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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Millions
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Consolidated Statements of Operations      
Revenue $ 131,400,000 $ 53,600,000 $ 25,900,000
Operating expenses:      
Research and development 315,000,000.0 180,400,000 108,400,000
General and administrative 79,600,000 61,600,000 38,300,000
Total operating expenses 394,600,000 242,000,000.0 146,700,000
Loss from operations (263,200,000) (188,400,000) (120,800,000)
Other income (expense)      
Other income, net 200,000 2,500,000 2,100,000
Interest income, net 12,000,000.0 1,800,000 3,500,000
Total other income 12,200,000 4,300,000 5,600,000
Net loss before income taxes and loss from equity method investment (251,000,000.0) (184,100,000) (115,200,000)
Income tax expense (20,900,000) 0 0
Loss from equity method investment (10,600,000) (6,900,000) (4,100,000)
Net loss $ (282,500,000) $ (191,000,000.0) $ (119,300,000)
Net loss per common share - basic (in usd per share) $ (5.31) $ (3.82) $ (3.02)
Net loss per common share - diluted (in usd per share) $ (5.31) $ (3.82) $ (3.02)
Weighted average common shares outstanding - basic (in shares) 53.2 50.0 39.5
Weighted average common shares outstanding - diluted (in shares) 53.2 50.0 39.5
Consolidated Statements of Comprehensive Loss      
Net loss $ (282,500,000) $ (191,000,000.0) $ (119,300,000)
Other comprehensive loss:      
Unrealized (loss) gain on available-for-sale securities (14,500,000) (5,200,000) 500,000
Comprehensive loss $ (297,000,000.0) $ (196,200,000) $ (118,800,000)