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Commitments and Contingencies (Details) - USD ($) $ in Millions |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 04, 2022 | Jul. 31, 2013 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Commitments And Contingencies [Line Items] |  |  |  |  |
Loss contingency |  |  | $ 7.0 |  |
Yale University |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Royalty payment |  |  | $ 0.1 | $ 0.1 | $ 0.2
Yale University | License, First Licensed Product | Success-Based Milestone Payments |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Required milestone payments |  | $ 3.0 |  |  |
Yale University | License, Second Licensed Product | Success-Based Milestone Payments |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Required milestone payments |  | 1.5 |  |  |
Minimum | Yale University |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Annual payment for license |  | 0.1 |  |  |
Royalty payment |  | 0.2 |  |  |
Maximum | Yale University |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Royalty payment |  | $ 0.5 |  |  |
Maximum | Foundation Medicine, Inc. | Success-Based Milestone Payments |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Milestone payments (up to low) | $ 10.0 |  |  |  |

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