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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share (Details) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 102,318,469 63,579,374 102,318,469 63,579,374
2027 Notes        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 12,321,900 12,321,900 12,321,900 12,321,900
Shares issuable upon exercise of stock options        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 35,095,400 18,358,583 35,095,400 18,358,583
Shares issuable upon exercise of Equity Option granted to Chiesi        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 22,433,809 0 22,433,809 0
Shares issuable upon exercise of warrants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 32,467,360 32,467,360 32,467,360 32,467,360
Non-vested shares under restricted stock grants        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) 0 431,531 0 431,531