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Consolidated Statements of Changes in Stockholders' Equity - USD ($)
shares in Millions, $ in Millions
Total
At-the-Market Offering
Common Shares
Common Shares
At-the-Market Offering
Accumulated Deficit
Additional Paid-in Capital
Additional Paid-in Capital
At-the-Market Offering
Accumulated Other Comprehensive Loss
Beginning balance (in shares) at Dec. 31, 2019     38.5          
Beginning balance at Dec. 31, 2019 $ 226.6   $ 0.0   $ (372.6) $ 599.1   $ 0.1
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuances of common stock, net (in shares)     6.6 2.5        
Issuances of common stock, net 431.9 $ 64.1       431.9 $ 64.1  
Stock-based compensation 30.2         30.2    
Net loss (119.3)       (119.3)      
Restricted stock vesting (in shares)     0.4          
Proceeds from exercise of stock options (in shares)     0.5          
Proceeds from exercise of stock options 8.2         8.2    
Unrealized gain (loss) on available-for-sale securities 0.5             0.5
Ending balance (in shares) at Dec. 31, 2020     48.5          
Ending balance at Dec. 31, 2020 642.2   $ 0.0   (491.9) 1,133.5   0.6
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Issuances of common stock, net (in shares)     3.5          
Issuances of common stock, net 259.9         259.9    
Stock-based compensation 57.1         57.1    
Net loss (191.0)       (191.0)      
Restricted stock vesting (in shares)     0.2          
Proceeds from exercise of stock options (in shares)     0.8          
Proceeds from exercise of stock options 18.7         18.7    
Unrealized gain (loss) on available-for-sale securities $ (5.2)             (5.2)
Ending balance (in shares) at Dec. 31, 2021 53.0   53.0          
Ending balance at Dec. 31, 2021 $ 781.7   $ 0.0   (682.9) 1,469.2   (4.6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                
Stock-based compensation 75.5         75.5    
Net loss (282.5)       (282.5)      
Proceeds from exercise of stock options (in shares)     0.2          
Proceeds from exercise of stock options 4.8   $ 0.1     4.7    
Unrealized gain (loss) on available-for-sale securities $ (14.6)             (14.6)
Ending balance (in shares) at Dec. 31, 2022 53.2   53.2          
Ending balance at Dec. 31, 2022 $ 564.9   $ 0.1   $ (965.4) $ 1,549.4   $ (19.2)