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Research Collaboration and License Agreements - Additional Information (Details)
1 Months Ended 6 Months Ended 12 Months Ended
Nov. 30, 2017
USD ($)
Target
Jun. 30, 2022
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2021
USD ($)
Jul. 31, 2021
USD ($)
Jun. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jun. 30, 2019
USD ($)
Research Collaboration And License Agreements [Line Items]                  
Collaboration contract asset and other assets   $ 11,700,000     $ 12,500,000   $ 0 $ 0  
Pfizer, Inc.                  
Research Collaboration And License Agreements [Line Items]                  
Upfront non-refundable payment and certain additional payments received   3,500,000 $ 28,000,000            
Pfizer, Inc. | Collaboration Agreement                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised           $ 650,000,000      
Collaboration agreement direct and incremental costs incurred   12,900,000              
Collaboration contract asset and other assets   12,900,000              
Pfizer, Inc. | Regulatory and Sales-Based Milestones | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised           1,400,000,000      
Pfizer, Inc. | Regulatory Milestone Related to Marketing Approvals                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised           400,000,000      
Pfizer, Inc. | Sales-Based Milestones                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised           $ 1,000,000,000      
Pfizer, Inc. | Development Milestone Payments | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   225,000,000              
Pfizer, Inc. | Sales Based Milestone Payments                  
Research Collaboration And License Agreements [Line Items]                  
Upfront non-refundable payment and certain additional payments received   0              
Pfizer, Inc. | Sales Based Milestone Payments | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   550,000,000              
Pfizer, Inc. | Option Payments To License Agreement | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   37,500,000              
Bayer Collaboration Agreement                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised                 $ 17,500,000
Bayer Collaboration Agreement | Research Funding Payments                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   10,500,000              
Bayer Collaboration Agreement | Research Funding Payments | Scenario Forecast                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised       $ 12,000,000          
Bayer Collaboration Agreement | Development Milestone Payments                  
Research Collaboration And License Agreements [Line Items]                  
Upfront non-refundable payment and certain additional payments received   0              
Bayer Collaboration Agreement | Development Milestone Payments | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised                 197,500,000
Bayer Collaboration Agreement | Sales Based Milestone Payments                  
Research Collaboration And License Agreements [Line Items]                  
Upfront non-refundable payment and certain additional payments received   0              
Bayer Collaboration Agreement | Sales Based Milestone Payments | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised                 $ 490,000,000
Genentech, Inc. and F. Hoffman-La Roche Ltd.                  
Research Collaboration And License Agreements [Line Items]                  
Upfront non-refundable payment and certain additional payments received $ 34,500,000                
Additional upfront non-refundable amount received under previous agreement $ 11,000,000                
Number of designated targets | Target 10                
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Regulatory Milestone Related to Marketing Approvals                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   52,500,000              
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Development Milestone Payments | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   44,000,000              
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Option Payments To License Agreement | Maximum                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   27,500,000              
Genentech, Inc. and F. Hoffman-La Roche Ltd. | Commercial Milestones                  
Research Collaboration And License Agreements [Line Items]                  
Contract revenue receivable if milestones achieved or options for all targets exercised   60,000,000              
Upfront non-refundable payment and certain additional payments received   $ 0