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Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Income Statement [Abstract]        
Revenue from Contract with Customer, Product and Service [Extensible Enumeration] Collaboration Revenue [Member] Collaboration Revenue [Member] Collaboration Revenue [Member] Collaboration Revenue [Member]
Collaboration revenue $ 76,320 $ 30,017 $ 126,354 $ 48,167
Operating expenses:        
Research and development 31,407 42,212 110,411 121,251
General and administrative 10,209 10,562 34,948 32,195
Total operating expenses 41,616 52,774 145,359 153,446
Income (loss) from operations 34,704 (22,757) (19,005) (105,279)
Other income (expense), net:        
Interest income 2,924 5,324 10,991 14,531
Non-cash interest expense for the sale of future royalties (22,515) (15,413) (60,182) (32,683)
Other (expense) income, net 0 (5) 5,433 (7)
Total other expense, net (19,591) (10,094) (43,758) (18,159)
Income (loss) before income taxes 15,113 (32,851) (62,763) (123,438)
Provision for income taxes 0 0 (83) (9)
Net income (loss) 15,113 (32,851) (62,846) (123,447)
Unrealized gain (loss) on available for sale securities 53 1,174 (258) 1,556
Comprehensive income (loss) $ 15,166 $ (31,677) $ (63,104) $ (121,891)
Net income (loss) per common share:        
Basic (in dollars per share) $ 0.54 $ (1.14) $ (2.16) $ (4.46)
Diluted (in dollars per share) $ 0.52 $ (1.14) $ (2.16) $ (4.46)
Weighted-average number of shares outstanding:        
Basic (in shares) 27,833 28,893 29,085 27,688
Diluted (in shares) 29,018 28,893 29,085 27,688