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Equity Incentive Plans (Tables) | 9 Months Ended
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Sep. 30, 2019
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] |
Summary of Stock Option Activity | The following table summarizes stock option activity during the nine months ended September 30, 2019:
|  | Shares Subject to Options Outstanding |  |  | Weighted- Average |  |  |  |  |
|  |  |  |  |  | Weighted- |  |  | Remaining |  |  |  |  |
|  |  |  |  |  | Average Exercise |  |  | Contractual Life |  |  | Aggregate |
|  | Shares |  |  | Price |  |  | (Years) |  |  | Intrinsic Value |
|  |  |  |  |  |  |  |  |  |  |  |  |  | (in thousands) |
Outstanding as of December 31, 2018 |  |  | 5,107,329 |  |  | $ | 7.51 |  |  |  | 9.7 |  |  | $ | 16,343 |
Options granted |  |  | 3,441,901 |  |  | $ | 20.79 |  |  |  |  |  |  |  |  |
Option exercised |  |  | (173,712 | ) |  | $ | 3.04 |  |  |  |  |  |  |  |  |
Options forfeited/cancelled |  |  | (275,657 | ) |  | $ | 12.30 |  |  |  |  |  |  |  |  |
Outstanding as of September 30, 2019 |  |  | 8,099,861 |  |  | $ | 13.09 |  |  |  | 9.2 |  |  | $ | 44,015 |
Options vested and exercisable as of September 30, 2019 |  |  | 644,722 |  |  | $ | 3.88 |  |  |  | 8.7 |  |  | $ | 8,323 |
Summary of Restricted Stock Activity | The summary of the Company’s restricted stock activity is as follows:
|  | Number of |  |  | Weighted- |
|  | Restricted |  |  | Average |
|  | Stock Units |  |  | Grant Date |
|  | Outstanding |  |  | Fair Value |
Nonvested at December 31, 2018 |  |  | 7,482,032 |  |  | $ | 4.01 |
Granted |  |  | — |  |  |  | — |
Vested |  |  | (2,428,863 | ) |  | $ | 4.11 |
Forfeited |  |  | — |  |  |  | — |
Nonvested at September 30, 2019 |  |  | 5,053,169 |  |  | $ | 3.96 |
Stock-Based Compensation Expense Reported in Condensed Consolidated Statements of Operations | Stock-based compensation expense has been reported in the Company’s condensed consolidated statements of operations as follows (in thousands):
|  | Three months ended |  |  | Nine months ended |
|  | September 30, |  |  | September 30, |
|  | 2019 |  |  | 2018 |  |  | 2019 |  |  | 2018 |
Research and development |  | $ | 2,727 |  |  | $ | 144 |  |  | $ | 6,483 |  |  | $ | 200 |
General and administrative |  |  | 3,001 |  |  |  | 18,025 |  |  |  | 7,474 |  |  |  | 19,948 |
Total stock-based compensation |  | $ | 5,728 |  |  | $ | 18,169 |  |  | $ | 13,957 |  |  | $ | 20,148 |

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