Securities</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">&#160;</td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Common Stock</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(e)</div>
          </td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CUSIP Number</div>
          </td>
        </tr>
        <tr>
          <td style="width: 6.69%; vertical-align: top;">&#160;</td>
          <td style="width: 6.95%; vertical-align: top;">&#160;</td>
          <td style="width: 86.36%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">68062P106</div>
          </td>
        </tr>

    </table>
    <div>
      <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 15%; vertical-align: top;"><br>
            </td>
            <td style="width: 85%; vertical-align: top;"><br>
            </td>
          </tr>

      </table>
      <div> <br>
      </div>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z0c262e1367024538bd853a6dbb5d462d" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;3.</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">If this statement is filed pursuant to &#167;&#167;240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="zef86801640a64b6c885ae4569f2b428e" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(a)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(b)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(c)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">Insurance Company as defined in Section 3(a)(19) of the Act</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(d)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(e)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">An investment adviser in accordance with &#167;240.13d-1(b)(1)(ii)(E);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(f)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">An employee benefit plan or endowment fund in accordance with &#167;240.13d-1(b)(1)(ii)(F);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(g)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">A parent holding company or control person in accordance with &#167; 240.13d-1(b)(1)(ii)(G);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(h)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(i)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(j)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">A non-U.S. institution in accordance with &#167;240.13d&#8211;1(b)(1)(ii)(J);</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(k)</div>
          </td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">[ ]</div>
          </td>
          <td style="vertical-align: top;">
            <div style="text-align: justify; font-family: 'Times New Roman';">Group, in accordance with &#167;240.13d-1(b)(1)(ii)(K).</div>
          </td>
        </tr>

    </table>
    <br>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;4.</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership***</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-indent: 36pt; font-family: 'Times New Roman';">Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.</div>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(a)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Amount Beneficially Owned***</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td colspan="2" rowspan="1" style="width: 36pt; vertical-align: top;">
            <div>&#160;</div>
            <div style="font-family: 'Times New Roman';">The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(a) for each such Reporting Person.</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(b)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Percent of Class</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td colspan="2" rowspan="1" style="width: 36pt; vertical-align: top;">
            <div>&#160;</div>
            <div style="font-family: 'Times New Roman';">The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(b) for each such Reporting Person.</div>
          </td>
        </tr>

    </table>
    <br>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(c)</div>
          </td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Number of shares as to which such person has:</div>
            <div>&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(i)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">sole power to vote or to direct the vote</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>

    </table>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(ii)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">shared power to vote or to direct the vote</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(iii)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">sole power to dispose or to direct the disposition of</div>
            <div style="font-family: 'Times New Roman';"> <br>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">&#160;</td>
          <td style="width: 36pt; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">(iv)</div>
          </td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">shared power to dispose or to direct the disposition of</div>
          </td>
        </tr>
        <tr>
          <td rowspan="1" style="width: 36pt; vertical-align: top;">&#160;</td>
          <td colspan="3" rowspan="1" style="width: 36pt; vertical-align: top;">&#160;
            <div style="font-family: 'Times New Roman';">The information set forth in Rows 5 through 11 on the cover page for each Reporting Person is hereby incorporated by reference into this Item 4(c) for each such Reporting Person.</div>
            &#160;&#160;</td>
        </tr>

    </table>
    <div>&#160;</div>
    <br>
    <div>&#160;</div>
    <div style="margin-left: 36pt; font-family: 'Times New Roman';">*** Shares reported herein for Cormorant Asset Management, LP represent shares which are beneficially owned by Cormorant Private Healthcare Fund II, LP (&#8220;Fund II&#8221;) and Cormorant Private
      Healthcare Fund III, LP (&#8220;Fund III&#8221;), as reported herein.&#160; Cormorant Private Healthcare GP II, LLC and Cormorant Private Healthcare GP III, LLC serve as the general partners of Fund II and Fund III, respectively.&#160; Cormorant Asset Management, LP
      serves as the investment manager to Fund II and Fund III.&#160; Bihua Chen serves as the managing member of Cormorant Private Healthcare GP II, LLC, Cormorant Private Healthcare GP III, LLC and the general partner of Cormorant Asset Management, LP.&#160; Each
      of the Reporting Persons disclaims beneficial ownership of the shares reported herein except to the extent of its or his pecuniary interest therein.</div>
    <div>&#160;</div>
    <div style="margin-left: 36pt; font-family: 'Times New Roman';">The percentages reported herein with respect to the Reporting Persons&#8217; holdings are calculated based upon a statement in the Issuer's Quarterly Report on Form 10-Q for the quarterly period
      ended September 30, 2022, as filed with the Securities and Exchange Commission on November 8, 2022, that there were 40,455,427 shares of Common Stock outstanding as of November 4, 2022.</div>
    <div style="text-align: justify; margin-left: 36pt; font-family: 'Times New Roman';"> <br>
    </div>
    <div>&#160;</div>
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; font-weight: bold;"><font style="font-family: 'Times New Roman';">Item&#160;5</font>.<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt"> <br>
              </font></td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of Five Percent or Less of a Class</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="text-align: justify; text-indent: -54pt; margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;"><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt; font-family: 'Times New Roman';">If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of
      the class of securities, check the following [&#160; ].</div>
    <div>&#160;</div>
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; font-weight: bold;"><font style="font-family: 'Times New Roman';">Item&#160;6</font>.<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt"> <br>
              </font></td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Ownership of More than Five Percent on Behalf of Another Person</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="text-align: justify; text-indent: -54pt; margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;"><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z9e4b83b55beb434baa9e34a51d7621dc" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman';">Not applicable.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 54pt; vertical-align: top; font-weight: bold;"><font style="font-family: 'Times New Roman';">Item&#160;7</font>.<font style="display: inline-block; text-indent: 0px; font-size: 1px; width: 12pt"> <br>
              </font></td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="text-align: justify; text-indent: -54pt; margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;"><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zda8cc31306c54672a366d491048f9a7d" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman';">Not applicable.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z327e61c15488474d9c34e9c709a84edb" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;8.</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Identification and Classification of Members of the Group</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z42d3401751aa4ff1b86a9e960446c724" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman';">Not applicable.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zf6406a6d194f430d88b281efe2337a70" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;9.</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Notice of Dissolution of Group</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z348e6de543094fe48d63e05339ef413f" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; align: right;"><br>
          </td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman';">Not applicable.</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="ze1dd1daf1e414b29b7f11a8f4297b31c" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Item&#160;10.</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Certification</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; font-family: 'Times New Roman';">By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with
      the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. </div>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z67a1953eb59c49bb991a9b00637b873a" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; font-family: 'Times New Roman'; font-weight: bold;">Exhibits</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div style="font-family: 'Times New Roman'; font-weight: bold;">Exhibit</div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div> <br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="ze1f13349be7c4df787fdbe4f3e62acc2" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 54pt; vertical-align: top; align: right; font-family: 'Times New Roman'; font-weight: bold;">99.1</td>
          <td style="width: auto; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Joint Filing Agreement by and among the Reporting Persons, incorporated by reference to Exhibit 99.1 to the Schedule 13G filed by the Reporting Persons with
              <div style="color: rgb(0, 0, 0);">the Securities and Exchange Commission on November 23, 2020.</div>
            </div>
          </td>
        </tr>

    </table>
    <div>&#160;</div>
    <div> <br>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;" noshade="noshade"></div>
    </div>
    <div>
      <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 15%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">CUSIP NO.</div>
            </td>
            <td style="width: 85%; vertical-align: top;">
              <div style="font-family: 'Times New Roman';">68062P106</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="margin-left: 54pt; font-family: 'Times New Roman'; font-weight: bold;"> <br>
    </div>
    <div style="font-weight: bold;">SIGNATURE</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; font-family: 'Times New Roman';">After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this Statement is true, complete and correct.</div>
    <div>&#160;</div>
    <div style="font-family: 'Times New Roman';">February 14, 2023</div>
    <div>&#160;</div>
    <div><br>
    </div>
    <div><br>
    </div>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE FUND II, LP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By:</div>
          </td>
          <td style="width: 49%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP II, LLC</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">its General Partner</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE GP II, LLC</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE FUND III, LP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By:</div>
          </td>
          <td style="width: 49%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Cormorant Private Healthcare GP III, LLC</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">its General Partner</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CORMORANT PRIVATE HEALTHCARE GP III, LLC</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">&#160;</td>
          <td style="width: 49%; vertical-align: top;">&#160;</td>
        </tr>

    </table>
    <div> </div>
    <table style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: rgb(0, 0, 0);" border="0" cellpadding="0" cellspacing="0">

        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td colspan="2" style="vertical-align: top;">
            <div style="font-family: 'Times New Roman';">CORMORANT ASSET MANAGEMENT, LP</div>
          </td>
        </tr>
        <tr>
          <td style="width: 50%; vertical-align: top;">&#160;</td>
          <td style="width: 1%; vertical-align: top;">
            <div style="font-family: 'Times New Roman';">By:</div>
          </td>
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            <div style="font-family: 'Times New Roman';">Cormorant Asset Management GP, LLC</div>
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            <div style="font-family: 'Times New Roman';">its General Partner</div>
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            <div style="font-family: 'Times New Roman';">By: <u>/s/ Bihua Chen</u></div>
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            <div style="font-family: 'Times New Roman';">Bihua Chen, Managing Member</div>
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          <td style="width: 50%; vertical-align: top;">&#160;</td>
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          <td style="width: 49%; vertical-align: top;">&#160;</td>
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          <td style="width: 50%; vertical-align: top;">&#160;</td>
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            <div style="font-family: 'Times New Roman';"><u>/s/ Bihua Chen</u></div>
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            <div style="font-family: 'Times New Roman';">Bihua Chen</div>
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