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STOCK-BASED COMPENSATION (Tables)
12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Share-Based Payment Arrangement, Restricted Stock Unit, Activity
A summary of RSU award activity during the year ended December 31, 2025 is as follows:
NUMBER OF UNITSWEIGHTED AVERAGE GRANT-DATE FAIR VALUE
Outstanding RSU awards as of January 1, 2025— $— 
Granted1,167,325 11.71 
Vested(30,300)12.04 
Forfeited(420,175)10.56 
Outstanding RSU awards as of December 31, 2025716,850 $12.37 
Schedule of Stock Option Valuation Assumptions
The weighted-average assumptions that the Company used in the Black-Scholes option-pricing model to determine the grant-date fair value of stock options granted for the years ended December 31, 2025 and 2024 were as follows:
YEAR ENDED DECEMBER 31,
20252024
Risk-free interest rate
3.96 %4.30 %
Expected term (in years)5.325.91
Expected volatility83.59 %81.92 %
Expected dividend yield0.00 %0.00 %
Schedule of Option Activity
A summary of option activity during the year ended December 31, 2025 is as follows (in thousands except share and per share data):
NUMBER OF
OPTIONS
WEIGHTED-
AVERAGE
EXERCISE PRICE
WEIGHTED-AVERAGE
REMAINING
CONTRACTUAL
TERM (IN YEARS)
AGGREGATE
INTRINSIC VALUE
Outstanding as of January 1, 20255,384,760 $42.19 7.18$7,395 
Granted84,000 14.82 
Exercised(73,655)2.05 $695 
Cancelled or forfeited(783,495)54.42 
Expired(709,904)49.82 
Outstanding as of December 31, 20253,901,706 $38.52 5.59$12,209 
Options exercisable as of December 31, 20253,091,868 $34.77 5.16$12,035 
Schedule of Stock-based Compensation Expense
Total stock-based compensation expense recorded as research and development and general and administrative expenses, respectively, for employees, directors and non-employees during the years ended December 31, 2025 and 2024 is as follows (in thousands):

YEAR ENDED DECEMBER 31,
20252024
Research and development$13,288 $18,294 
General and administrative15,408 16,578 
Total stock-based compensation expense$28,696 $34,872