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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Income Statement [Abstract]        
Revenue from Contract with Customer, Product and Service [Extensible Enumeration] Collaboration Revenue [Member] Collaboration Revenue [Member] Collaboration Revenue [Member] Collaboration Revenue [Member]
Collaboration revenue $ 22,263 $ 10,971 $ 50,034 $ 18,150
Operating expenses:        
Research and development 37,824 41,997 79,004 79,039
General and administrative 10,609 9,295 24,739 21,633
Total operating expenses 48,433 51,292 103,743 100,672
Loss from operations (26,170) (40,321) (53,709) (82,522)
Other income (expense), net:        
Interest income 3,654 4,623 8,067 9,207
Non-cash interest expense for the sale of future royalties (19,606) (10,953) (37,667) (17,270)
Other income (expense), net 3,531 0 5,433 (2)
Total other expense, net (12,421) (6,330) (24,167) (8,065)
Loss before income taxes (38,591) (46,651) (77,876) (90,587)
Provision for income taxes (39) (9) (83) (9)
Net loss (38,630) (46,660) (77,959) (90,596)
Unrealized (loss) gain on available for sale securities (167) 209 (311) 382
Comprehensive loss $ (38,797) $ (46,451) $ (78,270) $ (90,214)
Net loss per common share:        
Basic (in dollars per share) $ (1.34) $ (1.71) $ (2.62) $ (3.35)
Diluted (in dollars per share) $ (1.34) $ (1.71) $ (2.62) $ (3.35)
Weighted-average number of shares outstanding:        
Basic (in shares) 28,810 27,356 29,722 27,079
Diluted (in shares) 28,810 27,356 29,722 27,079