    <SEC-DOCUMENT>0001370053-22-000024-index.html : 20220429
    <SEC-HEADER>0001370053-22-000024.hdr.sgml : 20220429
    <ACCEPTANCE-DATETIME>20220429160644
    ACCESSION NUMBER:		0001370053-22-000024
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		55
    CONFORMED PERIOD OF REPORT:	20220425
    ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20220429
    DATE AS OF CHANGE:		20220429

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ANAPTYSBIO, INC
    		CENTRAL INDEX KEY:			0001370053
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				203828755
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37985
    		FILM NUMBER:		22875232

    	BUSINESS ADDRESS:
    		STREET 1:		10770 WATERIDGE CIRCLE, SUITE 210
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		858-362-6295

    	MAIL ADDRESS:
    		STREET 1:		10770 WATERIDGE CIRCLE, SUITE 210
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ANAPTYSBIO INC
    		DATE OF NAME CHANGE:	20080828

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ANAPTYS BIOSCIENCES INC
    		DATE OF NAME CHANGE:	20060724
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>anab-20220425.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: anab-20220425.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.1
    <SEQUENCE>2
    <FILENAME>lizzulamendedandrestated.htm
    <DESCRIPTION>EX-10.1
    <TEXT>
    Document 2 - file: lizzulamendedandrestated.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.2
    <SEQUENCE>3
    <FILENAME>loumeauamendedandrestate.htm
    <DESCRIPTION>EX-10.2
    <TEXT>
    Document 3 - file: loumeauamendedandrestate.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3
    <SEQUENCE>4
    <FILENAME>mulroyamendedandrestated.htm
    <DESCRIPTION>EX-10.3
    <TEXT>
    Document 4 - file: mulroyamendedandrestated.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>5
    <FILENAME>anab-20220425.xsd
    <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT
    <TEXT>
    Document 5 - file: anab-20220425.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.DEF
    <SEQUENCE>6
    <FILENAME>anab-20220425_def.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION DEFINITION LINKBASE DOCUMENT
    <TEXT>
    Document 6 - file: anab-20220425_def.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>7
    <FILENAME>anab-20220425_lab.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT
    <TEXT>
    Document 7 - file: anab-20220425_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>8
    <FILENAME>anab-20220425_pre.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT
    <TEXT>
    Document 8 - file: anab-20220425_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>lizzulamendedandrestated001.jpg
    <TEXT>
    Document 9 - file: lizzulamendedandrestated001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>lizzulamendedandrestated002.jpg
    <TEXT>
    Document 10 - file: lizzulamendedandrestated002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>lizzulamendedandrestated003.jpg
    <TEXT>
    Document 11 - file: lizzulamendedandrestated003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>lizzulamendedandrestated004.jpg
    <TEXT>
    Document 12 - file: lizzulamendedandrestated004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>lizzulamendedandrestated005.jpg
    <TEXT>
    Document 13 - file: lizzulamendedandrestated005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>lizzulamendedandrestated006.jpg
    <TEXT>
    Document 14 - file: lizzulamendedandrestated006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>lizzulamendedandrestated007.jpg
    <TEXT>
    Document 15 - file: lizzulamendedandrestated007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>lizzulamendedandrestated008.jpg
    <TEXT>
    Document 16 - file: lizzulamendedandrestated008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>lizzulamendedandrestated009.jpg
    <TEXT>
    Document 17 - file: lizzulamendedandrestated009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>lizzulamendedandrestated010.jpg
    <TEXT>
    Document 18 - file: lizzulamendedandrestated010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>lizzulamendedandrestated011.jpg
    <TEXT>
    Document 19 - file: lizzulamendedandrestated011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>lizzulamendedandrestated012.jpg
    <TEXT>
    Document 20 - file: lizzulamendedandrestated012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>lizzulamendedandrestated013.jpg
    <TEXT>
    Document 21 - file: lizzulamendedandrestated013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>loumeauamendedandrestate001.jpg
    <TEXT>
    Document 22 - file: loumeauamendedandrestate001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>loumeauamendedandrestate002.jpg
    <TEXT>
    Document 23 - file: loumeauamendedandrestate002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>loumeauamendedandrestate003.jpg
    <TEXT>
    Document 24 - file: loumeauamendedandrestate003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>loumeauamendedandrestate004.jpg
    <TEXT>
    Document 25 - file: loumeauamendedandrestate004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>loumeauamendedandrestate005.jpg
    <TEXT>
    Document 26 - file: loumeauamendedandrestate005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>loumeauamendedandrestate006.jpg
    <TEXT>
    Document 27 - file: loumeauamendedandrestate006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>loumeauamendedandrestate007.jpg
    <TEXT>
    Document 28 - file: loumeauamendedandrestate007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>loumeauamendedandrestate008.jpg
    <TEXT>
    Document 29 - file: loumeauamendedandrestate008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>loumeauamendedandrestate009.jpg
    <TEXT>
    Document 30 - file: loumeauamendedandrestate009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>loumeauamendedandrestate010.jpg
    <TEXT>
    Document 31 - file: loumeauamendedandrestate010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>loumeauamendedandrestate011.jpg
    <TEXT>
    Document 32 - file: loumeauamendedandrestate011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>loumeauamendedandrestate012.jpg
    <TEXT>
    Document 33 - file: loumeauamendedandrestate012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>loumeauamendedandrestate013.jpg
    <TEXT>
    Document 34 - file: loumeauamendedandrestate013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>mulroyamendedandrestated001.jpg
    <TEXT>
    Document 35 - file: mulroyamendedandrestated001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>mulroyamendedandrestated002.jpg
    <TEXT>
    Document 36 - file: mulroyamendedandrestated002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>mulroyamendedandrestated003.jpg
    <TEXT>
    Document 37 - file: mulroyamendedandrestated003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>38
    <FILENAME>mulroyamendedandrestated004.jpg
    <TEXT>
    Document 38 - file: mulroyamendedandrestated004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>39
    <FILENAME>mulroyamendedandrestated005.jpg
    <TEXT>
    Document 39 - file: mulroyamendedandrestated005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>40
    <FILENAME>mulroyamendedandrestated006.jpg
    <TEXT>
    Document 40 - file: mulroyamendedandrestated006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>41
    <FILENAME>mulroyamendedandrestated007.jpg
    <TEXT>
    Document 41 - file: mulroyamendedandrestated007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>42
    <FILENAME>mulroyamendedandrestated008.jpg
    <TEXT>
    Document 42 - file: mulroyamendedandrestated008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>43
    <FILENAME>mulroyamendedandrestated009.jpg
    <TEXT>
    Document 43 - file: mulroyamendedandrestated009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>44
    <FILENAME>mulroyamendedandrestated010.jpg
    <TEXT>
    Document 44 - file: mulroyamendedandrestated010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>45
    <FILENAME>mulroyamendedandrestated011.jpg
    <TEXT>
    Document 45 - file: mulroyamendedandrestated011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>46
    <FILENAME>mulroyamendedandrestated012.jpg
    <TEXT>
    Document 46 - file: mulroyamendedandrestated012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>47
    <FILENAME>mulroyamendedandrestated013.jpg
    <TEXT>
    Document 47 - file: mulroyamendedandrestated013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>48
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 48 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>49
    <FILENAME>anab-20220425_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 49 - file: anab-20220425_htm.html

    Document 49 - RAW XML: anab-20220425_htm.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EXCEL
    <SEQUENCE>50
    <FILENAME>Financial_Report.xlsx
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 50 - file: Financial_Report.xlsx

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>51
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 51 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>52
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 52 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>53
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 53 - file: FilingSummary.html

    Document 53 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>55
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 55 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>56
    <FILENAME>0001370053-22-000024-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 56 - file: 0001370053-22-000024-xbrl.zip

    </DOCUMENT>
    </SEC-DOCUMENT>