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Commitments and Contingencies - Additional Information (Details)		1 Months Ended	3 Months Ended		9 Months Ended
	Nov. 29, 2024 USD ($)	Jun. 30, 2022 USD ($)	Sep. 30, 2025 USD ($) Item	Sep. 30, 2024 USD ($)	Sep. 30, 2025 USD ($) Item	Sep. 30, 2024 USD ($)
Loss Contingencies [Line Items]
Research and development			$ 39,951,000	$ 33,226,000	$ 114,477,000	$ 92,218,000
Novartis Pharma Agreement
Loss Contingencies [Line Items]
Exclusive negotiation period after receipt of written notice	30 days
Exclusive negotiation period maximum	120 days
Proposed sale negotiation period	45 days
Aggregate amount of units actually supplied	$ 275,000,000
Novartis Pharma Agreement | Bio Medical Research Inc
Loss Contingencies [Line Items]
Number of patients | Item			60		60
Aurigene Agreement
Loss Contingencies [Line Items]
Milestone payments to be paid to collaborative partner		$ 60,000,000
Upfront payment, research and development.		8,000,000
Research and development					$ 10,000,000
Aurigene Agreement | Commercial Milestone
Loss Contingencies [Line Items]
Milestone payments to be paid to collaborative partner		$ 370,000,000
Aurigene Agreement | Clinical Cevelopment and Regulatory Milestones
Loss Contingencies [Line Items]
Research and development						$ 5,000,000

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