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Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2024
Accounting Policies [Abstract] |
Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share | The table below provides potentially dilutive securities not included in the calculation of the diluted net loss per share because to do so would be anti-dilutive (in common stock equivalent shares):
| December 31,
| 2024 |  | 2023 |  | 2022
2027 Notes | 12,321,900 |  |  | 12,321,900 |  |  | 12,321,900 |
Shares issuable upon exercise of stock options | 34,416,337 |  |  | 23,626,115 |  |  | 17,487,165 |
Shares issuable upon exercise of Chiesi Equity Option | 22,433,809 |  |  | — |  |  | — |
Shares issuable upon exercise of warrants | 32,467,360 |  |  | 32,467,360 |  |  | — |
Non-vested shares under restricted stock grants | — |  |  | 427,698 |  |  | 1,350,035 |
Total potentially dilutive securities | 101,639,406 |  |  | 68,843,073 |  |  | 31,159,100 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
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