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Stockholders' Equity (Details) |  |  |  |  |  |  |  | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Jul. 24, 2023 USD ($) $ / shares shares | Jul. 15, 2022 USD ($) $ / shares shares | May 21, 2020 USD ($) $ / shares shares | Sep. 06, 2018 $ / shares shares | May 21, 2018 $ / shares shares | Jan. 04, 2018 USD ($) | Dec. 03, 2015 USD ($) $ / shares shares | Dec. 31, 2024 USD ($) vote shares | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | May 03, 2024 USD ($) day
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, voting right per share | vote |  |  |  |  |  |  |  | 1 |  |  |
Issuance of common stock (in shares) | shares |  |  | 9,433,963 |  |  |  |  |  |  |  |
Offering price (in dollars per share) | $ / shares |  |  | $ 13.25 |  |  |  |  |  |  |  |
Cash flows from financing activities |  |  | $ 117,100,000 |  |  |  |  |  |  |  |
Payments of stock issuance costs |  | $ 200,000 |  |  |  |  |  |  |  |  |
Warrant term | 5 years |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of private placement | $ 212,100,000 |  |  |  |  |  |  | $ 0 | $ 201,323,000 | $ 119,946,000 |
Issuance of common stock |  |  |  |  |  |  |  |  | $ 201,323,000 | $ 119,946,000 |
Shares of common stock, repurchase (in shares) | shares |  |  |  |  |  |  |  | 0 |  |  |
Founder |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock (in shares) | shares |  |  |  | 1,795,023 | 251,547 |  |  |  |  |  |
Issuance price per share (in dollars per share) | $ / shares |  |  |  | $ 9.63 | $ 2.61 |  |  |  |  |  |
Percentage of fully diluted share capital |  |  |  |  |  | 15.00% |  |  |  |  |
Increased in equity capital amount |  |  |  |  |  | $ 300,000,000.0 |  |  |  |  |
Additional shares of restricted stock subject to vesting restrictions (in shares) | shares |  |  |  | 1,795,023 | 251,547 |  |  |  |  |  |
Founder Shares |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock (in shares) | shares |  |  |  |  |  |  | 9,160,888 |  |  |  |
Issuance price per share (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.0001 |  |  |  |
Issuance of common stock |  |  |  |  |  |  | $ 4,100 |  |  |  |
Common stock vesting percentage |  |  |  |  |  | 50.00% |  |  |  |  |
Common stock vesting period |  |  |  |  |  | 5 years |  |  |  |  |
Chiesi Farmaceutici S.p.A And Chiesi USA, Inc. |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Tender offer or exchange offer, percentage of shares outstanding |  |  |  |  |  |  |  |  |  |  | 50.00%
Purchase price of each share subject to equity option, percentage of daily volume-weighted average per share price |  |  |  |  |  |  |  |  |  |  | 107.50%
Purchase price of each share subject to equity option, number of trading days | day |  |  |  |  |  |  |  |  |  |  | 30
Purchase price of each share subject to equity option, minimum price threshold (in dollars per share) |  |  |  |  |  |  |  |  |  |  | 163.00%
Contract with customer, liability, fair value of equity option |  |  |  |  |  |  |  |  |  |  | $ 500,000
Maximum | Chiesi Farmaceutici S.p.A And Chiesi USA, Inc. |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Equity option owned by chiesi |  |  |  |  |  |  |  |  |  |  | 9.90%
Private Placement |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price (in dollars per share) | $ / shares | $ 1.63125 | $ 7.21 |  |  |  |  |  |  |  |  |
Shares issued in transition (in shares) | shares | 129,869,440 | 16,649,365 |  |  |  |  |  |  |  |  |
Net proceeds, after deducting underwriting discounts, commissions, and offering expenses |  | $ 120,100,000 |  |  |  |  |  |  |  |  |
Payments of stock issuance costs | $ 10,800,000 |  |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ / shares | $ 2.04 |  |  |  |  |  |  |  |  |  |
Warrant term | 5 years |  |  |  |  |  |  |  |  |  |
Private Placement | Officer, Director, Employee Or Consultant |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering price (in dollars per share) | $ / shares | $ 1.85125 |  |  |  |  |  |  |  |  |  |
Private Placement | Maximum |  |  |  |  |  |  |  |  |  |  |
Stockholders Equity Deficit [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of warrants (in shares) | shares | 32,467,360 |  |  |  |  |  |  |  |  |  |

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