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Equity Incentive Plans - Summary of Weighted Average Assumptions used to Estimate Fair Value (Details) - Options to purchase common stock - $ / shares
6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk-free interest rate 0.70% 1.20%
Expected volatility 93.10% 91.80%
Expected dividend yield 0.00% 0.00%
Expected term (in years) 6 years 2 months 4 days 6 years 3 months
Weighted average grant date fair value per share (in dollars per share) $ 22.39 $ 11.97