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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Revenues
Research and development	$ 12,268,960	$ 14,987,628	$ 8,175,878
Operating expenses
Selling, general and administrative	12,303,050	13,713,635	10,582,068
Research and development	16,679,712	19,710,673	13,130,529
Patent expenses	909,946	909,376	1,009,053
Litigation expense	0	0	14,407,494
Lease termination	1,225,421	0	0
Interest on PharmAthene liability	0	11,668,900	0
Total operating expenses	31,118,129	46,002,584	39,129,144
Operating loss	(18,849,169)	(31,014,956)	(30,953,266)
Interest expense	14,758,140	2,395,517	266,726
Loss from increase in fair value of warrant liability	4,738,753	894,785	0
Backstop fee	0	(1,764,240)	0
Other income, net	16,788	102,324	42,202
Reorganization items, net	0	(3,716,902)	(7,811,551)
Loss before income taxes	(38,329,274)	(39,684,076)	(38,989,341)
Benefit/(Provision) for income taxes	2,093,790	(13,884)	(461,983)
Net and comprehensive loss	$ (36,235,484)	$ (39,697,960)	$ (39,451,324)
Earnings (loss) per share: basic and diluted (usd per share)	$ (0.46)	$ (0.69)	$ (0.73)
Weighted average shares outstanding: basic and diluted (in shares)	78,874,494	57,188,503	53,777,687

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