    <SEC-DOCUMENT>0001193125-23-099219-index.html : 20230412
    <SEC-HEADER>0001193125-23-099219.hdr.sgml : 20230412
    <ACCEPTANCE-DATETIME>20230412161314
    ACCESSION NUMBER:		0001193125-23-099219
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20221231
    FILED AS OF DATE:		20230412
    DATE AS OF CHANGE:		20230412
    EFFECTIVENESS DATE:		20230412

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			CASTLE BIOSCIENCES INC
    		CENTRAL INDEX KEY:			0001447362
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
    		IRS NUMBER:				770701774
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38984
    		FILM NUMBER:		23815846

    	BUSINESS ADDRESS:
    		STREET 1:		505 S FRIENDSWOOD DRIVE
    		STREET 2:		SUITE 401
    		CITY:			FRIENDSWOOD
    		STATE:			TX
    		ZIP:			77546
    		BUSINESS PHONE:		866-788-9007

    	MAIL ADDRESS:
    		STREET 1:		505 S FRIENDSWOOD DRIVE
    		STREET 2:		SUITE 401
    		CITY:			FRIENDSWOOD
    		STATE:			TX
    		ZIP:			77546
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>d441757dars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: d441757dars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>