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v3.19.3

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2019 | Sep. 30, 2018
Cash flows from operating activities |  |
Net loss | $ (125,609) | $ (108,175)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 625 | 163
Stock-based compensation expense | 13,957 | 20,148
In process research and development expenses | 2,000 | 49,659
Amortization of long-term debt discount and issuance costs | 148 |
Amortization of premium on investments, net of accretion of discounts | (2,296) |
Net realized gain on investments | (1) |
Changes in operating assets and liabilities: |  |
Operating lease right of use assets and liabilities, net | 49 |
Prepaid expenses and other current assets | (2,807) | (1,442)
Other assets | 2,886 | (823)
Accounts payable | 333 | 3,525
Accrued expenses | (760) | 3,263
Accrued research and development expenses | 8,518 | 7,778
Accrued compensation and benefits | 2,263 |
Accrued interest expense |  | (117)
Net cash used in operating activities | (100,694) | (26,021)
Cash flows from investing activities |  |
Research and development asset acquisitions, net of cash acquired | (2,000) | (17,721)
Purchase of investments | (399,393) | (115,141)
Maturities of investments | 205,750 |
Sales of investments | 4,004 |
Purchase of property and equipment | (2,438) | (3,168)
Net cash used in investing activities | (194,077) | (136,030)
Cash flows from financing activities |  |
Proceeds from issuance of common stock in a public offering, net | 291,311 |
Proceeds from the issuance of long-term debt, net of issuance costs of $1,778 | 28,222 |
Proceeds from the exercise of stock options | 527 |
Repayment of notes payable to related parties |  | (40)
Net cash provided by financing activities | 320,060 | 303,003
Net increase in cash, cash equivalents and restricted cash | 25,289 | 140,952
Cash, cash equivalents and restricted cash, at the beginning of the period | 105,419 | 315
Cash, cash equivalents and restricted cash, at the end of the period | 130,708 | 141,267
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 854 |
Supplemental disclosure of noncash investing and financing activities: |  |
Acquisition of in-process research and development through issuance of stock |  | 19,284
Issuance of Series A convertible preferred stock to convert debt and accrued interest |  | 6,124
Recognition of operating lease right of use asset | 12,458 |
Recognition of operating lease liabilities | 13,182 |
Conversion of convertible preferred stock to common stock | 338,367 |
Change in unrealized gain on marketable securities, net of tax | 510 | 235
Change in unrealized loss on foreign currency translations, net of tax | 121 |
Unpaid property and equipment | $ 127 |
Series A Convertible Preferred Stock |  |
Cash flows from financing activities |  |
Proceeds from issuance of convertible preferred stock, net |  | 73,491
Series B Convertible Preferred Stock |  |
Cash flows from financing activities |  |
Proceeds from issuance of convertible preferred stock, net |  | $ 229,552

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