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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Unaudited) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Revenues
Research and development	$ 2,661,216	$ 4,264,561	$ 4,409,150	$ 9,466,347
Operating expenses
Selling, general and administrative	2,880,394	3,058,244	5,936,940	5,928,113
Research and development	3,312,181	5,067,838	6,320,007	11,428,327
Patent expenses	178,332	197,017	396,805	437,615
Total operating expenses	6,370,907	8,323,099	12,653,752	17,794,055
Operating loss	(3,709,691)	(4,058,538)	(8,244,602)	(8,327,708)
Decrease In Fair Value Of Warrants	360,285	294,356	(2,942,829)	(331,853)
Interest expense	(3,843,161)	(3,652,496)	(7,591,979)	(7,261,412)
Gain (loss) from change in fair value of warrant liability	(400,000)	(300,000)	(2,942,829)	(331,853)
Other income, net	144,152	8,066	146,387	12,484
Loss before income taxes	(7,048,415)	(7,408,612)	(18,633,023)	(15,908,489)
Current Income Tax Expense (Benefit)	(2,849)		(497)
Provision for income taxes		(92,825)		(207,895)
Net and comprehensive loss	$ (7,051,264)	$ (7,501,437)	$ (18,633,520)	$ (16,116,384)
Loss per share: basic and diluted	$ (0.09)	$ (0.10)	$ (0.24)	$ (0.20)
Weighted average shares outstanding: basic and diluted	79,094,230	78,840,312	79,066,768	78,808,903

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