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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share (Details) - shares | 3 Months Ended | 6 Months Ended
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Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 90,054,533 | 32,505,645 | 102,376,433 | 32,505,645
2027 Notes |  |  |  |
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 0 | 12,321,900 | 12,321,900 | 12,321,900
Shares issuable upon exercise of stock options |  |  |  |
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 35,190,675 | 19,739,058 | 35,190,675 | 19,739,058
Shares issuable upon exercise of Equity Option granted to Chiesi |  |  |  |
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 22,396,498 | 0 | 22,396,498 | 0
Shares issuable upon exercise of warrants |  |  |  |
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 32,467,360 | 0 | 32,467,360 | 0
Non-vested shares under restricted stock grants |  |  |  |
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] |  |  |  |
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) | 0 | 444,687 | 0 | 444,687

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 260 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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