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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share (Details) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 90,054,533 32,505,645 102,376,433 32,505,645
2027 Notes        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 0 12,321,900 12,321,900 12,321,900
Shares issuable upon exercise of stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 35,190,675 19,739,058 35,190,675 19,739,058
Shares issuable upon exercise of Equity Option granted to Chiesi        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 22,396,498 0 22,396,498 0
Shares issuable upon exercise of warrants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 32,467,360 0 32,467,360 0
Non-vested shares under restricted stock grants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 0 444,687 0 444,687