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Significant Agreements and Contracts - Additional Information (Details)
$ in Thousands
3 Months Ended 9 Months Ended
May 03, 2024
USD ($)
performanceObligation
license
Sep. 30, 2024
USD ($)
Jun. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Effect of exchange rate changes on revenue              
Total revenue   $ 9,480   $ 0 $ 105,322 $ 0  
Deferred revenue, current   20,327     20,327   $ 0
Long-term contract liabilities   43,780     43,780   0
Accounts receivable   6,588     6,588   0
Chiesi              
Effect of exchange rate changes on revenue              
Number of significant distinct performance obligations | performanceObligation 4            
Number of licenses granted | license 2            
Commercial efforts contribution, percentage 50.00%            
Commercialization activities performance, percentage 50.00%            
Up-front, nonrefundable payment received $ 160,000            
Loyalty term, expiration period 10 years            
Development cost reimbursement payment $ 160,000            
Contract with customer, liability, fair value of equity option $ 500            
Total revenue   9,480     105,322    
Contract Liability   $ 64,107     $ 64,107   $ 0
Revenue recognition period   4 years 3 months 18 days     4 years 3 months 18 days    
Accounts receivable   $ 6,600     $ 6,600    
Chiesi | US License              
Effect of exchange rate changes on revenue              
Number of significant distinct performance obligations | performanceObligation 2            
Total revenue     $ 88,800        
Chiesi | Revenue from PAH research and development service performance obligation satisfied during reporting period              
Effect of exchange rate changes on revenue              
Total revenue   $ 9,500     $ 16,600    
Chiesi | Maximum              
Effect of exchange rate changes on revenue              
Collaboration agreement, regulatory milestones receivable $ 146,000            
Collaboration agreement, sales milestones receivable $ 180,000