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Note 3 - Procurement Contracts and Research Agreements (Details Textual)
$ in Thousands
 3 Months Ended 9 Months Ended 12 Months Ended
Oct. 31, 2022
USD ($)
Sep. 28, 2022
USD ($)
May 12, 2022
USD ($)
Jan. 13, 2021
USD ($)
Apr. 03, 2020
USD ($)
Sep. 10, 2018
USD ($)
Sep. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jul. 31, 2019
USD ($)
Contract with Customer, Liability, Revenue Recognized                   $ 3,500        
The 19C BARDA Contract [Member]                            
Number of Courses to Be Delivered           1,488,000                
Government Contract, Value of Award             $ 602,500     602,500        
Government Contract, Base Period, Value of Award for Delivery and Support Activities           $ 51,700 51,700     $ 51,700        
Base Period of Performance (Year)                   5 years        
Government Contract Value Related To Exercised Options                   $ 268,900        
Government Contract, Value, Payments Currently Specified as Unexercised Options                   $ 281,900        
Base Period of Performance, Exercise of Options, Term (Year)                   10 years        
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Delivery of Courses           $ 11,100                
Government Contract, Base Period, Number of Deliveries           35,700                
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Manufacture of Courses           $ 8,000                
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Advanced Development           32,000                
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Supportive Procurement Activities           $ 600                
Proceeds from Delivery of Courses                   $ 11,100        
Number of Courses Delivered                   35,700        
Proceeds from Other Base Period Activities                   $ 17,100        
Government Contract, Value of Unexercised Options, Supportive Procurement Activities             5,600     5,600        
The 19C BARDA Contract [Member] | Transferred over Time [Member]                            
Contract with Customer, Liability, Revenue Recognized             2,700   $ 1,100 4,600 $ 2,800      
The 19C BARDA Contract [Member] | Transferred at Point in Time [Member]                            
Contract with Customer, Liability, Revenue Recognized                   7,200        
The 19C BARDA Contract [Member] | IV TPOXX [Member]                            
Government Contract, Base Period, Number of Courses Manufactured           20,000                
Government Contract Option Value Of Award For Delivery and Support Activities Manufacture of Courses                         $ 10,200  
Government Contract, Value, Payments Related to Exercised Options, Funding of Post-Marketing Activities             $ 3,600     $ 3,600        
Number of Manufacturing Steps             2     2        
The 19C BARDA Contract [Member] | IV BDS [Member]                            
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Manufacture of Courses           $ 3,200                
Proceeds from the Manufacture of Courses                   $ 3,200        
Proceeds from the Delivery of Courses                   4,300        
Contract with Customer, Liability, Total             $ 10,200     10,200   $ 3,200    
Government Contract, Value, Payments Currently Specified as Unexercised Options, Manufacture of Courses             20,500     20,500        
Government Contract, Value of Courses Manufactured Upon Exercise of Options             $ 20,500     $ 20,500        
Government Contract, Number of Options for Manufacture of Product             3     3        
Government Contract, Courses Manufactured Upon Exercise of Options             64,000     64,000        
The 19C BARDA Contract [Member] | IV FDP Containing IV BDS [Member]                            
Contract with Customer, Liability, Total             $ 300     $ 300        
Contract with Customer, Liability, Revenue Recognized                   2,900        
The 19C BARDA Contract [Member] | Oral TPOXX [Member]                            
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Manufacture of Courses                   25,600        
Number of Courses Delivered                         726,140  
Government Contract, Value, Payments Related to Exercised Options, Procurement of Raw Materials             225,100     225,100     $ 11,200  
Government Contract, Value, Payments Related to Exercised Options, Delivery of Courses                         213,900  
Government Contract, Value, Payments Related to Exercised Options, Funding of Post-Marketing Activities                         $ 14,600  
Proceeds from Payments Received for Post-marketing Activities                   8,100        
Government Contract, Value, Payments Related to Unexercised Options, Delivery of Courses             225,100     225,100        
The 19C BARDA Contract [Member] | IV FDP [Member]                            
Government Contract, Value, Payments Currently Specified as Unexercised Options, Manufacture of Courses             $ 51,200     $ 51,200        
Government Contract, Number of Options for Manufacture of Product             3     3        
Government Contract, Courses Manufactured Upon Exercise of Options             64,000     64,000        
The 19C BARDA Contract [Member] | Maximum [Member]                            
Number of Courses to Be Delivered           212,000                
IC BARDA [Member] | Transferred at Point in Time [Member]                            
Contract with Customer, Liability, Revenue Recognized             $ 0   0   0      
U.S. Department of Defense (“DoD”) [Member] | Oral TPOXX [Member]                            
Government Contract, Value, Payments Currently Specified as Unexercised Options   $ 5,500 $ 3,800                      
Contract with Customer, Liability, Revenue Recognized               $ 3,600            
Government Contract, Value Ordered   $ 5,200 $ 3,600                      
Government Contract, Value, Option Exercised             3,800              
International Procurement [Member]                            
Contract with Customer, Liability, Revenue Recognized             61,300     $ 66,200        
International Procurement [Member] | Oral TPOXX [Member]                            
Contract with Customer, Liability, Revenue Recognized                   66,000        
International Procurement [Member] | Oral TPOXX [Member] | Subsequent Event [Member]                            
Government Contract, Value of Award $ 77,000                          
Government Contract, Value, Payments Currently Specified as Unexercised Options 6,000                          
International Procurement [Member] | Oral TPOXX [Member] | Subsequent Event [Member] | CANADA                            
Government Contract, Value of Award 39,000                          
International Procurement [Member] | Oral TPOXX [Member] | Subsequent Event [Member] | Europe, Asia Pacific and the Middle East [Member]                            
Government Contract, Value of Award $ 38,000                          
Meridian Contract [Member]                            
Contract with Customer, Liability, Revenue Recognized                 2,300   12,700      
Meridian Contract [Member] | Oral TPOXX [Member]                            
Government Contract, Value of Award       $ 33,000                    
Contract with Customer, Liability, Revenue Recognized             35,000         10,000    
Government Contract, Term (Year)       5 years                    
Government Contract, Increased Value of Award       $ 45,000                    
Government Contract, Award, Target Delivery Amount             0     0        
Canadian Contract [Member] | Meridian Medical Technologies [Member]                            
Contract with Customer, Liability, Revenue Recognized                       $ 4,000    
Government Contract, Term (Year)         4 years                  
Government Contract, Award, Target Delivery Amount             4,000     4,000        
Other Commitment, Total         $ 14,000                  
Government Contract, Unexercised Options                   6,000        
The PEP Label Expansion R & D Contract with the Department of Defense [Member]                            
Government Contract, Value of Award                           $ 19,500
Contract with Customer, Liability, Revenue Recognized             4,200   $ 1,300 13,100 $ 2,000      
Government Contract, Increased Value of Award                           27,000
Government Contract, Initial Award                           $ 12,400
Contract With Customer Liability Remaining Revenue To Be Recognized             $ 11,200     $ 11,200